WordNet

draw from specific cases for more general cases (同)generalise, extrapolate, infer
become systemic and spread throughout the body; "this kind of infection generalizes throughout the immune system" (同)generalise
speak or write in generalities (同)generalise
not biologically differentiated or adapted to a specific function or environment; "the hedgehog is a primitive and generalized mammal" (同)generalised
a disorder of the central nervous system characterized by loss of consciousness and convulsions

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2014/12/04 02:20:21」(JST)

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Generalized epilepsy, also known as primary generalized epilepsy or idiopathic epilepsy, is a form of epilepsy characterised by generalised seizures with no apparent cause.^[1] Generalized seizures, as opposed to partial seizures, are a type of seizure that impairs consciousness and distorts the electrical activity of the whole or a larger portion of the brain (which can be seen, for example, on electroencephalography, EEG).^[2]

Generalized epilepsy is primary because the epilepsy is the originally diagnosed condition itself, as opposed to secondary epilepsy, which occurs as a symptom of a known as diagnosed condition.^[3]

Manifestation

Generalized seizures can be either absence seizures, myoclonic seizures, clonic seizures, tonic-clonic seizures or atonic seizures.

Generalized seizures occur in various seizure syndromes, including myoclonic epilepsy, familial neonatal convulsions, childhood absence epilepsy, absence epilepsy, infantile spasms (West's syndrome), Juvenile Myoclonic Epilepsy and Lennox-Gastaut syndrome.

Prognosis

Most generalized epilepsy starts during childhood. While some patients outgrow their epilepsy during adolescence and no longer need medication, in others, the condition remains for life, thereby requiring lifelong medication and monitoring.

Treatment

Six anti-epileptic drugs are approved for use in cases of suspected primary generalized epilepsy:

Felbamate
Levetiracetam
Zonisamide
Topiramate
Valproate
Lamotrigine

All anti-epileptic drugs (including the above) can be used in cases of partial seizures.

References

^ http://www.med.nyu.edu/cec/epilepsy/types/primary_generalized.html
^ http://www.nervous-system-diseases.com/primary-generalized-epilepsy.html
^ http://www.pediatricservices.com/prof/prof-05.htm

UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

1. 成人におけるてんかんのマネージメントの概要 overview of the management of epilepsy in adults
2. 小児における痙攣およびてんかん：分類、病因、および臨床的特徴 seizures and epilepsy in children classification etiology and clinical features
3. 痙攣発作およびてんかんの病態生理 pathophysiology of seizures and epilepsy
4. 成人における初回痙攣発作の評価 evaluation of the first seizure in adults
5. 成人におけるてんかんの初期治療 initial treatment of epilepsy in adults

English Journal

Sleep disturbances among patients with epilepsy in Nigeria.

Komolafe MA, Sunmonu TA1, Ogunrin OA, Disu JO, Ezeala BA, Abubakar SA, Iwuoso E.
Annals of African medicine.Ann Afr Med.2015 Apr-Jun;14(2):103-8. doi: 10.4103/1596-3519.149880.
BACKGROUND: There is a complex inter-relationship between sleep disorders and epilepsy, and there are few studies in Nigeria on sleep disorders in epilepsy. This study was carried out to determine the prevalence, pattern and predictors of sleep disturbances among persons with epilepsy (PWE).MATERIAL
PMID 25693818

A 3 year audit of adult epilepsy care in a Nigerian tertiary hospital (2011-2013).

Sanya EO1, Wahab KW, Desalu OO, Bello HA, Ademiluyi BA, Alaofin WA, Busari K.
Annals of African medicine.Ann Afr Med.2015 Apr-Jun;14(2):97-102. doi: 10.4103/1596-3519.149878.
BACKGROUND: Epilepsy audit provides positive feedback to physicians that could assist in improving the quality of health care services provided for patients. This study was carried out to evaluate care given to people with epilepsy with the aim of determining potentials for improvement.MATERIALS AND
PMID 25693817

Japanese Journal

抗てんかん薬と妊娠に関する国際共同研究（EURAP）日本国内登録症例の検討（第2報）

てんかん研究 33(3), 663-671, 2016
NAID 130005126514

病気について知りたい! 臨床講座(83)てんかん

Pharma tribune : なりたい薬剤師になる! 7(11), 5-13, 2015-11
NAID 40020656240

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リンク元	「全般てんかん」「generalized nonconvulsive epilepsy」「generalized seizure disorder」「全般性てんかん」
関連記事	「generalize」「generalized」「epilepsy」