ポット病
WordNet
- an impairment of health or a condition of abnormal functioning
- caused by or altered by or manifesting disease or pathology; "diseased tonsils"; "a morbid growth"; "pathologic tissue"; "pathological bodily processes" (同)morbid, pathologic, pathological
- a European river; flows into the Adriatic Sea (同)Po River
PrepTutorEJDIC
- (体の)『病気』,疾患 / (精神・道徳などの)病気,病弊
- 女性の話術芸人 =diseur
- 病気にかかった / 病的な,不健全な(morbid)
- poloniumの化学記号
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/09/15 01:38:41」(JST)
[Wiki en表示]
"Pott's disease" redirects here. It is not to be confused with Postural orthostatic tachycardia syndrome, also known as "POTS".
| Pott disease |
| Classification and external resources |
| Specialty |
rheumatology |
| ICD-10 |
A18.0, M49.0 |
| ICD-9-CM |
015.0 |
| MeSH |
D014399 |
Tuberculosis of the spine in an Egyptian mummy
Pott disease or Pott's disease is a form of tuberculosis that occurs outside of the lungs whereby disease is seen in the spinal vertebrae.[1] Tuberculosis can affect several tissues outside of the lungs including the spine, a kind of tuberculous arthritis of the intervertebral joints. The disease is named after Percivall Pott (1714–1788), a British surgeon. The lower thoracic and upper lumbar vertebrae are the areas of the spine most often affected. The formal name for the disease is tuberculous spondylitis and it is most commonly localized in the thoracic portion of the spine.
Pott’s disease results from haematogenous spread of tuberculosis from other sites, often the lungs. The infection then spreads from two adjacent vertebrae into the adjoining intervertebral disc space. If only one vertebra is affected, the disc is normal, but if two are involved, the disc, which is avascular, cannot receive nutrients and collapses. The disc tissue dies and is broken down by caseation, leading to vertebral narrowing and eventually to vertebral collapse and spinal damage. A dry soft tissue mass often forms and superinfection is rare.
Contents
- 1 Diagnosis
- 2 Prevention
- 3 Management
- 4 Prognosis
- 5 Cultural references
- 6 References
- 7 External links
Diagnosis
- – CBC: leukocytosis
- – Elevated erythrocyte sedimentation rate: >100 mm/h
- – Tuberculin skin test (purified protein derivative [PPD]) results are positive in 84–95% of patients with Pott disease who are not infected with HIV.
A girl from Oklahoma, who has been affected by bone tuberculosis, 1935
- – Radiographic changes associated with Pott disease present relatively late. The following are radiographic changes characteristic of spinal tuberculosis on plain radiography:
- Lytic destruction of anterior portion of vertebral body
- Increased anterior wedging
- Collapse of vertebral body
- Reactive sclerosis on a progressive lytic process
- Enlarged psoas shadow with or without calcification
- – Additional radiographic findings may include the following:
- Vertebral end plates are osteoporotic.
- Intervertebral disks may be shrunk or destroyed.
- Vertebral bodies show variable degrees of destruction.
- Fusiform paravertebral shadows suggest abscess formation.
- Bone lesions may occur at more than one level.
- Bone scan
- CT of the spine
- Bone biopsy
- MRI
Prevention
Controlling the spread of tuberculosis infection can prevent tuberculous spondylitis and arthritis. Patients who have a positive PPD test (but not active tuberculosis) may decrease their risk by properly taking medicines to prevent tuberculosis. To effectively treat tuberculosis, it is crucial that patients take their medications exactly as prescribed.
Management
- Non-operative – antituberculous drugs
- Analgesics
- Immobilization of the spine region using different types of braces and collars
- Surgery may be necessary, especially to drain spinal abscesses or debride bony lesions fully or to stabilize the spine. A 2007 review found only just two randomized clinical trials with at least one year-follow up found which compared chemotherapy plus surgery with chemotherapy alone for treating people diagnosed with active tuberculosis of the spine. As such there is no high grade evidence but the results of this study indicates that surgery should not be recommended routinely and clinicians have to selectively judge and decide on which patients to operate.[2]
- Thoracic spinal fusion with or without instrumentation as a last resort
- Physical therapy for pain-relieving modalities, postural education and teaching a home exercise program for strength and flexibility
Prognosis
- Vertebral collapse resulting in kyphosis
- Spinal cord compression
- Sinus formation
- Paraplegia (so called Pott's paraplegia)
Cultural references
- The Passionist saint Gemma Galgani suffered from tuberculosis of the spine.
- The fictional Hunchback of Notre Dame had a gibbous deformity (humpback) similar to the type caused by tuberculosis.
- In Henrik Ibsen's play "A Doll's House," Dr. Rank suffers from "consumption of the spine."
- Jocelin, the Dean who wanted a spire on his cathedral in William Golding's "The Spire" probably suffered and died as a result of this disease.
- English poets Alexander Pope and William Ernest Henley both suffered from Pott's disease.
