hypoparathyroidism

出典: meddic

副甲状腺機能低下症

WordNet   license wordnet

「inadequate secretion of parathyroid hormone resulting in abnormally low levels of calcium in the blood」

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2016/06/01 11:12:59」(JST)

wiki en

[Wiki en表示]

UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

英文文献

  • Necessity of therapy for post-thyroidectomy hypocalcaemia: a multi-centre experience.
  • De Pasquale L1, Sartori PV, Vicentini L, Beretta E, Boniardi M, Leopaldi E, Gini P, La Manna L, Cozzaglio L, Steffano GB, Andreani S, Badiali S, Cantoni GM, Galimberti A, Ghilardi G, Gusmeroli M, Maggiore R, Morenghi E, Pauna J, Poggi L, Testa V.
  • Langenbeck's archives of surgery / Deutsche Gesellschaft fur Chirurgie.Langenbecks Arch Surg.2015 Mar 8. [Epub ahead of print]
  • PURPOSE: Hypoparathyroidism is one of the most common and most feared complications of total thyroidectomy (TT). The aim of this study is to detect possible markers that may facilitate early tracing of hypocalcaemia-prone patients in order to reduce clinical cost by optimizing patient discharge and
  • PMID 25749741
  • The Epidemiology of Non-Surgical Hypoparathyroidism in Denmark: A Nationwide Case Finding Study.
  • Underbjerg L1, Sikjaer T, Mosekilde L, Rejnmark L.
  • Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.J Bone Miner Res.2015 Mar 7. doi: 10.1002/jbmr.2501. [Epub ahead of print]
  • Non-surgical hypoparathyroidism (HypoPT) is a rare disorder most often caused by mutations in different genes. It is characterized by hypocalcaemia with inappropriately low PTH levels. Knowledge on this group of patients, including their mortality and morbidity are very sparse. The aim was to identi
  • PMID 25753591
  • Shire bags NPS, including newly approved biologic for hypoparathyroidism.
  • [No authors listed]
  • Nature biotechnology.Nat Biotechnol.2015 Mar 6;33(3):226. doi: 10.1038/nbt0315-226c.
  • PMID 25748904

和文文献

  • Predictive factors for intraoperative excessive bleeding in Graves' disease
  • Yamanouchi Kosho,Minami Shigeki,Hayashida Naomi,Sakimura Chika,Kuroki Tamotsu,Eguchi Susumu
  • Asian Journal of Surgery 38(1), 1-5, 2015-01
  • … Occurrences of postoperative complications, such as recurrent laryngeal nerve palsy or hypoparathyroidism, and postoperative hospital stay were not correlated with AIOBL. …
  • NAID 120005606104
  • Bone mineral density in treated at a young age for differentiated thyroid cancer after Chernobyl female patients on TSH-suppressive therapy receiving or not Calcium-D3 supplementation
  • , , , , , , , ,
  • Endocrine Journal 62(2), 173-182, 2015
  • … Long-term management of patients with differentiated thyroid cancer (DTC) commonly includes TSH-suppressive therapy with L-T4 and, in case of postsurgical hypoparathyroidism, Calcium-D3 supplementation, both of which may affect skeletal health. …
  • NAID 130004770483
  • 甲状腺手術時の副甲状腺の取り扱いについて (特集 先達の背中から見た甲状腺・副甲状腺外科の明日)
  • 菊地 勝一,松塚 文夫,岸本 昌浩
  • 日本内分泌・甲状腺外科学会雑誌 = Official journal of the Japan Association of Endocrine Surgeons and the Japanese Society of Thyroid Surgery 31(1), 19-23, 2014-03
  • NAID 40020103216

関連リンク

Hypoparathyroidism Answers provides information about the symptoms, diagnosis and management of hypoparathyroidism for patients and healthcare professionals. ... Nancy discusses the role of calcium in her life. Watch Nancy’s ...
The Hypoparathyroidism Association is directed by volunteers affected by hypoparathyroidism and overseen by a Medical Advisory Board. It is devoted to all forms of hypoparathyroidism, a rare medical disorder in which the ...

関連画像

Hypoparathyroidism symptoms diagrampara: HypoparathyroidismHypoparathyroidismHyperparathyroidismPictures Of Hypoparathyroidismhypoparathyroidism mechanism of disease


★リンクテーブル★
リンク元副甲状腺機能低下症」「上皮小体低下症
拡張検索idiopathic hypoparathyroidism」「pseudopseudohypoparathyroidism」「pseudohypoparathyroidism

副甲状腺機能低下症」

  [★]

hypoparathyroidism
上皮小体機能低下症
上皮小体

病態

→腎:(1)リン酸再吸収↑、(2)カルシウム再吸収↓、(3)HCO3-排泄↓、(4)活性ビタミンD3↓ →
→骨:破骨細胞機能低下 → (1)カルシウム放出↓、(2)リン酸放出↓ →
→ 低カルシウム血症

症状

  • 中枢神経:不穏、易興奮性、うつ状態、知能発育遅延
  • 骨格筋:テタニー、強直性痙攣

身体所見

IMD
  • 低カルシウム血症:
  • Chvostek徴候:耳下腺前の頬部をハンマーで叩くと顔面神経を刺激して口輪筋の攣縮が起こる現象
  • Trousseau徴候:マンシェットを締め前腕を阻血化すると、強直性痙攣が起こり助産婦手位を示す現象

検査

  • 血液検査:
  • 血清カリウム低値、血清リン高値、尿中カルシウム低下、尿中リン低下
  • intact PTH:特発性副甲状腺機能低下症では、偽性副甲状腺機能低下症では高値。
  • 血清マグネシウム:正常 ← マグネシウム欠乏によりPTH分泌障害と作用不全を呈する(YN.D-50)
  • 心電図上:QT延長


上皮小体低下症」

  [★]

hypoparathyroidism
副甲状腺機能低下症特発性副甲状腺機能低下症


idiopathic hypoparathyroidism」

  [★]

特発性副甲状腺機能低下症

hypoparathyroidism


pseudopseudohypoparathyroidism」

  [★] 偽性偽性副甲状腺機能低下症


pseudohypoparathyroidism」

  [★] 偽性副甲状腺機能低下症




★コメント★

[メモ入力エリア]
※コメント5000文字まで
ニックネーム:
コメント:




表示
個人用ツール


  meddic.jp

リンク
連絡