comparative genomic hybridization technique

比較ゲノムハイブリダイゼーション法

WordNet

1. relating to or based on or involving comparison; "comparative linguistics"
2. the comparative form of an adjective or adverb; "`faster is the comparative of the adjective `fast"; "`less famous is the comparative degree of the adjective `famous"; "`more surely is the comparative of the adverb `surely" (同)comparative degree
3. (genetics) the act of mixing different species or varieties of animals or plants and thus to produce hybrids (同)hybridisation, crossbreeding, crossing, cross, interbreeding, hybridizing
4. a practical method or art applied to some particular task
5. the branch of genetics that studies organisms in terms of their genomes (their full DNA sequences)

PrepTutorEJDIC

1. 『比較の』,比較による / 比較的,かなりの / 比較級の / 比較級
2. 〈U〉(科学・芸術などの)『技巧』,技術 / 〈C〉(技術・技巧を示す)『手法』,表現方法;腕前

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• 1. 着床前スクリーニング preimplantation genetic screening
• 2. ゲノム疾患：概要 genomic disorders an overview
• 3. 産科における染色体マイクロアレイの利用 use of chromosomal microarray in obstetrics
• 4. 小頭症に対する臨床遺伝学的アプローチ microcephaly a clinical genetics approach
• 5. 頭頸部の扁平上皮癌化：分子学的および遺伝学的変化 head and neck squamous cell carcinogenesis molecular and genetic alterations

English Journal

• Comparative genomic hybridization in detection of DNA changes in canine lymphomas.

• Drážovská M1, Šiviková K1, Dianovský J1, Horňák M2.
• Animal science journal = Nihon chikusan Gakkaiho.Anim Sci J.2016 Apr 25. doi: 10.1111/asj.12582. [Epub ahead of print]
• In this study, chromosomal imbalances in tumor tissues (lymphomas) and nucleotide changes in tumor suppressor TP53 were studied in a Bernese Mountain dog bitch and a cross breed bitch. Using comparative genomic hybridization, numerous chromosomal rearrangements were detected, which indicated the het
• PMID 27112539

• Genotype/phenotype correlation in a female patient with 21q22.3 and 12p13.33 duplications.

• Mekkawy MK1, Mazen IM2, Kamel AK1, Vater I3, Zaki MS2.
• American journal of medical genetics. Part A.Am J Med Genet A.2016 Apr;170(4):1050-8. doi: 10.1002/ajmg.a.37523. Epub 2016 Jan 8.
• Many chromosomal rearrangements that lead to copy-number gains or losses have been shown to cause distinctive and recognizable clinical phenotypes. Conventional cytogenetic analysis can detect many, but not all, rearrangements depending on its power of resolution. The wide use of whole-genome array-
• PMID 26749249

• Somatic mosaicism underlies X-linked acrogigantism syndrome in sporadic male subjects.

• Daly AF1, Yuan B2, Fina F3, Caberg JH4, Trivellin G5, Rostomyan L1, de Herder WW6, Naves LA7, Metzger D8, Cuny T9, Rabl W10, Shah N11, Jaffrain-Rea ML12, Zatelli MC13, Faucz FR5, Castermans E4, Nanni-Metellus I14, Lodish M5, Muhammad A6, Palmeira L1, Potorac I15, Mantovani G16, Neggers SJ6, Klein M9, Barlier A17, Liu P14, Ouafik L18, Bours V4, Lupski JR19, Stratakis CA5, Beckers A20.
• Endocrine-related cancer.Endocr Relat Cancer.2016 Apr;23(4):221-33. doi: 10.1530/ERC-16-0082. Epub 2016 Mar 2.
• Somatic mosaicism has been implicated as a causative mechanism in a number of genetic and genomic disorders. X-linked acrogigantism (XLAG) syndrome is a recently characterized genomic form of pediatric gigantism due to aggressive pituitary tumors that is caused by submicroscopic chromosome Xq26.3 du
• PMID 26935837

Japanese Journal

• A Novel Diagnostic Method for Thyroid Follicular Tumors Based on Immunofluorescence Analysis of p53-Binding Protein 1 Expression: Detection of Genomic Instability

• Otsubo Ryota,Matsuda Katsuya,Mussazhanova Zhanna,Sato Ayako,Matsumoto Megumi,Yano Hiroshi,Oikawa Masahiro,Kondo Hisayoshi,Ito Masahiro,Miyauchi Akira,Hirokawa Mitsuyoshi,Nagayasu Takeshi,Nakashima Masahiro
• Thyroid 29(5), 657-665, 2019-05-13
• … Furthermore, the study clarified the relationship between 53BP1 NF and copy number aberrations (CNAs) based on array comparative genomic hybridization, a hallmark of genomic instability (GIN). … Thus, based on a comparison of these two indicators of GIN, 53BP1 NF (by IF) was better able to estimate the malignancy of FTs compared to CNA (by array comparative genomic hybridization). …
• NAID 120006646384

• Genome-wide discovery of chromosomal copy number variants in human amniotic cell using array-based comparative genomic hybridization

• LEE Sang Min
• 日本毒性学会学術年会 39.2(0), AP-225, 2012
• … However, conventional G-banding technique which is generally applied in CA detection has limit on exploit of copy number variants (CNVs) due to low resolution and tedious multiple processes. … Instead, array comparative genomic hybridization (aCGH) technology enabling incremented high-resolution can be considered as an alternative approach for improving prenatal diagnosis. …
• NAID 130005009170

• アレイ比較ゲノムデータ正規化手法 Combfit について

• 大羽 成征,富岡 伸元,大平 美紀 [他],石井 信
• 情報処理学会研究報告. BIO, バイオ情報学 9, 9-16, 2007-06-14
• マイクロアレイ技術に基づく染色体比較の方法としてアレイCGH法と呼ばれる手法が近年開発され、がんなどの細胞疾患の原因もしくは結果と目される染色体数変動を調べるのに使われている。通常のアレイCGHデータ解析では、DNA断片毎の複製数変動を「変動なし/増幅あり/減少あり」の3カテゴリーに分類しているが、近年の計測精度の改善によって、複製数変動に関するさらに定量的な解析が可能となってきた。そこで、我々は …
• NAID 110006343477

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★リンクテーブル★

リンク元	「比較ゲノムハイブリダイゼーション法」
関連記事	「hybridization」「comparative」「technique」「genomic」

「比較ゲノムハイブリダイゼーション法」

　　[★]

英

comparative genomic hybridization technique, comparative genomic hybridization method

同

comparative genomic hybridization法, CGH法

関

比較ゲノムハイブリダイゼーション, CGH

[show details]

比較ゲノムハイブリッド形成法 : 6 件
比較ゲノムハイブリダイゼーション法 : 40 件

「hybridization」

　　[★]

• n.

• ハイブリダイゼーション、ハイブリダイゼーション法、ハイブリッド形成法、(細胞や動物個体の)交雑、雑種形成、(化学)混成

関

cross、crossbred、crossbreeding、crossing、hybrid、hybridisation、hybridize、interbreed

　

「comparative」

　　[★]

• adj.

• 比較上の、比較による、比較的な
• 他と比較しての、相対的な、かなりの

関

comparably、comparatively、compare、comparison、weigh

　 　 　

「technique」

　　[★]

• n.

• 技術、手法、術式、技法、テクニック

関

method、skill、technic、technical

　 　

「genomic」

　　[★]

• ゲノムの

関

genome、genomically