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1. 鉄のバランス調節 regulation of iron balance

English Journal

Suppressed hepcidin expression correlates with hypotransferrinemia in copper-deficient rat pups but not dams.

Broderius M1, Mostad E, Prohaska JR.
Genes & nutrition.Genes Nutr.2012 Jul;7(3):405-14. doi: 10.1007/s12263-012-0293-7. Epub 2012 Mar 29.
Copper deficiency leads to anemia but the mechanism is unknown. Copper deficiency also leads to hypoferremia, which may limit erythropoiesis. The hypoferremia may be due to limited function of multicopper oxidases (MCO) hephaestin in enterocytes or GPI-ceruloplasmin in macrophages of liver and splee
PMID 22457245

Plasma protein levels are markers of pulmonary vascular permeability and degree of lung injury in critically ill patients with or at risk for acute lung injury/acute respiratory distress syndrome.

Aman J1, van der Heijden M, van Lingen A, Girbes AR, van Nieuw Amerongen GP, van Hinsbergh VW, Groeneveld AB.
Critical care medicine.Crit Care Med.2011 Jan;39(1):89-97. doi: 10.1097/CCM.0b013e3181feb46a.
OBJECTIVES: To evaluate the diagnostic value of plasma protein levels for pulmonary vascular permeability and acute respiratory distress syndrome. During acute lung injury and acute respiratory distress syndrome, increased vascular permeability induces protein-rich fluid extravasation. We hypothesiz
PMID 21057316

Crosstalk between Iron Metabolism and Erythropoiesis.

Li H1, Ginzburg YZ.
Advances in hematology.Adv Hematol.2010;2010:605435. doi: 10.1155/2010/605435. Epub 2010 Jun 10.
Iron metabolism and erythropoiesis are inextricably linked. The majority of iron extracted from circulation daily is used for hemoglobin synthesis. In the last 15 years, major advances have been made in understanding the pathways regulating iron metabolism. Hepcidin is a key regulator of iron absorp
PMID 20631898

Japanese Journal

Molecular analysis of the transferrin gene in a patient with hereditary hypotransferrinemia

ASADA(SENJU) Midori,MAEDA Toyoki,SAKATA Toshiie,HAYASHI Akira,SUZUKI Tomokazu
Journal of human genetics 47(7), 355-359, 2002-07-01
NAID 50000573872

A Case of Atransferrinemia and 35 Cases of Hypotransferrinemia as Detected by Radioassay of Total Iron-binding Capacity of the Serum

Saito Hiroshi [他]
Japanese Journal of Medicine 16(4), p342-348, 1977-10
NAID 40005320277

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Hepatic Hemosiderosis Mri The first recorded case Atransferrinemia by Christer, Emory Download figure Open in new tab Download If you're the site owner , log in to The Ins and Outs of Iron Homeostasis fig2:Crosstalk between Iron Metabolism and