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English Journal

Selective liquid-chromatographic determination of native fluorescent biogenic amines in human urine based on fluorous derivatization.

Sakaguchi Y, Yoshida H, Hayama T, Itoyama M, Todoroki K, Yamaguchi M, Nohta H.SourceFaculty of Pharmaceutical Sciences, Fukuoka University, 8-19-1 Nanakuma, Johnan, Fukuoka 814-0180, Japan.
Journal of chromatography. A.J Chromatogr A.2011 Aug 19;1218(33):5581-6. Epub 2011 May 27.
A liquid chromatographic (LC) derivatization method for simple and selective determination of catecholamines and indoleamines in human urine has been developed. This method uses "fluorous interaction" in which perfluoroalkyl compounds show affinity with each other. The amino groups of native fluores
PMID 21752389

A delivery system to avoid self-aggregation and to improve in vitro and in vivo skin delivery of a phthalocyanine derivative used in the photodynamic therapy.

Rossetti FC, Lopes LB, Carollo AR, Thomazini JA, Tedesco AC, Bentley MV.SourceFaculdade de Ciencias Farmaceuticas de Ribeirao Preto, Universidade de Sao Paulo, Av. do Cafe, s/n, 14040-903, Ribeirao Preto, SP, Brazil.
Journal of controlled release : official journal of the Controlled Release Society.J Control Release.2011 Jul 7. [Epub ahead of print]
The hydrophilic character and aggregation phenomena exhibited by the photosensitizer zinc phthalocyanine tetrasulfonate (ZnPcSO(4)) make it difficult for this compound to penetrate the skin, and reduce the compound's photodynamic efficacy. A microemulsion (ME) was developed to increase the skin pene
PMID 21763732

Labeling of alprenolol with fluorescent aryl iodide as a reagent based on Mizoroki-Heck coupling reaction.

Kishikawa Naoya,Ohkuma Mizuho,Wada Mitsuhiro,Ohyama Kaname,Ikeda Rie,Nakashima Kenichiro,Kuroda Naotaka
Journal of Chromatography. A 1218(20), 3002-3006, 2011-05-20
… The fluorescent labeling of alprenolol with DIBI was achieved in the presence of palladium acetate as a catalyst, and the labeled alprenolol was detected fluorometrically. …
NAID 120003238480

Mechanisms Underlying the Anti-inflammatory Effects of the Ca2+/Calmodulin Antagonist CV-159 in Cultured Vascular Smooth Muscle Cells

Usui Tatsuya,Yamawaki Hideyuki,Kamibayashi Masato,Okada Muneyoshi,Hara Yukio
Journal of Pharmacological Sciences advpub(0), 1006140405, 2010
… Furthermore, CV-159 inhibited TNF-induced reactive oxygen species (ROS) production as determined fluorometrically using dichlorodihydrofluorescein diacetate. …
NAID 130000251930