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magnifier of the image of small objects; "the invention of the microscope led to the discovery of the cell"

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Botulinum Neurotoxin Type A is Internalized and Translocated from Small Synaptic Vesicles at the Neuromuscular Junction.

Colasante C, Rossetto O, Morbiato L, Pirazzini M, Molgó J, Montecucco C.SourceLaboratoire de Neurobiologie et Développement, Institut de Neurobiologie Alfred Fessard, CNRS-UPR 3294, 91198, Gif-sur-Yvette Cedex, France.
Molecular neurobiology.Mol Neurobiol.2013 Mar 8. [Epub ahead of print]
Botulinum neurotoxin type A (BoNT/A) is the most frequent cause of human botulism and, at the same time, is largely used in human therapy. Some evidence indicates that it enters inside nerve terminals via endocytosis of synaptic vesicles, though this has not been directly proven. The metalloprotease
PMID 23471747

Three-dimensional distribution of TrkA neurotrophin receptors in neurite varicosities of differentiated PC12 cells treated with NGF determined by immunoelectron tomography.

Nishida T, Yoshimura R, Endo Y.SourceResearch Center for Ultra-High Voltage Electron Microscopy, Osaka University, Mihogaoka, Ibaraki, Osaka, Japan. nishida@uhvem.osaka-u.ac.jp
Cell and tissue research.Cell Tissue Res.2013 Jan;351(1):1-13. doi: 10.1007/s00441-012-1499-0. Epub 2012 Oct 26.
Nerve growth factor (NGF) initiates the activation of TrkA tyrosine kinase receptors and numerous subsequent signaling cascades. However, the dynamics of the process including the translocation of TrkA is still unclear. In this study, the effect of NGF or membrane depolarization on the endocytic pro
PMID 23100034

Production of Rous sarcoma virus-like particles displaying human transmembrane protein in silkworm larvae and its application to ligand-receptor binding assay

Tsuji Yoshitaka,Deo Vipin Kumar,Kato Tatsuya,Park Enoch Y.
Journal of biotechnology 155(2), 185-192, 2011-09-10
… VLPs were purified on 10-60% (v/v) sucrose density gradient by ultracentrifugation and their structures confirmed under electron microscope. … When hPRR and RSV Gag577 were co-expressed in silkworm larvae, human prorenin receptor (hPRR) was displayed on the surface of RSV VLPs, which was detected by Western blotting and immunoelectron microscopy. …
NAID 120003256123

Ichinose Akitoyo/ Watanabe Kiwao/ Senba Masachika/ Ahmed Kamruddin/ Ariyoshi Koya/ Matsumoto Keizo
Acta Medica Nagasakiensia 56(1), 1-4, 2011-06
… pneumoniae) under immunoelectron microscopy because of the thick mucopeptide cell wall hampering proper fixation. … pneumoniae capsule by immunoelectron microscope. …
NAID 110008581601