WordNet
- first in order of importance; "the alpha male in the group of chimpanzees"; "the alpha star in a constellation is the brightest or main star"
- the 1st letter of the Greek alphabet
- the beginning of a series or sequence; "the Alpha and Omega, the first and the last, the beginning and the end"--Revelations
- early testing stage of a software or hardware product; "alpha version"
- the 17th letter of the Roman alphabet (同)q
- a unit of force equal to the force exerted by gravity; used to indicate the force to which a body is subjected when it is accelerated (同)gee, g-force
- the 7th letter of the Roman alphabet (同)g
- any high mountain
PrepTutorEJDIC
- アルファ(ギリシア語アルファベットの第1字A,α;英語のA,aに相当) / アルファ星(星座の主星)
- (チェスの)queen
- 高山,高峰
UpToDate Contents
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- 1. α-1アンチトリプシン欠乏の治療 treatment of alpha 1 antitrypsin deficiency
- 2. 昇圧剤および強心剤の使用 use of vasopressors and inotropes
- 3. αサラセミアの病態生理 pathophysiology of alpha thalassemia
- 4. Anesthesia for patients with thyroid disease
- 5. 下肢末梢動脈疾患の症状を治療するための試験的治療 investigational therapies for treating symptoms of lower extremity peripheral artery disease
English Journal
- The somatic GNAQ mutation c.548G>A (p.R183Q) is consistently found in Sturge-Weber syndrome.
- Nakashima M1, Miyajima M2, Sugano H2, Iimura Y2, Kato M3, Tsurusaki Y1, Miyake N1, Saitsu H1, Arai H2, Matsumoto N1.
- Journal of human genetics.J Hum Genet.2014 Dec;59(12):691-3. doi: 10.1038/jhg.2014.95. Epub 2014 Nov 6.
- Sturge-Weber syndrome (SWS) is a neurocutaneous disorder characterized by capillary malformation (port-wine stains), and choroidal and leptomeningeal vascular malformations. Previously, the recurrent somatic mutation c.548G>A (p.R183Q) in the G-α q gene (GNAQ) was identified as causative in SWS
- PMID 25374402
- Angiotensin II induces DNA damage via AT1 receptor and NADPH oxidase isoform Nox4.
- Fazeli G1, Stopper H, Schinzel R, Ni CW, Jo H, Schupp N.
- Mutagenesis.Mutagenesis.2012 Nov;27(6):673-81. doi: 10.1093/mutage/ges033. Epub 2012 Jul 27.
- Epidemiological studies revealed increased renal cancer incidences and higher cancer mortalities in hypertensive individuals. Activation of the renin-angiotensin-aldosterone system leads to the formation of reactive oxygen species (ROS). In vitro, in renal cells, and ex vivo, in the isolated perfuse
- PMID 22844079
- A role for intracellular calcium downstream of G-protein signaling in undifferentiated human embryonic stem cell culture.
- Ermakov A1, Pells S, Freile P, Ganeva VV, Wildenhain J, Bradley M, Pawson A, Millar R, De Sousa PA.
- Stem cell research.Stem Cell Res.2012 Nov;9(3):171-84. doi: 10.1016/j.scr.2012.06.007. Epub 2012 Jul 5.
- Multiple signalling pathways maintain human embryonic stem cells (hESC) in an undifferentiated state. Here we sought to define the significance of G protein signal transduction in the preservation of this state distinct from other cellular processes. Continuous treatment with drugs targeting G(αs)-
- PMID 22877821
Japanese Journal
- G.ALPHA.q-Protein Carboxyl Terminus Imitation Polypeptide GCIP-27 Attenuates Proliferation of Vascular Smooth Muscle Cells and Vascular Remodeling in Spontaneously Hypertensive Rats
- Zhang Hai-Gang,Cheng Yi-Qun,Liu Ya [他],Zhou Jian-Zhi,Jia Yi,Wang Xiu-Qin,Li Xiao-Hui
- Biological and Pharmaceutical Bulletin 34(10), 1527-1532, 2011
- … The carboxyl terminus of Gα-subunit plays a vital role in G-protein-receptor interaction. … The present study was designed to explore the effects of a synthetic Gαq carboxyl terminus imitation peptide, namely GCIP-27, on vascular smooth muscle cells (VSMC) in vitro and vascular remodeling in spontaneous hypertensive rats (SHR). …
- NAID 130001086583
- Diacylglycerol kinase zeta inhibits G alpha q-induced atrial remodeling in transgenic mice
- Hirose M,Takeishi Y,Niizeki T,Shimojo H,Nakada T,Kubota I,Nakayama J,Mende U,Yamada M
- HEART RHYTHM 6(1), 78-84, 2009-01
- NAID 120001356496
- The Rab GTPase-Activating Protein AS160 as a Common Regulator of Insulin- and G.ALPHA.q-Mediated Intracellular GLUT4 Vesicle Distribution
- YUASA Tomoyuki,UCHIYAMA Keiji,OGURA Yuko,KIMURA Masafumi,TESHIGAWARA Kiyoshi,HOSAKA Toshio,TANAKA Yoshinori,OBATA Toshiyuki,SANO Hiroyuki,KISHI Kazuhiro,EBINA Yousuke
- Endocrine Journal 56(3), 345-359, 2009
- … We and others, previously reported that the activation of Gαq protein-coupled receptors (GαqPCRs) also stimulated GLUT4 translocation and glucose uptake in several cell lines. … Here, we report that the activation of GαqPCRs also promoted phosphorylation of AS160 by the 5′-AMP activated protein kinase (AMPK). … This suppression did not affect the ratio of non-induced cell surface GLUT4 to Gαq-induced it. …
- NAID 130004443498
Related Links
- G-alpha(q) a guanine nucleotide-binding protein of the G12 class of G-alpha proteins. Agonist binding to Gq-coupled receptors may block Akt activation via the release of active G-alpha(q) subunits that inhibit phosphatidylinositol 3 ...
- ... ... See More, G alpha gust, G alpha i, G alpha i1, G alpha i2, G alpha i3, G alpha o, G alpha olf, G alpha q, G alpha q14, G alpha s, G alpha t, G alpha t1, G alpha t2, G alpha z, G beta, G beta L, G beta 1, G beta 2, G beta 3, ...
Related Pictures
★リンクテーブル★
| リンク元 | 「Gαq」「Gαqサブユニット」 |
| 関連記事 | 「G」「Q」「alpha」「qd」「Gd」 |
「Gαq」
- 英
- (n
「Gαqサブユニット」
- 英
- (n
- 関
- Gαq
「G」
「Q」
「alpha」
- 関
- alfa
「qd」
- quaue die = once daily
- 1日1回