関: dichloralantipyrine

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2014/06/10 08:21:05」(JST)

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Dichloralphenazone is a 1:2 mixture of antipyrine with chloral hydrate. In combination with paracetamol and isometheptene, it is the active ingredient of medications for migraine and vascular (tension) headaches, including Epidrin and Midrin. Performance impairments are common with this drug and caution is advised, for example when driving motor vehicles. Additional uses of dichloralphenazone include sedation for the treatment of short-term insomnia, although there are probably better drug choices for the treatment of insomnia.^[1]

References

^ Hindmarch I; Parrott AC. (1980). "The effects of combined sedative and anxiolytic preparations on subjective aspects of sleep and objective measures of arousal and performance the morning following nocturnal medication. I: Acute doses.". Arzneimittelforschung. 30 (6): 1025–8. PMID 6106498.

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1. 小児における片頭痛のマネージメント management of migraine headache in children

English Journal

Chiropractic management of essential tremor and migraine: a case report.

Hubbard TA, Kane JD.SourceAssociate Professor, Palmer College of Chiropractic, Davenport, IA.
Journal of chiropractic medicine.J Chiropr Med.2012 Jun;11(2):121-6. doi: 10.1016/j.jcm.2011.10.006.
OBJECTIVE: The purpose of this case report is to describe the chiropractic management of a 39-year-old woman with essential tremors and migraine headaches.CLINICAL FEATURES: A 39-year-old woman presented with essential tremors and migraine headaches, which occurred 2 to 3 times per week. The essenti
PMID 23204956

Health care utilization in patients with migraine: demographics and patterns of care in the ambulatory setting.

Gibbs TS, Fleischer AB Jr, Feldman SR, Sam MC, O'Donovan CA.SourceDepartment of Dermatology, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA.
Headache.Headache.2003 Apr;43(4):330-5.
BACKGROUND: Migraine affects people of all races and both sexes. Migraineurs suffer both financial losses and impaired quality of life. Recent progress in the treatment of migraine has not been made readily available to all who suffer the condition.OBJECTIVE: To assess outpatient health care deliver
PMID 12656703

Schedule of controlled substances: placement of dichloralphenazone into Schedule IV. Final rule.

Drug Enforcement Administration (DEA), Department of Justice.AbstractWith the issuance of this final rule, the Acting Administrator of the DEA specifically lists the substance dichloralphenazone, including its salts, isomers, and salts of isomers in Schedule IV of the Controlled Substances Act (CSA, 21 U.S.C. 801 et seq.). As a result of this rule, the regulatory controls and criminal sanctions of Schedule IV will be applicable to the manufacture, distribution, dispensing, importation and exportation of dichloralphenazone and products containing dichloralphenazone.
Federal register.Fed Regist.2001 Aug 16;66(159):42943-4.
With the issuance of this final rule, the Acting Administrator of the DEA specifically lists the substance dichloralphenazone, including its salts, isomers, and salts of isomers in Schedule IV of the Controlled Substances Act (CSA, 21 U.S.C. 801 et seq.). As a result of this rule, the regulatory con
PMID 11794309

「ジクロラルフェナゾン」

Dichloralphenazone
Combination of
Phenazone	Analgesic
Chloral hydrate	Sedative
Clinical data
MedlinePlus	a601064
Legal status	Schedule IV (US)
Routes	Oral
Identifiers
CAS number	480-30-8
ATC code	N05CC04
PubChem	CID 10188
DrugBank	DB01495
ChemSpider	9776
UNII	YYX637R279
KEGG	D03785
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