WordNet

(genetics) a segment of DNA that is involved in producing a polypeptide chain; it can include regions preceding and following the coding DNA as well as introns between the exons; it is considered a unit of heredity; "genes were formerly called factors" (同)cistron, factor
informal term for information; "give me the gen on your new line of computers"

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1. 甲状腺結節および非髄様甲状腺癌におけるオンコジーンおよび腫瘍抑制遺伝子 oncogenes and tumor suppressor genes in thyroid nodules and nonmedullary thyroid cancer
2. 機械的人工換気の肺障害の炎症メカニズム inflammatory mechanisms of lung injury during mechanical ventilation
3. 成長ホルモンの生理学 physiology of growth hormone
4. エストロゲン作用の分子生物学および生理学 molecular biology and physiology of estrogen action
5. 骨格の正常な発達および骨形成ならびに骨吸収の調節 normal skeletal development and regulation of bone formation and resorption

Potent anti-aging activity of Aruncus dioicus, a native plant of Ulleung-do, South Korea, in CCD-986sk fibroblasts via suppression of matrix metalloproteinases.

Kim DH, Moon YS, An BJ, Son JH.SourceTeam of Product Development, Daegu Gyeongbuk Institute for Oriental Medicine Industry, Gyeongsan-si, Gyeongbuk, 712-260, South Korea.
Journal of natural medicines.J Nat Med.2012 Oct;66(4):631-6. Epub 2012 Feb 17.
Aruncus dioicus var. kamtschaticus HARA, also known as goat's beard, is a native plant in Ulleung-do, South Korea. It has been used as a remedy in skin care, detoxification, blood stanching, tonsillitis. High performance liquid chromatography with diode array detection was used for partial validati
PMID 22350144

Functional genetic variants of c-Jun and their interaction with smoking and drinking increase the susceptibility to lung cancer in southern and eastern Chinese.

Huang B, Liu B, Yang L, Li Y, Cheng M, Huang D, Wang H, Zhang X, Zheng J, Li Q, Ji W, Zhou Y, Lu J.SourceThe Institute for Chemical Carcinogenesis, The State Key Lab of Respiratory Disease, Guangzhou Medical University, Guangzhou, People's Republic of China.
International journal of cancer. Journal international du cancer.Int J Cancer.2012 Sep 1;131(5):E744-58. doi: 10.1002/ijc.27407. Epub 2012 Feb 18.
Human proto-oncogene c-Jun and c-Fos assemble the activator protein-1 complex which is a crucial transcription factor responding to environmental factors and promotes tumorgenesis. We hypothesized that genetic variants in these two genes may alter the carriers' susceptibility to lung cancer. In two
PMID 22189957

Visualization of Neural Activity in Insect Brains Using a Conserved Immediate Early Gene, Hr38

Fujita Nozomi,Nagata Yuka,Nishiuchi Takumi,Sato Makoto,Iwami Masafumi,Kiya Taketoshi
Current Biology 23(20), 2063-2070, 2013-10-21
… Immediate early genes (IEGs), such as c-fos, whose expression is transiently and rapidly upregulated upon neural activity, are powerful tools for detecting behavior-related neural activity in vertebrates [4, 5]. … These findings indicate that Hr38 is a novel and conserved insect neural activity marker gene that will be useful for a wide variety of neuroethologic studies. …
NAID 120005349182

Heterogeneous Nuclear Ribonucleoprotein R Cooperates with Mediator to Facilitate Transcription Reinitiation on the c-Fos Gene

Fukuda Aya,Shimada Miho,Nakadai Tomoyoshi,Nishimura Ken,Hisatake Koji,福田綾,西村健,久武幸司
PLoS ONE 8(8), e72496, 2013-08
… The c-fos gene responds to extracellular stimuli and undergoes robust but transient transcriptional activation. … Here we show that heterogeneous nuclear ribonucleoprotein R (hnRNP R) facilitates transcription reinitiation of the c-fos promoter in vitro in cooperation with Mediator. … Knockdown of hnRNP R in mouse cells compromised rapid induction of the c-fos gene but did not affect transcription of constitutive genes. …
NAID 120005324989

Electroconvulsive seizures activate anorexigenic signals in the ventromedial nuclei of the hypothalamus.

Segi-Nishida Eri,Sukeno Mamiko,Imoto Yuki,Kira Toshihiko,Sakaida Mari,Tsuchiya Soken,Sugimoto Yukihiko,Okuno Yasushi
Neuropharmacology 71, 164-173, 2013-08
… To address this issue, we investigated the changes in gene expression in microdissected-VMH samples in response to ECS in mice, and examined the behavioral effects of ECS on feeding behavior. … ECS significantly induced the expression of immediate-early genes such as Fos, Fosb, and Jun, as well as Bdnf, Adcyap1, Hrh1, and Crhr2 in the VMH. … Given that signals of these gene products are suggested to have anorexigenic roles in the VMH, we also examined the effect of ECS on food intake and body weight. …
NAID 120005295921