in vivo gene therapy

• 生体内遺伝子治療、インビボ遺伝子治療

WordNet

1. holding office; "the in party"
2. to or toward the inside of; "come in"; "smash in the door" (同)inwards, inward
3. currently fashionable; "the in thing to do"; "large shoulder pads are in"
4. directed or bound inward; "took the in bus"; "the in basket"
5. (medicine) the act of caring for someone (as by medication or remedial training etc.); "the quarterback is undergoing treatment for a knee injury"; "he tried every treatment the doctors suggested"; "heat therapy gave the best relief"
6. (genetics) a segment of DNA that is involved in producing a polypeptide chain; it can include regions preceding and following the coding DNA as well as introns between the exons; it is considered a unit of heredity; "genes were formerly called factors" (同)cistron, factor
7. informal term for information; "give me the gen on your new line of computers"

PrepTutorEJDIC

1. 《具体的な場所,位置》 / …『の中に』(『で』) / …『において』,…で / 《intoの代りに移動を表す動詞と共に》…『の中へ』 / (乗り物)『に乗って』 / …『の状熊に』(『で』) / …『に従事して』,に属して / …『を身につけて』,に覆われて / 《『in』do『ing』の形で》…『するときに』,する際に(when) / 《時間》 / …『して』,…『が経過したあと』 / …『の間に』 / …『については』,…の点では / 《方法・手段・材料》…『で』 / 《人を目的語にして,性質・能力があることを示して》…の中に / …の目的で,のつもりで,として / 《比率割合》…のうちで,につき / 《過去分詞に伴って》…に[…されて] / 『中へ』(に) / 『在宅して』,帰って / (乗り物などが)『到着して』,(時期・季節が)来て / 出回って,流行して / 《俗》流行の,当世風の / 《話》特定の人々にのみ理解される
2. (病気の)治療,療法 / =psychotherapy
3. 遺伝子

UpToDate Contents

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• 1. 原発性免疫不全症に対する遺伝子治療 gene therapy for primary immunodeficiency
• 2. 肝細胞移植 hepatocyte transplantation
• 3. 表皮水疱症のマネージメントの概要 overview of the management of epidermolysis bullosa
• 4. JAK3欠損を伴う重度複合型免疫不全（SCID） severe combined immunodeficiency scid with jak3 deficiency
• 5. 血友病の治療 treatment of hemophilia

English Journal

• Targeted gene delivery to the synovial pannus in antigen-induced arthritis by ultrasound-targeted microbubble destruction in vivo.

• Xiang X1, Tang Y1, Leng Q1, Zhang L1, Qiu L2.
• Ultrasonics.Ultrasonics.2016 Feb;65:304-14. doi: 10.1016/j.ultras.2015.09.011. Epub 2015 Sep 26.
• The purpose of this study was to optimize an ultrasound-targeted microbubble destruction (UTMD) technique to improve the in vivo transfection efficiency of the gene encoding enhanced green fluorescent protein (EGFP) in the synovial pannus in an antigen-induced arthritis rabbit model. A mixture of mi
• PMID 26433434

• The Corynebacterium pseudotuberculosis genome contains two formamidopyrimidine-DNA glycosylase enzymes, only one of which recognizes and excises 8-oxoguanine lesion.

• Arantes LS1, Nova LG2, Resende BC3, Bitar M4, Coelho IE5, Miyoshi A6, Azevedo VA7, Lara Dos Santos L8, Machado CR9, de Oliveira Lopes D10.
• Gene.Gene.2016 Jan 10;575(2 Pt 1):233-43. doi: 10.1016/j.gene.2015.08.065. Epub 2015 Sep 2.
• The GO-system is a DNA repair mechanism that prevents and corrects oxidative DNA damage. Formamidopyrimidine-DNA glycosylase (FPG/MutM) participates in this system, avoiding the mutagenic effects of 8-oxoguanine lesion into DNA. Corynebacterium pseudotuberculosis, the etiological agent of caseous ly
• PMID 26341054

• Bubble-Assisted Ultrasound: Application in Immunotherapy and Vaccination.

