WordNet

any of a large group of nitrogenous organic compounds that are essential constituents of living cells; consist of polymers of amino acids; essential in the diet of animals for growth and for repair of tissues; can be obtained from meat and eggs and milk and legumes; "a diet high in protein"
Scottish explorer in Africa (1771-1806) (同)Mungo Park

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1. パーキンソン病の病因および発症機序 etiology and pathogenesis of parkinson disease
2. ジストニアの分類および評価 classification and evaluation of dystonia
3. パーキンソン病による認識機能障害および認知症 cognitive impairment and dementia in parkinson disease
4. ハンセン病の疫学、微生物学、臨床症状、および診断 epidemiology microbiology clinical manifestations and diagnosis of leprosy
5. プロテインＳ欠乏症 protein s deficiency

Involvement of PINK1/Parkin-mediated mitophagy in AGE-induced cardiomyocyte aging.

Zha Z1, Wang J2, Wang X1, Lu M1, Guo Y3.
International journal of cardiology.Int J Cardiol.2016 Nov 9. pii: S0167-5273(16)33621-X. doi: 10.1016/j.ijcard.2016.11.161. [Epub ahead of print]
CONTEXT AND OBJECTIVES: Advanced glycation end products (AGEs) can induce senescence in cardiomyocytes. However, its underlying molecular mechanisms remain unknown.METHODS: Neonatal rat cardiomyocytes were incubated with AGEs, and cellular senescence was evaluated by senescence-associated beta-galac
PMID 27839819

Merzetti EM1, Staveley BE2.
Genetics and molecular research : GMR.Genet Mol Res.2016 Nov 3;15(4). doi: 10.4238/gmr15048934.
Mitochondrial destruction leads to the formation of reactive oxygen species, increases cellular stress, causes apoptotic cell death, and involves a cascade of proteins including PARKIN, PINK1, and Mitofusin2. Mitochondrial biogenesis pathways depend upon the activity of the protein PGC-1α. These tw
PMID 27819722

Carnosic acid protects SH-SY5Y cells against 6-hydroxydopamine-induced cell death through upregulation of parkin pathway.

Lin CY1, Tsai CW1, Tsai CW2.
Neuropharmacology.Neuropharmacology.2016 Nov;110(Pt A):109-17. doi: 10.1016/j.neuropharm.2016.04.017. Epub 2016 Apr 16.
Parkin is a Parkinson's disease (PD)-linked gene that plays an important role in the ubiquitin-proteasome system (UPS). This study explored whether carnosic acid (CA) from rosemary protects against 6-hydroxydopamine (6-OHDA)-induced neurotoxicity via upregulation of parkin in vivo and in vitro. We
PMID 27091487

2P129 Generalized Bornモデルによる蛋白質-蛋白質間相互作用計算の重要パラメータ(07. 水・水和/電解質,ポスター,第52回日本生物物理学会年会(2014年度))

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