- Anna Roosevelt Cowles, sister of president Theodore Roosevelt, suffered from Pott's disease.
- Chick Webb, swing era drummer and band leader, was afflicted with tuberculosis of the spine as a child, which left him hunchbacked.
- The Sicilian mafia boss Luciano Leggio had Pott's disease and wore a brace.
- Morton, the railroad magnate in Once Upon a Time in the West, suffers from the disease and needs crutches to walk.
- Writer Max Blecher had Pott's disease.
- Marxist thinker and Communist leader Antonio Gramsci suffered from Pott's disease, probably due to the bad conditions of his incarceration in fascist Italy during the 1930s.
- Italian writer, poet and philosopher Giacomo Leopardi suffered from this disease.
- It features prominently in the book This Is a Soul, which chronicles the work of American physician Rick Hodes in Ethiopia.
- Imogen in the novella "The Princess with the Golden Hair," part of Memoirs of Hecate County by Edmund Wilson (1946) has Pott's disease.
- Jane Addams, social activist and Nobel Peace Prize winner, had Pott's disease.
References
- ^ "Extrapulmonary Tuberculosis". TB Symptoms. 2013-01-18. Retrieved 2013-07-11.
- ^ Jutte PC, van Loenhout-Rooyackers JH. Routine surgery in addition to chemotherapy for treating spinal tuberculosis. Cochrane Database of Systematic Reviews 2006, Issue 1. Art. No.: CD004532. DOI: 10.1002/14651858.CD004532.pub2. http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD004532.pub2/abstract
External links
- Pott Disease — Tuberculous Spondylitis (medical article with MRI picture), eMedicine .
- "Tuberculous arthritis", MedlinePlus, USA: NIH . Public domain.
- Pott disease
- Pott's Disease of the Thoracic Spine
|
Gram-positive bacterial infection: Actinobacteria (primarily A00–A79, 001–041, 080–109)
|
|
| Actinomycineae |
| Actinomycetaceae |
- Actinomyces israelii
- Actinomycosis
- Cutaneous actinomycosis
- Tropheryma whipplei
- Arcanobacterium haemolyticum
- Arcanobacterium haemolyticum infection
- Actinomyces gerencseriae
|
|
| Propionibacteriaceae |
|
|
|
| Corynebacterineae |
| Mycobacteriaceae |
M. tuberculosis/
M. bovis |
- Tuberculosis: Ghon focus/Ghon's complex
- Pott disease
- brain
- Tuberculous lymphadenitis
- Tuberculous cervical lymphadenitis
- cutaneous
- Scrofuloderma
- Erythema induratum
- Lupus vulgaris
- Prosector's wart
- Tuberculosis cutis orificialis
- Tuberculous cellulitis
- Tuberculous gumma
- Lichen scrofulosorum
- Tuberculid
- Papulonecrotic tuberculid
- Primary inoculation tuberculosis
- Miliary
- Tuberculous pericarditis
- Urogenital tuberculosis
- Multi-drug-resistant tuberculosis
- Extensively drug-resistant tuberculosis
|
|
| M. leprae |
- Leprosy: Tuberculoid leprosy
- Borderline tuberculoid leprosy
- Borderline leprosy
- Borderline lepromatous leprosy
- Lepromatous leprosy
- Histoid leprosy
|
|
| Nontuberculous |
| R1: |
|
|
| R2: |
|
|
| R3: |
- M. avium complex/Mycobacterium avium/Mycobacterium intracellulare/MAP
- M. ulcerans
- M. haemophilum
|
|
| R4/RG: |
- M. fortuitum
- M. chelonae
- M. abscessus
|
|
|
|
| Nocardiaceae |
- Nocardia asteroides/Nocardia brasiliensis
- Rhodococcus equi
|
|
| Corynebacteriaceae |
- Corynebacterium diphtheriae
- Corynebacterium minutissimum
- Corynebacterium jeikeium
- Group JK corynebacterium sepsis
|
|
|
| Bifidobacteriaceae |
|
|
|
Index of bacterial disease
|
|
| Description |
|
|
| Disease |
- Gram-positive firmicutes
- Gram-positive actinobacteria
- Gram-negative proteobacteria
- Gram-negative non-proteobacteria
- Cholera
- Tuberculosis
|
|
| Treatment |
- Antibiotics
- cell wall
- nucleic acid
- mycobacteria
- protein synthesis
- other
- Antibodies
|
|
|
|
Spinal disease (M40–M54, 720–724, 737)
|
|
| Deforming |
| Spinal curvature |
- Kyphosis
- Lordosis
- Scoliosis
|
|
| Other |
- Scheuermann's disease
- Torticollis
|
|
|
| Spondylopathy |
| inflammatory |
- Spondylitis
- Sacroiliitis
- Discitis
- Spondylodiscitis
- Pott disease
|
|
| non inflammatory |
- Spondylosis
- Spondylolysis
- Spondylolisthesis
- Spinal stenosis
- Facet syndrome
|
|
|
| Back pain |
- Neck pain
- Upper back pain
- Low back pain
- Radiculopathy
|
|
| Intervertebral disc disorder |
- Schmorl's nodes
- Degenerative disc disease
- Spinal disc herniation
- Facet joint arthrosis
|
|
|
Index of joint
|
|
| Description |
- Anatomy
- head and neck
- cranial
- arms
- torso and pelvis
- legs
- bursae and sheathes
- Physiology
|
|
| Disease |
- Arthritis
- acquired
- back
- childhood
- soft tissue
- Congenital
- Injury
- Symptoms and signs
- Examination
|
|
| Treatment |
- Procedures
- Drugs
- rheumatoid arthritis
- gout
- topical analgesics
|
|
|
UpToDate Contents
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- 1. 骨格系結核 skeletal tuberculosis
- 2. 中枢神経系結核 central nervous system tuberculosis
- 3. 脊髄に影響を与える疾患 disorders affecting the spinal cord
- 4. 小児における後天性斜頚 acquired torticollis in children
- 5. 深頸部の感染症 deep neck space infections
English Journal
- Positron emission tomography/computed tomography images of pulmonary and spinal tuberculosis.
