WordNet

unrefined in character; "low comedy"
an air mass of lower pressure; often brings precipitation; "a low moved in over night bringing sleet and snow" (同)depression
a low level or position or degree; "the stock market fell to a new low"
used of sounds and voices; low in pitch or frequency (同)low-pitched
very low in volume; "a low murmur"; "the low-toned murmur of the surf" (同)low-toned
in a low position; near the ground; "the branches hung low"
less than normal in degree or intensity or amount; "low prices"; "the reservoir is low"
literal meanings; being at or having a relatively small elevation or upward extension; "low ceilings"; "low clouds"; "low hills"; "the sun is low"; "low furniture"; "a low bow"
(statistics) a coefficient assigned to elements of a frequency distribution in order to represent their relative importance (同)weighting
sports equipment used in calisthenic exercises and weightlifting; it is not attached to anything and is raised and lowered by use of the hands and arms (同)free weight, exercising weight
an artifact that is heavy
the vertical force exerted by a mass as a result of gravity
the relative importance granted to something; "his opinion carries great weight"; "the progression implied an increasing weightiness of the items listed" (同)weightiness
an oppressive feeling of heavy force; "bowed down by the weight of responsibility"
have a certain weight
determine the weight of; "The butcher weighed the chicken" (同)librate
to be oppressive or burdensome; "weigh heavily on the mind", "Something pressed on his mind" (同)press
relating to simple or elementary organization; "proceed by more and more detailed analysis to the molecular facts of perception"--G.A. Miller
relating to or produced by or consisting of molecules; "molecular structure"; "molecular oxygen"; "molecular weight is the sum of all the atoms in a molecule"
adjusted to reflect value or proportion; "votes weighted according to the size of constituencies"; "a law weighted in favor of landlords"; "a weighted average"

PrepTutorEJDIC

(高さ・位置が)『低い』,低い所にある / (価格・数量・程度などが)『低い』,少ない / (身分・地位などが)『低い』,卑しい / (人格・行為などが)『卑しい』,下劣な,下品な / 《補語にのみ用いて》(体が)『弱った』;元気のない,憂うつな / (供給が)不十分な;(…が)乏しい《+『in』(『on』)+『名』》 / (音・声が)低い,小さい / (生物が)下等な / 『低く』,低い所に / (価格・程度などが)『安く』,低く / 低い声(調子)で;静かに / 最低点,最低水準
(牛の)モーという鳴き声 / (牛が)モーと鳴く
〈u〉『重さ』,重量,目方;体重;《a weight》(…の)重さ《+of+名》 / 〈u〉重さ(重力が物体に及ぼす力) / 〈u〉衡法(重量を示す体係) / 〈c〉重量単位 / 〈c〉(はかりの)おもり,分銅;(一般に)重いもの,おもし / 〈u〉重要性,価値 / 〈u〉《しばしば a weight》精神的な重荷,負担 / (…で)…‘に'重荷を負わせる;…‘を'圧迫する;苦しめる《+名+with+名》 / …‘を'重くする
…‘の'『重さを計る』 / 〈ある重さ〉‘を'『計量する』,計る / (…と比較して)…‘を'『検討する』,考慮する〈+名 against+名〉 / 『重さがある』,目方がかかる / (…にとって)『重要である』,(‥に)重要糸される〈+with+名〉
分子の,分子による
《補語にのみ用いて》(…に)有利な《+toward+名》

UpToDate Contents

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1. 意義未確定の単クローン性免疫グロブリン血症（MGUS）の診断 diagnosis of monoclonal gammopathy of undetermined significance
2. 成人における尿蛋白排泄量の評価および非ネフローゼ域蛋白尿のみの評価 assessment of urinary protein excretion and evaluation of isolated non nephrotic proteinuria in adults
3. 原発性巣状分節性糸球体硬化症の治療 treatment of primary focal segmental glomerulosclerosis
4. 特発性膜性腎症の治療 treatment of idiopathic membranous nephropathy
5. 遺伝性低リン血症性くる病と腫瘍誘発性骨軟化症 hereditary hypophosphatemic rickets and tumor induced osteomalacia

English Journal

Tubular reabsorption of high, middle and low molecular weight proteins according to the tubulo-interstitial damage marker N-acetyl-β-D-glucosaminidase in glomerulonephritis.

