hypereosinophilic syndrome

出典: meddic

好酸球増多症候群 HES


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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2014/10/14 06:42:10」(JST)

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英文文献

  • Eosinophilic cystitis in a patient with hypereosinophila syndrome: A case report.
  • Jiang P, Wang C, Jin B, Lin Y, Chen S.
  • Experimental and therapeutic medicine.Exp Ther Med.2014 Jul;8(1):49-51. Epub 2014 May 12.
  • Hypereosinophilic syndrome (HES) is a rare disorder that is characterized by hypereosinophilia and organ damage, caused by the infiltration of eosinophils. In rare cases, the urinary bladder may also be involved. The current case report presented a 56-year-old male with gross hematuria and hypereosi
  • PMID 24944595
  • Löffler endocarditis with multiple cerebral embolism.
  • Wang S1, Wang A1, Guo B1, Zhu S1, Chi Z1, Zhao X2.
  • Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association.J Stroke Cerebrovasc Dis.2014 Jul;23(6):1709-12. doi: 10.1016/j.jstrokecerebrovasdis.2013.10.023. Epub 2014 Feb 13.
  • Idiopathic hypereosinophilic syndrome is an uncommon leukoproliferative systemic disorder characterized by the sustained eosinophilia and target organ damage. We report the case of a 56-year-old man presenting with multiple cerebral embolism, Löffler endocarditis, and hypereosinophilia. This patien
  • PMID 24529355
  • Hypereosinophilic syndrome.
  • Hsieh FH.
  • Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.Ann Allergy Asthma Immunol.2014 Jun;112(6):484-8. doi: 10.1016/j.anai.2014.03.004. Epub 2014 Apr 13.
  • OBJECTIVE: To summarize the identified molecular and cellular mechanisms relevant to clinicians evaluating patients with hypereosinophilic syndrome (HES).DATA SOURCES: Review of relevant peer-reviewed literature.STUDY SELECTIONS: Studies on the pathogenesis of HES in relation to consensus definition
  • PMID 24726650

和文文献

  • 専門医のためのアレルギー学講座 9.好酸球増多を主徴とする疾患(1)Idiopathic Hypereosinophilic Syndrome (idiopathic HES)
  • 松尾 佳美,猪熊 茂子
  • アレルギー 60(1), 1-8, 2011-01-30
  • NAID 110008440530
  • IL-5の著明な高値を認めた特発性好酸球増多症の1例
  • 坂本 謙一,今村 俊彦,塩見 梢 [他]
  • 日本小児科学会雑誌 115(1), 97-101, 2011-01
  • NAID 40018699544

関連リンク

Hypereosinophilic syndrome (HES) is a myeloproliferative disorder (MPD) characterized by persistent eosinophilia that is associated with damage to multiple organs. [1, 2, 3, 4, 5, 6] Peripheral eosinophilia with tissue damage has been noted for approximately 80 years, but Hardy and Anderson first ...
特発性好酸球増加症(hypereosinophilic syndrome、HES )は1968年に疾患概念が提 唱され(Ref)、その診断基準は1975年に作成されました(Ref)(表2)。その内容は除外 診断であり、多くの病態が包括される不均一な症候群と ...
Epidemiology Frequency United States Various sources indicate that the prevalence of true hypereosinophilic syndrome is rare. The most common cause of eosinophilia in the United States is an allergic reaction or allergic disease ...

関連画像

Hypereosinophilic syndromeHypereosinophilic Syndrome is one of the HYPEREOSINOPHILIC SYNDROME Eosinophilic Idiopathic Hypereosinophilic Syndrome with  hypereosinophilic syndrome and in Hypereosinophilic Syndrome Image


★リンクテーブル★
リンク元イマチニブ」「好酸球増多症候群」「好酸球増加症候群」「Loeffler's endocarditis」「HES
拡張検索chronic eosinophilic leukemia/hypereosinophilic syndrome
関連記事syndrome

イマチニブ」

  [★]

imatinib
imatinib mesylate
グリベック
nib
分子標的薬剤

分類

  • その他
  • チロシンキナーゼ阻害薬

特徴

構造

作用機序

  • ABLや、活性複合体であるv-ABL, BCR-ABL, [EVT6]-ABLを阻害する (GOO.1367)
  • (そのほかに)PDGFRとKITに対しても競合阻害作用を持つ (GOO.1367)
KITはgastrointestinal stromal tumor(GIST)と関連
ETV6-PDGFRはchronic myelomonocytic leukemia(CMML)と関連
FIP1L1-PDGFRAはhypereosinophilic syndrome(HES)と関連

薬理作用

動態

  • 経口投与

適応

グリベック錠100mg

  • 1. 慢性骨髄性白血病
  • 2. KIT陽性消化管間質腫瘍
  • 3. フィラデルフィア染色体陽性急性リンパ性白血病

注意

禁忌

副作用

相互作用

類似薬

添付文書

  • グリベック錠100mg
[display]http://www.info.pmda.go.jp/go/pack/4291011F1028_1_11/4291011F1028_1_11?view=body




好酸球増多症候群」

  [★]

hypereosinophilic syndrome, HES
hypereosinophilic syndrome
  • hypereosinophilic syndrome
好酸球増加症候群特発性好酸球増多症候群好酸球性白血病レフラー心内膜炎


好酸球増加症候群」

  [★]

hypereosinophilic syndrome
好酸球増多症候群
-播種性好酸球性膠原病
HES
-HES
hypereosinophilic syndrome
HES
-好酸球性白血病


Loeffler's endocarditis」

  [★]

レフラー心内膜炎Loeffler心内膜炎

eosinophilic leukemiahypereosinophilic syndromeidiopathic hypereosinophilic syndrome


HES」

  [★]


chronic eosinophilic leukemia/hypereosinophilic syndrome」

  [★] 慢性好酸球性白血病/好酸球増加症候群


syndrome」

  [★]

  • n.

WordNet   license wordnet

「a pattern of symptoms indicative of some disease」

WordNet   license wordnet

「a complex of concurrent things; "every word has a syndrome of meanings"」

PrepTutorEJDIC   license prepejdic

「(疾患の徴候となる一群の)症徴候,症候群 / (事件・社会的状態などのパターンを示す)徴候形態」




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