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1. 乳癌予防のための選択的エストロゲン受容体調節因子およびアロマターゼ阻害剤 selective estrogen receptor modulators and aromatase inhibitors for breast cancer prevention
2. 転移性ホルモン受容体陽性乳癌に対する治療アプローチ：内分泌療法 treatment approach to metastatic hormone receptor positive breast cancer endocrine therapy
3. 男性生殖生理学 male reproductive physiology
4. アロマターゼ阻害剤による骨量減少の評価およびマネージメント evaluation and management of aromatase inhibitor induced bone loss
5. 女性の不妊症の治療の概要 overview of treatment of female infertility

English Journal

Molecular mechanism of endocrine system impairment by 17α-methyltestosterone in gynogenic Pengze crucian carp offspring.

Zheng Y1, Chen J2, Liu Y3, Gao J3, Yang Y4, Zhang Y3, Bing X2, Gao Z5, Liang H6, Wang Z7.
Ecotoxicology and environmental safety.Ecotoxicol Environ Saf.2016 Jun;128:143-52. doi: 10.1016/j.ecoenv.2015.11.034. Epub 2016 Mar 1.
The effects of synthetic androgen 17α-methyltestosterone (MT) on endocrine impairment were examined in crucian carp. Immature 7-month old mono-female Pengze crucian carp (Pcc) F2 offspring were exposed to 50 and 100μg/L of MT (week 2, 4, and 8). Gonadosomatic index, hepatosomatic index and intesti
PMID 26938152

Computational model of the fathead minnow hypothalamic-pituitary-gonadal axis: Incorporating protein synthesis in improving predictability of responses to endocrine active chemicals.

Breen M1, Villeneuve DL2, Ankley GT3, Bencic D4, Breen MS5, Watanabe KH6, Lloyd AL7, Conolly RB8.
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP.Comp Biochem Physiol C Toxicol Pharmacol.2016 May-Jun;183-184:36-45. doi: 10.1016/j.cbpc.2016.02.002. Epub 2016 Feb 12.
There is international concern about chemicals that alter endocrine system function in humans and/or wildlife and subsequently cause adverse effects. We previously developed a mechanistic computational model of the hypothalamic-pituitary-gonadal (HPG) axis in female fathead minnows exposed to a mode
PMID 26875912

Prenatal exposure to soy and selenium reduces prostate cancer risk factors in TRAMP mice more than exposure beginning at six weeks.

Nakken HL1, Lephart ED2, Hopkins TJ1, Shaw B1, Urie PM3, Christensen MJ1,4.
The Prostate.Prostate.2016 May;76(6):588-96. doi: 10.1002/pros.23150. Epub 2016 Jan 28.
BACKGROUND: Diets high in soy and selenium (Se) decrease prostate cancer risk factors in healthy rats. The purpose of this study was to determine whether treatment with high levels of soy and/or supplemental Se would decrease prostate cancer risk factors in the Transgenic Adenocarcinoma of Mouse Pro
PMID 26817824

Steroidogenic enzyme expression in estrogen production in the goat gastrointestinal (GI) tract and the effect of castration

An immortalized steroidogenic goat granulosa cell line as a model system to study the effect of the endoplasmic reticulum (ER)-stress response on steroidogenesis