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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2014/08/21 23:48:35」(JST)
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Butobarbital
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|
| Systematic (IUPAC) name |
| 5-Butyl-5-ethyl-1,3-diazinane-2,4,6-trione |
| Clinical data |
| Trade names |
Soneryl |
| AHFS/Drugs.com |
International Drug Names |
| Legal status |
? |
| Routes |
Oral |
| Pharmacokinetic data |
| Metabolism |
Hepatic |
| Excretion |
Renal |
| Identifiers |
| CAS number |
77-28-1 Y |
| ATC code |
N05CA03 |
| PubChem |
CID 6473 |
| DrugBank |
DB01353 |
| ChemSpider |
6229 Y |
| UNII |
OHZ8QAW6YC Y |
| KEGG |
D02618 Y |
| ChEMBL |
CHEMBL404422 Y |
| Chemical data |
| Formula |
C10H16N2O3 |
| Mol. mass |
212.246 g/mol |
SMILES
- O=C1NC(=O)NC(=O)C1(CCCC)CC
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InChI
-
InChI=1S/C10H16N2O3/c1-3-5-6-10(4-2)7(13)11-9(15)12-8(10)14/h3-6H2,1-2H3,(H2,11,12,13,14,15) Y
Key:STDBAQMTJLUMFW-UHFFFAOYSA-N Y
|
| Y (what is this?) (verify) |
Butobarbital (BAN), also called butobarbitone or butethal, Soneryl, and Neonal,[1] is a hypnotic drug which is a barbiturate derivative. It was developed by Poulenc Brothers (now part of Rhône Poulenc) in 1921.[2]
References
- ^ International Drug Names
- ^ DE Patent 481129
|
Hypnotics/sedatives (N05C)
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GABAA
agonists/PAMs |
|
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GABAB
agonists |
- 1,4-Butanediol
- Aceburic acid
- GABOB
- GHB (Sodium oxybate)
- GBL
- GVL
|
|
H1 inverse
agonists |
| Antihistamines: |
- Captodiame
- Cyproheptadine
- Diphenhydramine
- Doxylamine
- Hydroxyzine
- Methapyrilene
- Pheniramine
- Promethazine
- Propiomazine
|
|
| Antidepressants |
- Tricyclic antidepressants
- Amitriptyline
- Doxepin
- Trimipramine, etc.
- Tetracyclic antidepressants
- Mianserin
- Mirtazapine, etc.
|
|
| Antipsychotics |
- Typical antipsychotics
- Chlorpromazine
- Thioridazine, etc.
- Atypical antipsychotics
- Olanzapine
- Quetiapine
- Risperidone, etc.
|
|
|
α1-Adrenergic
antagonists |
| Antidepressants |
- Serotonin antagonists and reuptake inhibitors
- Tricyclic antidepressants
- Amitriptyline
- Doxepin
- Trimipramine, etc.
- Tetracyclic antidepressants
|
|
| Antipsychotics |
- Typical antipsychotics
- Chlorpromazine
- Thioridazine, etc.
- Atypical antipsychotics
- Olanzapine
- Quetiapine
- Risperidone, etc.
|
|
| Others: |
|
|
|
α2-Adrenergic
agonists |
- 4-NEMD
- Clonidine
- Detomidine
- Dexmedetomidine
- Lofexidine
- Medetomidine
- Romifidine
- Tizanidine
- Xylazine
|
|
5-HT2A
antagonists |
| Antidepressants |
- Serotonin antagonists and reuptake inhibitors
- Tricyclic antidepressants
- Amitriptyline
- Doxepin
- Trimipramine, etc.
- Tetracyclic antidepressants
- Mianserin
- Mirtazapine, etc.
|
|
| Antipsychotics |
- Typical antipsychotics
- Chlorpromazine
- Thioridazine, etc.
- Atypical antipsychotics
- Olanzapine
- Quetiapine
- Risperidone, etc.
|
|
| Others: |
- Eplivanserin
- Niaprazine
- Pruvanserin
- Volinanserin
|
|
|
Melatonin
agonists |
- Agomelatine
- LY-156,735
- Melatonin
- Ramelteon
- Tasimelteon
|
|
Orexin
antagonists |
- Almorexant
- SB-334,867
- SB-408,124
- SB-649,868
- Suvorexant
- TCS-OX2-29
|
|
| Others |
- Acecarbromal
- Apronal
- Bromisoval
- Cannabidiol
- Carbromal
- Embutramide
- Evoxine
- Fenadiazole
- Gabapentin
- Kavalactones
- Mephenoxalone
- Opioids
- Passion flower
- Scopolamine
- UMB68
- Valnoctamide
|
|
English Journal
- Treatment gap for people living with epilepsy in Madagascar.
- Ratsimbazafy V1, Andrianabelina R, Randrianarisona S, Preux PM, Odermatt P.
- Tropical doctor.Trop Doct.2011 Jan;41(1):38-9. doi: 10.1258/td.2010.100254. Epub 2010 Dec 1.
- Using an indirect assessment technique we assessed the epilepsy treatment gap (ETG) in Madagascar. We estimate the ETG in Madagascar to be 92%. However, given the sociological, economic and sanitary conditions of the country, it is likely that the true ETG is even higher than our estimate. Our study
- PMID 21123488
- A study of the teratogenic and fetotoxic effects of large doses of barbital, hexobarbital and butobarbital used for suicide attempts by pregnant women.
- Timmermann G1, Czeizel AE, Bánhidy F, Acs N.
- Toxicology and industrial health.Toxicol Ind Health.2008 Feb-Mar;24(1-2):109-19. doi: 10.1177/0748233708089004.
- The teratogenic potential of barbiturates is debated. The objective of this study was to evaluate the effects of very large doses of different barbiturates, except phenobarbital and amobarbital, on fetal development in pregnant women who attempted suicide. These self-poisoned pregnant women were ide
- PMID 18818187
- A polymorph of butobarbital with two distinct hydrogen-bonding motifs.
- Gelbrich T1, Zencirci N, Griesser UJ.
- Acta crystallographica. Section C, Crystal structure communications.Acta Crystallogr C.2007 Dec;63(Pt 12):o751-3. Epub 2007 Nov 24.
- N-H...O bonding in a form of 5-butyl-5-ethylbarbituric acid (systematic name: 5-butyl-5-ethyl-1,3-diazinane-2,4,6-trione), C10H16N2O3, produces two distinct one-dimensional motifs, viz. tape and ladder. Both are different from the ribbon chain motif observed in two previously reported polymorphs of
- PMID 18057631
Related Links
- Structure, properties, spectra, suppliers and links for: Butobarbital, 77-28-1, butethal. ... Predicted data is generated using the US Environmental Protection Agency’s EPISuite , for more information see their website. Log Octanol ...
- Reviews about Butobarbital side effects, treatment effectiveness and alternative drugs. Positive and negative experiences from patients who took Butobarbital ... Discussed topics: Clonazepam Phenobarbital Secobarbital
Related Pictures
