WordNet

hormone secreted by the isles of Langerhans in the pancreas; regulates storage of glycogen in the liver and accelerates oxidation of sugar in cells

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1. 糖尿病におけるインスリン療法の一般原則 general principles of insulin therapy in diabetes mellitus
2. 2型糖尿病におけるインスリン療法 insulin therapy in type 2 diabetes mellitus
3. インスリン分泌および膵β細胞の機能 insulin secretion and pancreatic beta cell function
4. 糖尿病における吸入インスリン療法 inhaled insulin therapy in diabetes mellitus
5. インスリン受容体の構造および機能 structure and function of the insulin receptor

Braga RR1, Almeida L, Guerreiro LH, Tinoco P, Miranda KR, Braga CA, Gadelha AP, Garcia S, Lima LM.
Journal of liposome research.J Liposome Res.2015 Sep 4:1-11. [Epub ahead of print]
Amylin is a pancreatic hormone involved in the regulation of glucose metabolism and homeostasis. Restoration of the post-prandial and basal levels of human amylin in diabetic individuals is a key in controlling glycemia, controlling glucagon, reducing the insulin dose and increasing satiety, among o
PMID 26340033

Henquin JC1, Dufrane D2, Kerr-Conte J3, Nenquin M4.
American journal of physiology. Endocrinology and metabolism.Am J Physiol Endocrinol Metab.2015 Aug 11:ajpendo.00251.2015. doi: 10.1152/ajpendo.00251.2015. [Epub ahead of print]
The biphasic pattern of glucose-induced insulin secretion is altered in type2 diabetes. Impairment of the first phase is an early sign of β-cell dysfunction, but the underlying mechanisms are still unknown. Their identification through in vitro comparisons of islets from diabetic and control subjec
PMID 26264556

Effects of glucose, insulin and triiodothyroxine on leptin and leptin receptor expression and the effects of leptin on activities of enzymes related to glucose metabolism in grass carp (Ctenopharyngodon idella) hepatocytes.

Lu RH1, Zhou Y, Yuan XC, Liang XF, Fang L, Bai XL, Wang M, Zhao YH.
Fish physiology and biochemistry.Fish Physiol Biochem.2015 Aug;41(4):981-9. doi: 10.1007/s10695-015-0063-8. Epub 2015 May 8.
Leptin is an important regulator of appetite and energy expenditure in mammals, but its role in fish metabolism control is poorly understood. Our previous studies demonstrated that leptin has an effect on the regulation of food intake and energy expenditure as well as lipid metabolism (stimulation o
PMID 25952973

工藤宏仁,小山昌平,加藤俊祐,後藤尚
糖尿病 57(3), 175-180, 2014
68歳男性，病歴27年の2型糖尿病患者．2007年，67歳時にSU薬から切り替え，二相性インスリンアスパルトでの治療を開始した．当初コントロール良好だったが，インスリン治療開始から8ヵ月後，急にHbA1c 6 %台から8 %台へ悪化，連日の早朝低血糖と日中の著しい高血糖を認めた．IRI 4830 μU/ml，インスリン抗体結合率92.8 %と高値で，インスリン抗体による血糖変動と診断．インスリン製 …
NAID 130004511393

吉田瑛子,比嘉眞理子,土井綾乃 [他],吉藤歩,山下馨,一城貴政,大内博美,弘世貴久
東邦医学会雑誌 = Journal of Medical Society of Toho University 60(5), 276-281, 2013-09
… った．動脈血液ガス検査上アシドーシスであり，血中ケトン体および乳酸値も高値であった．DKA と乳酸性アシドーシスの合併を考え，直ちに生理食塩水の急速投与およびインスリン持続静注（continuous venous insulin infusion：CVII）療法を開始し血糖値，アシドーシスの改善を認めた．血液検査上炎症反応高値であり，腹部computed tomography（CT）検査から気腫性胆嚢炎と診断し，搬送4 時間後に緊急腹腔鏡下胆嚢摘出手術を施 …
NAID 120005346168

The Natural PPAR Agonist Linoleic Acid Stimulated Insulin Release in the Rat Pancreas

LAI Min-Chuan,TENG Tzu-Hua,YANG Chi
Journal of Veterinary Medical Science 75(11), 1449-1454, 2013
… Free fatty acids play an important role in regulating animal insulin secretion response. … Acute elevated free fatty acids increased animal insulin secretion and glucose-stimulated insulin secretion. … In the present study, we perfused the rat pancreas to explore the effect of unsaturated fatty acids on insulin secretion. …
NAID 130003362246