同: c-onc

WordNet

relating to cells; "cellular walls"; "cellular physiology"
characterized by or divided into or containing cells or compartments (the smallest organizational or structural unit of an organism or organization); "the cellular construction of a beehive"; "any effective opposition to a totalitarian regime must be secretive and cellular"
a gene that disposes normal cells to change into cancerous tumor cells (同)transforming_gene

PrepTutorEJDIC

細胞の,細胞質の,細胞状の / 小室(小区画)のある / (生地など)目の透いている

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1. 大腸癌の分子遺伝学molecular genetics of colorectal cancer [show details]
…can be found elsewhere . Oncogenes are homologs of normal cellular genes that participate in cell growth pathways and cell cycle regulation. A mutational change in an oncogene leads to constitutive activation …
2. 慢性リンパ性白血病の病態生理pathobiology of chronic lymphocytic leukemia [show details]
… CD5+ B cells. In contrast to other proto-oncogenes, BCL2 has little or no ability to promote cell cycle progression or cell proliferation, but rather raises the cellular apoptotic threshold. It suppresses …
3. 慢性骨髄性白血病の細胞生物学および分子生物学cellular and molecular biology of chronic myeloid leukemia [show details]
…in the development of CML and has become a primary target for the treatment of this disorder. The cellular and molecular biology of CML will be reviewed here. The molecular genetics of this disorder, including … ability to transform cell lines and primary cells in vitro, demonstrating that it is a classical oncogene . The primary action of BCR-ABL1 in B-lymphoid progenitors appears to be stimulation of proliferation …
4. 前立腺癌の分子生物学molecular biology of prostate cancer [show details]
…elsewhere. Oncogenes are homologs of normal cellular genes in which a mutational change results in constitutive activation and gain of function. These mutations either accelerate cellular growth and/or …
5. 甲状腺結節および非髄様甲状腺癌におけるオンコジーンおよび腫瘍抑制遺伝子oncogenes and tumor suppressor genes in thyroid nodules and nonmedullary thyroid cancer [show details]
…to a clinically evident tumor mass. Unregulated cell division can result from mutations in both oncogenes and tumor suppressor genes. Although thyroid epithelial tumors arise from the same cell type, they …

English Journal

MicroRNA-30a as a prognostic factor in urothelial carcinoma of bladder inhibits cellular malignancy by antagonising Notch1.

Zhang C1, Ma X2, Du J1, Yao Z3, Shi T2, Ai Q2, Chen X1, Zhang Z1, Zhang X2, Yao X4.
BJU international.BJU Int.2016 Oct;118(4):578-89. doi: 10.1111/bju.13407. Epub 2016 Feb 21.
OBJECTIVE: To explore the relation between microRNA-30a (miR-30a) and Notch1, and to evaluate the potential prognostic role of miR-30a in invasive urothelial carcinoma of the bladder (UCB).PATIENTS AND METHODS: In all, 50 invasive UCB tissue specimens, along with the adjacent bladder tissue specimen
PMID 26775686

Cell Polarity Proteins in Breast Cancer Progression.

Rejon C1, Al-Masri M1, McCaffrey L1.
Journal of cellular biochemistry.J Cell Biochem.2016 Oct;117(10):2215-23. doi: 10.1002/jcb.25553. Epub 2016 Jun 30.
Breast cancer, one of the leading causes of cancer related death in women worldwide, is a heterogeneous disease with diverse subtypes that have different properties and prognoses. The developing mammary gland is a highly proliferative and invasive tissue, and some of the developmental programs may b
PMID 27362918

1,25-Dihydroxyvitamin D inhibits glutamine metabolism in Harvey-ras transformed MCF10A human breast epithelial cell.

Zhou X1, Zheng W2, Nagana Gowda GA3, Raftery D4, Donkin SS5, Bequette B6, Teegarden D7.
The Journal of steroid biochemistry and molecular biology.J Steroid Biochem Mol Biol.2016 Oct;163:147-56. doi: 10.1016/j.jsbmb.2016.04.022. Epub 2016 May 3.
Breast cancer is the second most common cancer among women in the US. The active form of vitamin D, 1,25-dihydroxyvitamin D (1,25(OH)2D), is proposed to inhibit cellular processes and to prevent breast cancer. The current studies investigated the effect of 1,25(OH)2D on glutamine metabolism during c
PMID 27154413