immune response genes defects

出典: meddic

Ir genes defects
MHC, major histocompatibility complex


Ir genes defects
MHC, major histocompatibility complex

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英文文献

  • Lack of HLA predominance and HLA shared epitopes in biliary Atresia.
  • Mack CL, Anderson KM, Aubrey MT, Rosenthal P, Sokol RJ, Freed BM.SourceDepartments of Medicine and Immunology, Division of Allergy and Clinical Immunology, University of Colorado School of Medicine, 80045 Aurora, CO USA ; Department of Pediatrics, Division of Pediatric Gastroenterology, Digestive Health Institute, Children's Hospital Colorado, Hepatology and Nutrition, 13123 East 16th Ave. B290, 80045 Aurora, CO USA.
  • SpringerPlus.Springerplus.2013 Dec;2(1):42. Epub 2013 Feb 8.
  • Biliary atresia (BA) is characterized by progressive inflammation and fibrosis of bile ducts. A theory of pathogenesis entails autoimmune-mediated injury targeting bile duct epithelia. One of the strongest genetic associations with autoimmunity is with HLA genes. In addition, apparently dissimilar H
  • PMID 23505615
  • MTG16 contributes to colonic epithelial integrity in experimental colitis.
  • Williams CS, Bradley AM, Chaturvedi R, Singh K, Piazuelo MB, Chen X, McDonough EM, Schwartz DA, Brown CT, Allaman MM, Coburn LA, Horst SN, Beaulieu DB, Choksi YA, Washington MK, Williams AD, Fisher MA, Zinkel SS, Peek RM Jr, Wilson KT, Hiebert SW.SourceDepartment of Medicine, Division of Gastroenterology, Vanderbilt University, Nashville, Tennessee, USA.
  • Gut.Gut.2013 Oct;62(10):1446-55. doi: 10.1136/gutjnl-2011-301439. Epub 2012 Jul 24.
  • OBJECTIVE: The myeloid translocation genes (MTGs) are transcriptional corepressors with both Mtg8(-/-) and Mtgr1(-/-) mice showing developmental and/or differentiation defects in the intestine. We sought to determine the role of MTG16 in intestinal integrity.METHODS: Baseline and stress induced colo
  • PMID 22833394
  • Lowered expression levels of a tumor suppressor gene - Caveolin-1 within dysregulated gene networks of Fanconi anemia.
  • Shyamsunder P, Vidyasekar P, Shukla AR, Mohan S, Verma RS.SourceStem cell and Molecular Biology laboratory, Department of Biotechnology, Indian Institute of Technology Madras, Chennai 600 036, India.
  • Gene.Gene.2013 Sep 25;527(2):521-8. doi: 10.1016/j.gene.2013.06.051. Epub 2013 Jul 9.
  • Fanconi anemia (FA) is a genetic disorder characterized by progressive bone marrow failure and a predisposition to cancers like acute myeloid leukemia, lung and squamous cell carcinomas. DNA damage in a healthy cell activates the FA pathway where 15 individual FA proteins interact and function toget
  • PMID 23845778

関連リンク

im·mune re·sponse genes genes in the HLA-D region of the histocompatibility complex of human chromosome 6 that control the immune response to specific antigens. im·mune re·sponse genes (i-myūn' rĕ-spons' jēnz) Genes in the ...
However, the role of these genes in the immune response is only known for a few of them. To evaluate the role of these genes in antifungal immune responses, we examined the effect of individual mutations on the immune ...

関連画像

 immune response to mycobacterial immune response which leads to cell deathFigure 1. Requirements for the development  defects , IFN-gamma receptors can be defects including aberrant expression ofbe caused by an aberrant immune response


★リンクテーブル★
関連記事defect」「immune」「response」「gene」「gen

defect」

  [★]

  • n.
aberrantaberrantlyaberrationabnormalabnormalityabnormallyabsenceagenesisanomalousanomalouslyanomalydefectivedeficiencydeficientdeficitdeletiondeletionaldeviantdrawbackextraordinarilyextraordinaryfaultflawinadequacymissmissingmorphological defectshortcomingunusualunusuallyweakness

WordNet   license wordnet

「desert (a cause, a country or an army), often in order to join the opposing cause, country, or army; "If soldiers deserted Hitler''s army, they were shot"」
desert

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「an imperfection in an object or machine; "a flaw caused the crystal to shatter"; "if there are any defects you should send it back to the manufacturer"」
fault, flaw

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「an imperfection in a bodily system; "visual defects"; "this device permits detection of defects in the lungs"」

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「a failing or deficiency; "that interpretation is an unfortunate defect of our lack of information"」
shortcoming

PrepTutorEJDIC   license prepejdic

「〈C〉『欠点』,弱点,欠陥 / 〈U〉〈C〉《古》不足,欠乏 / (国・党・主義などから)離脱する,裏切って出る《+『from』+『名』》;離反して(…に)転向する《+『to』+『名』》」


immune」

  [★]

  • adj.
  • 免疫の、免疫性の
immunisationimmuniseimmunityimmunizationimmunizeimmunoimmunologic

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「secure against; "immune from taxation as long as he resided in Bermuda"; "immune from criminal prosecution"」

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「a person who is immune to a particular infection」

PrepTutorEJDIC   license prepejdic

「免疫の / 《補語にのみ用いて》(影響・攻撃・義務・税などを)免れている《+『against』(『from, to』)+『名』》」

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「relating to or conferring immunity (to disease or infection)」
resistant

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「(usually followed by `to'」

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「relating to the condition of immunity; "the immune system"」

response」

  [★]

  • n.

WordNet   license wordnet

「a result; "this situation developed in response to events in Africa"」

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「a phrase recited or sung by the congregation following a versicle by the priest or minister」

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「the manner in which an electrical or mechanical device responds to an input signal or a range of input signals」

PrepTutorEJDIC   license prepejdic

「〈C〉(…に対する)『返事』,『返答』《+『to』+『名』》 / 〈C〉〈U〉(…に対する)『反応』,『反響』《『to』+『名』》 / 〈C〉応答歌,応唱(牧師にならって合唱隊・会衆が短い祈り・歌を応答すること)」


gene」

  [★] 遺伝子

WordNet   license wordnet

「(genetics) a segment of DNA that is involved in producing a polypeptide chain; it can include regions preceding and following the coding DNA as well as introns between the exons; it is considered a unit of heredity; "genes were formerly called factors"」
cistron, factor

PrepTutorEJDIC   license prepejdic

「遺伝子」

gen」

  [★]

WordNet   license wordnet

「informal term for information; "give me the gen on your new line of computers"」




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