English Journal

Haanstra JR1, González-Marcano EB2, Gualdrón-López M3, Michels PA4.
Biochimica et biophysica acta.Biochim Biophys Acta.2016 May;1863(5):1038-48. doi: 10.1016/j.bbamcr.2015.09.015. Epub 2015 Sep 16.
Peroxisomes of organisms belonging to the protist group Kinetoplastea, which include trypanosomatid parasites of the genera Trypanosoma and Leishmania, are unique in playing a crucial role in glycolysis and other parts of intermediary metabolism. They sequester the majority of the glycolytic enzymes
PMID 26384872

Leucine-684: A conserved residue of an AMP-acetyl CoA synthetase (AceCS) from Leishmania donovani is involved in substrate recognition, catalysis and acetylation.

Soumya N1, Tandan H2, Damre MV2, Gangwal RP2, Sangamwar AT2, Singh S3.
Gene.Gene.2016 Apr 15;580(2):125-33. doi: 10.1016/j.gene.2016.01.011. Epub 2016 Jan 12.
AMP-acetyl CoA synthetase (AMP-AceCS) is a key enzyme which catalyzes the activation of acetate to acetyl CoA, an important intermediate at the cross roads of various anabolic and catabolic pathways. Multiple sequence alignment of Leishmania donovani AceCS with other organisms revealed the presence
PMID 26794803

Garcia MN1, Woc-Colburn L1, Rossmann SN2, Townsend RL3, Stramer SL3, Bravo M4, Kamel H4, Beddard R5, Townsend M6, Oldham R6, Bottazzi ME1, Hotez PJ1, Murray KO1.
Epidemiology and infection.Epidemiol Infect.2016 Apr;144(5):1010-3. doi: 10.1017/S0950268814002234. Epub 2014 Aug 29.
Chagas disease is an important emerging disease in Texas that results in cardiomyopathy in about 30% of those infected with the parasite Trypanosoma cruzi. Between the years 2008 and 2012, about 1/6500 blood donors were T. cruzi antibody-confirmed positive. We found older persons and minority popula
PMID 25170765