WordNet

link together; "can we couple these proposals?" (同)couple on, couple up
two items of the same kind (同)pair, twosome, twain, brace, span, yoke, couplet, distich, duo, duet, dyad, duad
a small indefinite number; "hes coming for a couple of days"
a pair of people who live together; "a married couple from Chicago" (同)mates, match
a pair who associate with one another; "the engaged couple"; "an inseparable twosome" (同)twosome, duo, duet
(physics) something joined by two equal and opposite forces that act along parallel lines
any of a large group of nitrogenous organic compounds that are essential constituents of living cells; consist of polymers of amino acids; essential in the diet of animals for growth and for repair of tissues; can be obtained from meat and eggs and milk and legumes; "a diet high in protein"
a cellular structure that is postulated to exist in order to mediate between a chemical agent that acts on nervous tissue and the physiological response
a unit of force equal to the force exerted by gravity; used to indicate the force to which a body is subjected when it is accelerated (同)gee, g-force
an enzyme that catalyzes the conversion of a proenzyme to an active enzyme

PrepTutorEJDIC

(同種類の物が)『2個』《+『of』+『名』》 / 『夫婦』,男女一組 / 《話》(…の)いくらか,少数《+『of』+『名』》 / …'を'『つなぎ合わせる』;(…に)…'を'連結する《+『名』+『to』(『with』)+『名』》 / …'を'(…と)関連づける《+『名』+『with』(『to』)+『名』》 / …'を'結婚させる,〈動物〉'を'つがわせる / 〈動物〉交尾する
蛋白(たんばく)質
=sense organ / 受信装置

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1. ペプチドホルモンのシグナル伝達および調節 peptide hormone signal transduction and regulation
2. 収縮能障害による心不全におけるβブロッカー使用の理論的根拠および臨床試験 rationale for and clinical trials of beta blockers in heart failure due to systolic dysfunction
3. 喘息におけるβ刺激剤：長期使用に関する議論 beta agonists in asthma controversy regarding chronic use
4. 複合免疫不全 combined immunodeficiencies
5. 血管作動性腸管ポリペプチド vasoactive intestinal polypeptide

Endothelial g protein-coupled receptor kinase 2 regulates vascular homeostasis through the control of free radical oxygen species.

Ciccarelli M, Sorriento D, Franco A, Fusco A, Del Giudice C, Annunziata R, Cipolletta E, Monti MG, Dorn GW 2nd, Trimarco B, Iaccarino G.SourceFrom the Department of Medicine and Surgery, University of Salerno, Salerno, Italy (M.C., E.C., G.l.); Department of Pharmacology, Center for Translational Medicine, Temple University, Philadelphia, PA (M.C.); Department of Biomedical Sciences, University of Naples Federico II, Naples, Italy (D.S., A.F., C.D.G., R.A., M.G.M., B.T.); Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO (G.W.D.); and IRCCS Multimedica, Milan, Italy (G.I.).
Arteriosclerosis, thrombosis, and vascular biology.Arterioscler Thromb Vasc Biol.2013 Oct;33(10):2415-24. doi: 10.1161/ATVBAHA.113.302262. Epub 2013 Aug 15.
OBJECTIVE: The role of endothelial G protein-coupled receptor kinase 2 (GRK2) was investigated in mice with selective deletion of the kinase in the endothelium (Tie2-CRE/GRK2(fl/fl)).APPROACH AND RESULTS: Aortas from Tie2-CRE/GRK2(fl/fl) presented functional and structural alterations as compared wi
PMID 23950144

Desensitization and Internalization of Endothelin Receptor A: Impact of G Protein-coupled Receptor Kinase 2-mediated Phosphorylation.

Gärtner F, Seidel T, Schulz U, Gummert J, Milting H.SourceE. & H. Klessmann Institute for Cardiovascular Research & Development, Heart and Diabetes Center NRW;
The Journal of biological chemistry.J Biol Chem.2013 Sep 24. [Epub ahead of print]
Endothelin receptor A (ETA), a G protein-coupled receptor (GPCR), mediates signaling of endothelins, which is regulated by GPCR kinase 2 (GRK2). Three Ser and seven Thr residues recently proven to be phospho-acceptor sites are located in the C-terminal extremity (CTE) of the receptor following its p
PMID 24064210

Protein Kinase A and Phosphodiesterase-4D3 Binding to Coding Polymorphisms of Cardiac Muscle Anchoring Protein (mAKAP).

Rababa'h A, Craft JW Jr, Wijaya CS, Atrooz F, Fan Q, Singh S, Guillory AN, Katsonis P, Lichtarge O, McConnell BK.SourceDepartment of Pharmacological and Pharmaceutical Sciences, University of Houston, Texas Medical Center, Houston, TX 77204, USA.
Journal of molecular biology.J Mol Biol.2013 Sep 23;425(18):3277-88. doi: 10.1016/j.jmb.2013.06.014. Epub 2013 Jun 25.
Protein kinase A (PKA) substrate phosphorylation is facilitated through its co-localization with its signaling partner by A-kinase anchoring proteins (AKAPs). mAKAP (muscle-selective AKAP) localizes PKA and its substrates such as phosphodiesterase-4D3 (PDE4D3), ryanodine receptor, and protein phosph
PMID 23806656

AM251 Suppresses Epithelial-Mesenchymal Transition of Renal Tubular Epithelial Cells

Cytoplasmic kinases downstream of GPR30 suppress gonadotropin-releasing hormone (GnRH)-induced luteinizing hormone secretion from bovine anterior pituitary cells