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- 1. 細菌性膣炎 bacterial vaginosis
- 2. 抗原虫治療 antiprotozoal therapies
- 3. トリコモナス trichomoniasis
- 4. 二核アメーバ dientamoeba fragilis
- 5. シャーガス病：抗トリパノソーマ薬療法 chagas disease antitrypanosomal drug therapy
English Journal
- Discovery and molecular modeling of novel 1-indolyl acetate - 5-Nitroimidazole targeting tubulin polymerization as antiproliferative agents.
- Duan YT1, Sang YL1, Makawana JA1, Teraiya SB1, Yao YF1, Tang DJ1, Tao XX1, Zhu HL2.
- European journal of medicinal chemistry.Eur J Med Chem.2014 Oct 6;85:341-51. doi: 10.1016/j.ejmech.2014.07.082. Epub 2014 Jul 30.
- A series of 18 novel 1-indolyl acetate-5-nitroimidazole 3a-3r were designed, synthesized, and evaluated for their in vitro biological activities as potential tubulin polymerization inhibitors. Among these compounds, 3p displayed strong antitumor activity with IC50 of 2.00, 1.05, 0.87 μM against A
- PMID 25105922
- Effects of rifampin and ketoconazole on pharmacokinetics of morinidazole in healthy chinese subjects.
- Pang X1, Zhang Y1, Gao R1, Zhong K1, Zhong D1, Chen X2.
- Antimicrobial agents and chemotherapy.Antimicrob Agents Chemother.2014 Oct;58(10):5987-93. doi: 10.1128/AAC.03382-14. Epub 2014 Jul 28.
- Morinidazole, a 5-nitroimidazole antimicrobial drug, has been approved for the treatment of amoebiasis, trichomoniasis, and anaerobic bacterial infections in China. It was reported that drug-drug interaction happened after the coadministration of ornidazole, an analog of morinidazole, and rifampin o
- PMID 25070100
- Reactions in Nitroimidazole Triggered by Low-Energy (0-2 eV) Electrons: Methylation at N1-H Completely Blocks Reactivity.
- Tanzer K1, Feketeová L, Puschnigg B, Scheier P, Illenberger E, Denifl S.
- Angewandte Chemie (International ed. in English).Angew Chem Int Ed Engl.2014 Sep 15. doi: 10.1002/anie.201407452. [Epub ahead of print]
- Low-energy electrons (LEEs) at energies of less than 2 eV effectively decompose 4-nitroimidazole (4NI) by dissociative electron attachment (DEA). The reactions include simple bond cleavages but also complex reactions involving multiple bond cleavages and formation of new molecules. Both simple and c
- PMID 25224248
Japanese Journal
- Microwave-Assisted Direct H/D Exchange Reactions of Dimetridazole and Metronidazole in Alkaline D₂O
- Bulletin of the Chemical Society of Japan 84(12), 1368-1370, 2011-12-15
- NAID 10030216676
- Reevaluation of the Radiosensitizing Effects of Sanazole and Nimorazole In Vitro and In Vivo
- Journal of radiation research 46(4), 453-459, 2005-12-28
- NAID 130000053212
- A Convenient Synthesis of Highly Conjugated 5-Nitroimidazoles
- Heterocycles 57(9), 1689-1695, 2002-09-01
- NAID 40005677485
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| リンク元 | 「5-ニトロイミダゾール」 |
| 関連記事 | 「nitroimidazole」 |