- Gao X1, Yang ZH2, Yuan Z3, Ye XD4.
- European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.Eur J Cardiothorac Surg.2014 Aug;46(2):e34. doi: 10.1093/ejcts/ezu212. Epub 2014 May 16.
- PMID 24835666
- Update on the molecular pathogenesis and targeted approaches of mantle cell lymphoma (MCL) - summary of the 12th annual conference of the EUROPEAN MCL NETWORK.
- Dreyling M, Amador V, Callanan M, Jerkeman M, Gouill SL, Pott C, Rule S, Zaja F; for the European MCL Network.
- Leukemia & lymphoma.Leuk Lymphoma.2014 Jul 11:1-26. [Epub ahead of print]
- Abstract Mantle cell lymphoma (MCL) is a distinct subtype of malignant lymphoma which is characterized by the chromosomal translocation t(11;14)(q13;q32) resulting in constitutional overexpression of cyclin D1 and cell cycle dysregulation in almost all cases. Clinically, mantle cell lymphoma MCL sho
- PMID 25015778
- Determinants of PCR performance (Xpert MTB/RIF), including bacterial load and inhibition, for TB diagnosis using specimens from different body compartments.
- Theron G1, Peter J1, Calligaro G1, Meldau R1, Hanrahan C2, Khalfey H1, Matinyenya B1, Muchinga T1, Smith L1, Pandie S3, Lenders L1, Patel V4, Mayosi BM3, Dheda K5.
- Scientific reports.Sci Rep.2014 Jul 11;4:5658. doi: 10.1038/srep05658.
- The determinants of Xpert MTB/RIF sensitivity, a widely used PCR test for the diagnosis of tuberculosis (TB) are poorly understood. We compared culture time-to-positivity (TTP; a surrogate of bacterial load), MTB/RIF TB-specific and internal positive control (IPC)-specific CT values, and clinical ch
- PMID 25014250
Japanese Journal
- 史的研究 臥床から六年の経過で死亡した結核性脊椎炎の一例(明治期の史的考察)
- Comparison of Anterior Instrumentation Systems and the Results of Minimum 5 Years Follow - up in the Treatment of Tuberculosis Spondylitis
- Benli I. Teoman,Alanay Ahmet,Akalin Serdar,Kis Mahmut,Acaroglu Emre,Ates.Bulent,Aydin Erbil
- The Kobe journal of the medical sciences 50(5/6), 167-180, 2004
- … This study reports on the surgical results of 59 patientswith Pott's disease that had anterior radical debridement and anterior fusion andanterior instrumentation with 5 years follow - up. …
- NAID 110001874633
Related Links
- This article includes a list of references, related reading or external links, but its sources remain unclear because it lacks inline citations. Please improve ... Pott disease or Pott's disease is a form of tuberculosis that occurs outside ...
- Pott disease, also known as tuberculous spondylitis, is one of the oldest demonstrated diseases of humankind, having been documented in spinal remains from the Iron Age in Europe and in ancient mummies from Egypt ...
Related Pictures
★リンクテーブル★
[★]
- 英
- Pott's disease, Pott disease
- 同
- Pott病、脊椎結核 spinal tuberculosis spondylitis tuberculosa、脊椎カリエス spinal caries
- 関
- tuberculosis spinal
-Pott病
[★]
- 疾患：illnessより厳密な概念。「ある臓器に明確な障害が確認され、それによって症状が出ているとはっきり説明できる場合」 (PSY.9)
- 特定の原因、病態生理、症状、経過、予後、病理組織所見が全てそろった場合 (PSY.9)
- something that is very wrong with people's attitudes, way of life or with society.
- 関
- ail、ailment、disease entity、disorder、ill、illness、malady、sick、sickness
- disease ≠ illness ≠ disorder
[★]
ポロニウム polonium