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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2012/12/08 22:50:47」(JST)

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Comedocarcinoma is one kind of very early-stage breast cancer^[1]^[2] which demonstrates central necrosis.^[3] It is a type of ductal carcinoma in situ. Comedo carcinomas are non-infiltrating and intraductal tumors.

The duct will have characteristic necrotic tissue with calcification that feels cord-like. Squeezing the duct will yield inspissated material that is cheesy-like and similar in consistency to toothpaste.

References

This article incorporates public domain material from the U.S. National Cancer Institute document "Dictionary of Cancer Terms".

^ Yale: Cardiothoracic Imaging - Comedocarcinoma of the right breast
^ Definition: comedocarcinoma from Online Medical Dictionary
^ Pathology

External links

Comedo carcinoma entry in the public domain NCI Dictionary of Cancer Terms
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English Journal

Adenocarcinoma of the prostate with Gleason pattern 5 on core biopsy: frequency of diagnosis, morphologic subpatterns, and relation to pattern distribution based on the modified Gleason grading system.

Shah RB1, Tadros Y2.
Human pathology.Hum Pathol.2014 Nov;45(11):2263-9. doi: 10.1016/j.humpath.2014.07.012. Epub 2014 Aug 7.
Accurate recognition of Gleason pattern 5 (GP5) prostate adenocarcinoma (PCa) on core biopsy (NBX) is critical because it is associated with disease progression and the worst clinical outcome. We evaluated 1557 consecutive and prospectively collected NBXs to determine the frequency of diagnosis, mor
PMID 25228336

Immunohistochemical vascular factor expression in canine inflammatory mammary carcinoma.

Camacho L1, Peña L2, Gil AG3, Martín-Ruiz A3, Dunner S4, Illera JC3.
Veterinary pathology.Vet Pathol.2014 Jul;51(4):737-48. doi: 10.1177/0300985813503568. Epub 2013 Sep 18.
Human inflammatory breast carcinoma (IBC) and canine inflammatory mammary carcinoma (IMC) are considered the most malignant types of breast cancer. IMC has similar characteristics to IBC; hence, IMC has been suggested as a model to study the human disease. To compare the angiogenic and angioinvasive
PMID 24048323

Analysis of a new histological and molecular-based classification of canine mammary neoplasia.

Im KS1, Kim NH, Lim HY, Kim HW, Shin JI, Sur JH.
Veterinary pathology.Vet Pathol.2014 May;51(3):549-59. doi: 10.1177/0300985813498780. Epub 2013 Sep 3.
Canine mammary tumors (CMTs) are morphologically and biologically heterogeneous, prompting several attempts to classify such tumors on the basis of their histopathological characteristics. Recently, molecular-based analysis methods borrowed from human breast cancer research have also been applied to
PMID 24003019

Japanese Journal

人乳腺組織におけるestradiol-17β代謝の研究

藤井孝尚
日本内分泌学会雑誌 45(12), 1588-1598,1546, 1970
ヒト乳腺組織においてin vitroのestradiol-17βの代謝について検討した.代謝物としてestroneが同定されたがその他estriolと思われるpolarな代謝物が得られた.各種乳腺組織の代謝は質的に異ならなかつたが量的に異なつた.すなわち, 乳腺症, 授乳期乳腺, 乳癌転移巣で高く, 乳癌で低かつた.このestradiol-17βの代謝はin vitroに添加した10<SUP …
NAID 130001926435

異常乳頭分泌物の細胞診断

松田実,加藤みつよ
日本臨床細胞学会雑誌 8(1), 31-44, 1969-06-30
NAID 110001284537

異常乳頭分泌物の細胞診断

松田実,加藤みつよ
日本臨床細胞学会雑誌 8(1), 31-44, 1969
… The chromatin was most fine, however, difference of chromatin patterns may be seen in each different clusters and even in the cells of a cluster.<BR>The characteristics of desquamated cancer cells from comedocarcinoma were as follows:<BR>1) The cells usually present as single.<BR>2) The some of cells have round distinct cyto plasm, while others have poorly defined one.<BR>3) The nucleus varies in size, and abnormality was conspicuous. …
NAID 130003759079