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1. 妊娠における急性腎障害（急性腎不全） acute kidney injury acute renal failure in pregnancy
2. 虚血後（虚血性）の急性尿細管壊死の発症および病因 pathogenesis and etiology of postischemic ischemic acute tubular necrosis
3. 非乏尿性と乏尿性の急性尿細管壊死の比較 nonoliguric versus oliguric acute tubular necrosis
4. 腎臓の同種移植片機能不全の鑑別診断 differential diagnosis of renal allograft dysfunction
5. 世界中でのヘビ咬傷：マネージメント snakebites worldwide management

English Journal

Suppression of Mitochondrial Biogenesis through Toll-Like Receptor 4-Dependent Mitogen-Activated Protein Kinase Kinase/Extracellular Signal-Regulated Kinase Signaling in Endotoxin-Induced Acute Kidney Injury.

Smith JA1, Stallons LJ1, Collier JB1, Chavin KD1, Schnellmann RG2.
The Journal of pharmacology and experimental therapeutics.J Pharmacol Exp Ther.2015 Feb;352(2):346-57. doi: 10.1124/jpet.114.221085. Epub 2014 Dec 12.
Although disruption of mitochondrial homeostasis and biogenesis (MB) is a widely accepted pathophysiologic feature of sepsis-induced acute kidney injury (AKI), the molecular mechanisms responsible for this phenomenon are unknown. In this study, we examined the signaling pathways responsible for the
PMID 25503387

Evidence for the contribution of adult neurogenesis and hippocampal cell death in experimental cerebral malaria cognitive outcome.

de Miranda AS1, Brant F2, Campos AC2, Vieira LB3, Rocha NP4, Cisalpino D5, Binda NS6, Rodrigues DH7, Ransohoff RM8, Machado FS2, Rachid MA9, Teixeira AL10.
Neuroscience.Neuroscience.2015 Jan 22;284:920-33. doi: 10.1016/j.neuroscience.2014.10.062. Epub 2014 Nov 13.
Cognitive dysfunction is a major sign of cerebral malaria (CM). However, the underlying mechanisms of CM cognitive outcome remain poorly understood. A body of evidence suggests that adult neurogenesis may play a role in learning and memory processes. It has also been reported that these phenomena ca
PMID 25451296

Renoprotective Effects of Gamma-Aminobutyric Acid on Cisplatin-induced Acute Renal Injury in Rats.

Ali BH1, Al-Salam S, Al Za'abi M, Al Balushi KA, AlMahruqi AS, Beegam S, Al-Lawatia I, Waly MI, Nemmar A.
Basic & clinical pharmacology & toxicology.Basic Clin Pharmacol Toxicol.2015 Jan;116(1):62-8. doi: 10.1111/bcpt.12291. Epub 2014 Sep 13.
To investigate the effect of gamma-aminobutyric acid (GABA) on acute renal injury (ARI), we used here a rat model of acute tubular necrosis induced by the anticancer drug cisplatin (CP). GABA was given orally (100 or 500 mg/kg/day for ten consecutive days), and on the 6th day, some of the treated r
PMID 25052259

Short-term Menhaden Oil Rich Diet Changes Renal Lipid Profile in Acute Kidney Injury

Ossani Georgina P.,Denninghoff Valeria C.,Uceda Ana M. [他],Díaz Maria L.,Uicich Raúl,Monserrat Alberto J.
Journal of Oleo Science 64(5), 497-503, 2015
… Weanling male Wistar rats fed a choline-deficient diet develop acute kidney injury. … Choline-deficient rats fed vegetable oils showed renal cortical necrosis. …
NAID 130005067209

Ihara Katsuhito,Naito Shotaro,Okado Tomokazu,Rai Tatemitu,Mori Yutaro,Toda Takayuki,Uchida Shinichi,Sasaki Sei,Matsui Noriaki
Internal Medicine 54(1), 49-54, 2015
… Although the hemorrhage was eventually controlled, hepatic and renal dysfunction occurred, leading to acute kidney injury (AKI). …
NAID 130004902983

A comparative study of protective mechanisms of glycine and L-arginine against cisplatin-induced nephrotoxicity in rat renal cortical slices

Mahran Yasmen YFK,Khalifa Amani E,El-Demerdash Ebtehal
Drug Discoveries & Therapeutics 5(1), 32-40, 2011
… Amino acids exert nephroprotective effects in various forms of acute renal injury depending on their renal hemodynamic effects. … The present study was designed to elucidate and compare the role of non hemodynamic mechanisms in protective actions afforded by glycine and L-arginine against cisplatin (CDDP)-induced nephrotoxicity using rat renal cortical slices (RCS). …
NAID 130005054692