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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/05/24 16:13:29」(JST)
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Acetarsol
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Names |
Preferred IUPAC name
Acetarsone[citation needed]
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Systematic IUPAC name
(3-Acetamido-4-hydroxyphenyl)arsonic acid[1]
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Other names
3-Acetamido-4-hydroxyphenylarsonic acid[citation needed]
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Identifiers |
ATC code |
A07AX02
G01AB01, P01CD02, P51AD05 |
CAS Registry Number
|
97-44-9 N |
ChEMBL |
ChEMBL1330792 N |
ChemSpider |
1908 Y |
EC number |
202-582-3 |
InChI
-
InChI=1S/C8H10AsNO5/c1-5(11)10-7-4-6(9(13,14)15)2-3-8(7)12/h2-4,12H,1H3,(H,10,11)(H2,13,14,15) Y
Key: ODFJOVXVLFUVNQ-UHFFFAOYSA-N Y
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InChI=1/C8H10AsNO5/c1-5(11)10-7-4-6(9(13,14)15)2-3-8(7)12/h2-4,12H,1H3,(H,10,11)(H2,13,14,15)
Key: ODFJOVXVLFUVNQ-UHFFFAOYAX
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Jmol-3D images |
Image
Image |
KEGG |
D07110 Y |
MeSH |
Acetarsol |
PubChem |
1985 |
SMILES
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CC(=O)Nc1cc(ccc1O)[As](O)(O)=O
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CC(=O)NC1=CC(=CC=C1O)[As](O)(O)=O
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UNII |
806529YU1N Y |
UN number |
3465 |
Properties |
Chemical formula
|
C
8AsNH
10O
5 |
Molar mass |
275.0903 g mol−1 |
Hazards |
GHS pictograms |
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GHS signal word |
Danger |
GHS hazard statements
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H301, H331, H410 |
GHS precautionary statements
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P261, P273, P301+310, P311, P501 |
EU classification |
T N |
R-phrases |
R23/25, R50/53 |
S-phrases |
S20/21, S28, S45, S60, S61 |
Except where noted otherwise, data is given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
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N verify (what is: Y/N?) |
Infobox references |
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Acetarsol is an anti-infective.[2]
It was first discovered in 1921 at Pasteur Institute by Ernest Fourneau, and sold under the brand name Stovarsol (fourneau is the French word for stove).[3][4]
It has been given in suppositories.[5]
References
- ^ "acetarsol - PubChem Public Chemical Database". The PubChem Project. USA: National Center for Biotechnology Information.
- ^ Chen MY, Smith NA, Fox EF, Bingham JS, Barlow D (April 1999). "Acetarsol pessaries in the treatment of metronidazole resistant Trichomonas vaginalis". Int J STD AIDS 10 (4): 277–80. doi:10.1258/0956462991913943. PMID 12035784.
- ^ Éric Fouassier, Ces poisons qui guérissent, oct. 1996, p. 5.
- ^ Traité de chimie organique, sous la direction de Victor Grignard, Paul Baud, vol. 22, Masson, 1959, p. 1127-1130.
- ^ Gionchetti P, Rizzello F, Morselli C, Campieri M (October 2004). "Review article: problematic proctitis and distal colitis". Aliment. Pharmacol. Ther. 20 Suppl 4: 93–6. doi:10.1111/j.1365-2036.2004.02049.x. PMID 15352902.
Antidiarrheals, intestinal anti-inflammatory and anti-infective agents (A07)
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Rehydration |
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Intestinal anti-infectives |
- Antibiotics
- Amphotericin B
- Colistin
- Fidaxomicin
- Kanamycin
- Natamycin
- Neomycin
- Nystatin
- Paromomycin
- Polymyxin B
- Rifaximin
- Streptomycin
- Vancomycin
- Sulfonamides
- Phthalylsulfathiazole
- Succinylsulfathiazole
- Sulfaguanidine
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Intestinal adsorbents |
- Charcoal
- Bismuth
- Pectin
- Kaolin
- Crospovidone
- Attapulgite
- Diosmectite
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Antipropulsives (opioids) |
- Opium tincture (laudanum)
- Codeine
- Morphine
- Camphorated opium tincture (paregoric)
- crosses BBB: Diphenoxylate (Diphenoxylate/atropine)
- Difenoxin
- does not cross BBB: Loperamide
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Intestinal anti-inflammatory agents |
- corticosteroids acting locally
- Prednisolone
- Hydrocortisone
- Prednisone
- Betamethasone
- Tixocortol
- Budesonide
- Beclometasone
- antiallergic agents, excluding corticosteroids
- aminosalicylic acid and similar agents
- Sulfasalazine
- Mesalazine
- Olsalazine
- Balsalazide
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Antidiarrheal micro-organisms |
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Other antidiarrheals |
- Albumin tannate
- Ceratonia
- Crofelemer
- Octreotide
- Racecadotril
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Index of digestion
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Description |
- Anatomy
- Physiology
- Development
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Disease |
- Congenital
- Neoplasms and cancer
- Inflammatory bowel disease
- Gluten sensitivity
- Other
- Symptoms and signs
- Blood tests
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Treatment |
- Procedures
- Drugs
- anabolic steroids
- antacids
- diarrhoea and infection
- bile and liver
- functional gastrointestinal disorders