• Escoffre JM1, Deckers R2, Bos C3, Moonen C2.
• Advances in experimental medicine and biology.Adv Exp Med Biol.2016;880:243-61. doi: 10.1007/978-3-319-22536-4_14.
• Bubble-assisted ultrasound is a versatile technology with great potential in immunotherapy and vaccination. This technology involves the exposure of immune cells (i.e., dendritic cells, lymphocytes) in-vitro or diseased tissues (i.e., brain, tumor) in-vivo to ultrasound treatment with gas bubbles. B
• PMID 26486342

Japanese Journal

• Long-term in vivo gene expression in mouse kidney using φC31 integrase and electroporation

• Otani Yuki,Kawakami Shigeru,Mukai Hidefumi,Fuchigami Yuki,Yamashita Fumiyoshi,Hashida Mitsuru
• Journal of Drug Targeting 23(5), 427-435, 2015-06-01
• … Background: Achieving long-term gene expression in kidney will be beneficial for gene therapy of renal and congenital diseases, genetic studies constructing animal disease models, and the functional analysis of disease-related genes. … Purpose: The purpose of this study was to develop an in vivo long-term gene expression system in murine kidney using φC31 integrase. …
• NAID 120005621902

• Effects of a Tricaprylin Emulsion on Anti-glomerular Basement Membrane Glomerulonephritis in Rats: In Vivo and in Silico Studies

• Liu Ning,Shi Junfeng,Xiao Ying,Yasue Misato,Takei Yoshinori,Sanefuji Hayato,Tsujimoto Gozoh,Hirasawa Akira
• Biological and Pharmaceutical Bulletin 38(8), 1175-1184, 2015
• … Glomerulonephritis (GN) is a set of pathological conditions that result in the destruction of glomeruli and loss of renal function, commonly leading to the development of end-stage renal disease. … Current pharmacotherapy is limited to immunosuppressive therapy. … In the present study, we found a novel antinephritic effect of a tricaprylin emulsion in the anti-glomerular basement membrane (anti-GBM) GN rat model. …
• NAID 130005090652

• Efficient Adenovirus Gene Transfer Methods in Human Colonic Caco-2 Epithelial Cells Using Capric Acid

• Koizumi Naoya,Yamagishi Yoshiaki,Hirai Takamasa,Fujii Makiko,Mizuguchi Hiroyuki,Watanabe Yoshiteru
• Biological and Pharmaceutical Bulletin 38(8), 1240-1244, 2015
• … Adenovirus (Ad) vectors are widely used in gene therapy and in vitro/in vivo gene transfer. … However, Ad-mediated gene transfer in epithelial cells shows low efficiency, because Ad fiber cannot bind to the primary receptor, the coxsackievirus and adenovirus receptor (CAR), present in tight junctions. …
• NAID 130005090650

Related Links

• In vivo gene therapy - YouTube

This gene therapy lecture explains the process of in vivo gene therapy and the use of in vivo gene therapy in treating diseases. For more information, log on to- http://shomusbiology.weebly.com/ Download ...

• What Is in Vivo Gene Therapy? (with pictures)

In vivo gene therapy is a process by which the genetic makeup of cells is altered to produce a therapeutic effect that prevents or treats diseases. Defective or missing hereditary material — DNA — in the nucleus of the ...

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★リンクテーブル★

リンク元	「インビボ遺伝子治療」「生体内遺伝子治療」
関連記事	「vi」「therapy」「in vivo」「In」

「インビボ遺伝子治療」

　　[★]

英

in vivo gene therapy

関

生体内遺伝子治療、エクスビボ遺伝子治療

「生体内遺伝子治療」

　　[★]

英

in vivo gene therapy

関

インビボ遺伝子治療

「vi」

　　[★]

• 初速度 initial velocity

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linux

検索

:/<文字列>　：　文字列 を検索する（順方向） 
:?<文字列>　：　文字列を検索する（逆方向） 
:n　　　　　：　順方向へ検索する  
:N　　　　　：　逆方向へ検索する

終了

:q　　　　　：　(何も変更していない場合)保存せずに終了
:q!　　　　　：　(何か変更した場合)保存せずに終了

「therapy」

　　[★]

• n.

• 治療、治療法、療法

関

care、cure、curing、practice、psychotherapy、regimen、remediation、remedy、therapeutic、treat、treatment、treatment protocol

　 　

「in vivo」

　　[★]

• 体内の、インビボの、生体内で

関

internal、intravital

「In」

　　[★] インジウム indium