English Journal

Control of Polyamine Biosynthesis by Antizyme Inhibitor 1 is Important for Transcriptional Regulation of Arginine Vasopressin in the Male Rat Hypothalamus.

Greenwood MP1, Greenwood M, Paton JF, Murphy D.
Endocrinology.Endocrinology.2015 May 11:en20151074. [Epub ahead of print]
The polyamines spermidine and spermine are small cations present in all living cells. In the brain, these cations are particularly abundant in the neurons of the paraventricular (PVN) and supraoptic nuclei (SON) of the hypothalamus, which synthesise the neuropeptide hormones arginine vasopressin (AV
PMID 25961839

Molecular cloning and mRNA expression analysis of antizyme inhibitor 1 in the ovarian follicles of the Sichuan white goose.

Ma R1, Jiang D1, Kang B2, Bai L1, He H1, Chen Z1, Yi Z1.
Gene.Gene.2015 May 7. pii: S0378-1119(15)00553-3. doi: 10.1016/j.gene.2015.05.014. [Epub ahead of print]
Antizyme inhibitor 1 (Azin1) plays critical roles in various cellular pathways, including ornithine decarboxylase regulation, polyamine anabolism and uptake and cell proliferation. However, the molecular characteristics of the AZIN1 gene and its expression profile in goose tissues and ovarian follic
PMID 25959024

Influence of ornithine decarboxylase antizymes and antizyme inhibitors on agmatine uptake by mammalian cells.

Ramos-Molina B1, López-Contreras AJ, Lambertos A, Dardonville C, Cremades A, Peñafiel R.
Amino acids.Amino Acids.2015 May;47(5):1025-34. doi: 10.1007/s00726-015-1931-3. Epub 2015 Feb 6.
Agmatine (4-aminobutylguanidine), a dicationic molecule at physiological pH, exerts relevant modulatory actions at many different molecular target sites in mammalian cells, having been suggested that the administration of this compound may have therapeutic interest. Several plasma membrane transport
PMID 25655388

Japanese Journal

Molecular Basis for the Maintenance of Envelope Integrity in Selenomonas ruminantium : Cadaverine Biosynthesis and Covalent Modification into the Peptidoglycan Play a Major Role

児島征司,神尾好是
ビタミン 86(1), 1-12, 2012-01-25
… Its activity is tightly regulated by the antizyme-mediated proteolysis, a regulatory process generally found in eukaryotes. …
NAID 110009327876

Molecular Basis for the Maintenance of Envelope Integrity in Selenomonas ruminantium: Cadaverine Biosynthesis and Covalent Modification into the Peptidoglycan Play a Major Role

KOJIMA Seiji,KAMIO Yoshiyuki
Journal of Nutritional Science and Vitaminology 58(3), 153-160, 2012
… Lysine/ornithine decarboxylase (LDC/ODC), a PLP-dependent enzyme responsible for cadaverine synthesis in this bacterium, displays significant homology to the eukaryotic ODC but not to the general bacterial LDC nor ODC, and its activity is tightly regulated by antizyme-mediated proteolysis, a regulatory process generally found in eukaryotes. … ruminantium: its chemical structure, biosynthesis, and biological function, and (ii) cellular biosynthesis of cadaverine by LDC/ODC and its antizyme-mediated regulation. …
NAID 130002103038