- laxatives
- peptic ulcer and reflux
- nausea and vomiting
- other
- Surgery
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Antiparasitics – antiprotozoal agents – Chromalveolate antiparasitics (P01)
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Alveo-
late |
Apicom-
plexa |
Conoidasida/
(Coccidiostats) |
Cryptosporidiosis |
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Isosporiasis |
- trimethoprim/sulfamethoxazole#
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Toxoplasmosis |
- pyrimethamine
- sulfadiazine
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Aconoidasida |
Malaria |
Individual
agents |
Hemozoin
inhibitors |
aminoquinolines |
- (4-): amodiaquine#
- chloroquine#
- Tafenoquine
- (8-): primaquine#
- pamaquine
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4-methanolquinolines |
- mefloquine#
- quinine#
- quinidine
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Other |
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Antifolates |
DHFR inhibitors
(antifols) |
- proguanil#
- chlorproguanil
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Sulfonamides |
- sulfadoxine
- sulfamethoxypyrazine
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Coformulation |
- sulfadoxine/pyrimethamine (SP)#
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Sesquiterpene
lactones |
- artemether#
- artesunate#
- dihydroartemisinin
- artemotil
- artemisinin
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Other |
- atovaquone (with proguanil as Malarone)
- tetracycline
- doxycycline#
- clindamycin
- pyronaridine
- piperaquine
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Combi-
nations |
Fixed-dose (coformulated) ACTs |
- artemether/lumefantrine#
- artesunate/amodiaquine (ASAQ)
- artesunate/mefloquine (ASMQ)
- dihydroartemisinin/piperaquine
- artesunate/pyronaridine
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Other combinations
(not co-formulated) |
- artesunate/SP
- artesunate/mefloquine
- quinine/tetracycline
- quinine/doxycycline
- quinine/clindamycin
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Babesiosis |
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Cilio-
phora |
- Balantidiasis: Tetracycline
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Hetero-
kont |
- Blastocystosis: Metronidazole
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- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
Index of protozoan infection
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Description |
- Alveolata
- Amoebozoa
- Excavata
- Protist
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Disease |
- Amoebozoa
- Chromalveolate
- Excavata
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Treatment |
- Drugs
- amoeboa
- chromalveolate
- excavata
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English Journal
- Unfolding and folding internal friction of β-hairpins is smaller than that of α-helices.
- Schulz JC1, Miettinen MS1, Netz RR1.
- The journal of physical chemistry. B.J Phys Chem B.2015 Apr 2;119(13):4565-74. doi: 10.1021/jp512056k. Epub 2015 Mar 18.
- By the forced unfolding of polyglutamine and polyalanine homopeptides in competing α-helix and β-hairpin secondary structures, we disentangle equilibrium free energetics from nonequilibrium dissipative effects. We find that α-helices are characterized by larger friction or dissipation upon unfold
- PMID 25741584
- Review article: the role of non-biological drugs in refractory inflammatory bowel disease.
- Ng SC1, Chan FK, Sung JJ.
- Alimentary pharmacology & therapeutics.Aliment Pharmacol Ther.2011 Feb;33(4):417-27. doi: 10.1111/j.1365-2036.2010.04541.x. Epub 2010 Dec 8.
- BACKGROUND: Up to one-third of patients with inflammatory bowel disease (IBD) do not respond to, or are intolerant of conventional immunosuppressive drugs. Although biological agents are alternative treatments, they may not be suitable or available to some patients.AIM: To review the evidence for us
- PMID 21138457
- [Researching the effectiveness and the relevancy of combined therapy with Polygynax and Pharmatex in the cases with proved HPV infection or suspicion of such infection].
- Hristamyan A.
- Akusherstvo i ginekologii︠a︡.Akush Ginekol (Sofiia).2011;50 Suppl 2:44-8.
- The HPV infection is the most frequent sexually transmitted disease. It can be estimated that approximately 80% of young women would be infected with it till their fiftieth anniversary. When there is a HPV infection in the zone of the external sexual organs and the introitus, in 90% of the cases, th
- PMID 22524141
Japanese Journal
- Destructive Effects of Various Drugs on Canine Filariae
- 小林 茂雄,大石 勇,久米 清治
- 日本獣医師会雑誌 17(2), 52-56, 1964
- … Acetarsol, an arsenical preparation, had no filaricidal effect on larvae and adults even when it was administered to dogs <I>per</I> …
- NAID 130003846906
Related Links
- Acetarsol is a medicine available in a number of countries worldwide. A list of US medications equivalent to Acetarsol is available on the Drugs.com website. ... Drugs.com provides accurate and independent information on more than ...
- acetarsol | C8H10AsNO5 | CID 1985 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more. ... National ...
Related Pictures
★リンクテーブル★
[★]
- 英
- acetarsol
- 同
- アセタルゾン acetarsone