Bazzi C1, Rizza V, Olivieri G, Casellato D, D'Amico G.
Journal of nephrology.J Nephrol.2014 Sep 17. [Epub ahead of print]
BACKGROUND: Proteinuria, the hallmark of glomerular diseases, is an independent predictor of end-stage renal disease (ESRD) progression. Proteinuria is a mixture of proteins of different molecular weight (MW) dependent on alterations of glomerular filtration barrier (GFB) and reabsorption impairment
PMID 25227764

The HNF4A R76W mutation causes atypical dominant Fanconi syndrome in addition to a β cell phenotype.

Hamilton AJ1, Bingham C, McDonald TJ, Cook PR, Caswell RC, Weedon MN, Oram RA, Shields BM, Shepherd M, Inward CD, Hamilton-Shield JP, Kohlhase J, Ellard S, Hattersley AT.
Journal of medical genetics.J Med Genet.2014 Mar;51(3):165-9. doi: 10.1136/jmedgenet-2013-102066. Epub 2013 Nov 27.
BACKGROUND: Mutation specific effects in monogenic disorders are rare. We describe atypical Fanconi syndrome caused by a specific heterozygous mutation in HNF4A. Heterozygous HNF4A mutations cause a beta cell phenotype of neonatal hyperinsulinism with macrosomia and young onset diabetes. Autosomal d
PMID 24285859

Urinary low-molecular-weight protein excretion in pediatric idiopathic nephrotic syndrome.

Chehade H1, Parvex P, Poncet A, Werner D, Mosig D, Cachat F, Girardin E.
Pediatric nephrology (Berlin, Germany).Pediatr Nephrol.2013 Dec;28(12):2299-306. doi: 10.1007/s00467-013-2569-6. Epub 2013 Aug 15.
BACKGROUND: Minimal change disease (MCD) and focal segmental glomerulosclerosis (FSGS) are the most common causes of idiopathic nephrotic syndrome (INS). We have evaluated the reliability of urinary neutrophil-gelatinase-associated lipocalin (uNGAL), urinary alpha1-microglobulin (uα1M) and urinary
PMID 23949592

Japanese Journal

軽微蛋白尿と沈渣中の尿細管上皮を契機に発見された特発性尿細管性蛋白尿症の1女児例

鈴木康一,中畑徹,田中完,差波司,和賀忍,関根孝司,五十嵐隆,伊藤悦朗
日本小児科学会雑誌 106(11), 1672-1675, 2002-11-01
NAID 10010333779

1歳で腎石灰化をきたした先天性尿細管性蛋白尿症の男児例

松山健,清水マリ子,中條綾,五月女友美子,五十嵐隆,伊藤拓
日本小児科学会雑誌 106(8), 1034-1036, 2002-08-01
NAID 10009581996

特発性尿細管性蛋白尿症の一家系

田中里江子,百井亨
Nihon Shoni Jinzobyo Gakkai Zasshi 13(1), 43-47, 2000
　診断時3歳の男児を発端者とするDent病の一家系を経験した。患児は3歳児検尿で蛋白尿を指摘され初診。尿蛋白 (++)，セルロースアセテート膜電気泳動でαグロブリンが46.9%，SDS-PAGE法による分子量4万以下の蛋白が49.5%を占め，尿中BMGが37，602μg/lと著増していた。8歳時に患児と母の遺伝子検索を行いCLCN5遺伝子異常のホモ接合で母はヘテロ接合であった。診断後7年の経過で腎 …
NAID 130000078215