hypoadiponectinemia

低アディ・ネクチン血症

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Lau WB, Tao L, Wang Y, Li R, Ma XL.Source1 Department of Emergency Medicine, Thomas Jefferson University , Philadelphia, Pennsylvania.
Antioxidants & redox signaling.Antioxid Redox Signal.2011 Oct 1;15(7):1863-73. Epub 2011 Apr 20.
Abstract Adiponectin (Ad) is an abundant protein hormone regulatory of numerous metabolic processes. The 30?kDa protein originates from adipose tissue, with full-length and globular domain circulatory forms. A collagenous domain within Ad leads to spontaneous self-assemblage into various oligomeri
PMID 21091079

Hypoadiponectinemia in Type 2 Diabetes: Molecular Mechanisms and Clinical Significance.

Su H, Lau WB, Ma XL.SourceDepartment of Geriatrics, Xijing Hospital, Xi-an, China and Department of Emergency Medicine, Thomas Jefferson University, Philadelphia, USA.
Clinical and experimental pharmacology & physiology.Clin Exp Pharmacol Physiol.2011 Sep 14. doi: 10.1111/j.1440-1681.2011.05606.x. [Epub ahead of print]
1.?This review focuses upon the regulatory mechanisms of adiponectin (APN) gene expression during physiologic conditions, and both the clinical significance and underlying molecular mechanisms of hypoadiponectinemia during pathologic conditions. 2.?APN is a versatile cardiovascular protective fa
PMID 21916932

Association between Metabolic Syndrome and Carotid Atherosclerosis: Relevance of Combined Criteria Including the Serum Adiponectin Level for the General Population

Abiko Akihiko,Makita Shinji,Naganuma Yujirou,Nagai Mizuyoshi,Nakamura Motoyuki
Internal Medicine 50(5), 381-387, 2011
… When the waist circumference was replaced by hypoadiponectinemia in the current MetS criteria, the odds ratio was significantly increased in men (OR=1.82, p=0.032). … Incorporating hypoadiponectinemia into the current criteria would be useful for the early detection of atherosclerosis in men. …
NAID 130000649847

Establishment of a concept of visceral fat syndrome and discovery of adiponectin

MATSUZAWA Yuji
Proceedings of the Japan Academy, Series B 86(2), 131-141, 2010
… Therefore hypoadiponectinemia induced by visceral fat accumulation should become a strong risk factor for metabolic and cardiovascular diseases and also some kinds of cancers.In this review article, I would like to discuss the mechanism of life style-related diseases by focusing on the dysregulation of adiponectin related to obesity, especially visceral obesity.(Communicated by Hiroo IMURA, M.J.A.) …
NAID 130000168769