English Journal

Conversion of cheese whey into poly(3-hydroxybutyrate-co-3-hydroxyvalerate) by Haloferax mediterranei.

Pais J1, Serafim LS2, Freitas F3, Reis MA1.
New biotechnology.N Biotechnol.2016 Jan 25;33(1):224-30. doi: 10.1016/j.nbt.2015.06.001. Epub 2015 Jun 29.
Haloferax mediterranei was cultivated in highly saline medium using cheese whey as the substrate for the production of poly(3-hydroxybutyrate-co-3-hydroxyvalerate), P(3HB-co-3HV). Acid hydrolysis provided a simple inexpensive method to obtain a cheese whey hydrolysate that was used for cultivation o
PMID 26134839

Mass production of C50 carotenoids by Haloferax mediterranei in using extruded rice bran and starch under optimal conductivity of brined medium.

Chen CW1, Hsu SH2, Lin MT2, Hsu YH2.
Bioprocess and biosystems engineering.Bioprocess Biosyst Eng.2015 Dec;38(12):2361-7. doi: 10.1007/s00449-015-1471-y. Epub 2015 Sep 15.
Microbial carotenoids have potentially healthcare or medical applications. Haloferax mediterranei was difficult to economically grow into a large quantities as well as producing a valuable pigment of carotenoids. This study reports a novel investigation into the optimal conductivity on the mass prod
PMID 26373421

Activation of a dormant replication origin is essential for Haloferax mediterranei lacking the primary origins.

Yang H1,2, Wu Z1, Liu J1, Liu X1, Wang L1, Cai S1, Xiang H1.
Nature communications.Nat Commun.2015 Sep 16;6:8321. doi: 10.1038/ncomms9321.
The use of multiple origins for chromosome replication has been demonstrated in archaea. Similar to the dormant origins in eukaryotes, some potential origins in archaea appear to be inactive during genome replication. We have comprehensively explored the origin utilization in Haloferax mediterranei.
PMID 26374389