疎水性蛋白質
WordNet
- any of a large group of nitrogenous organic compounds that are essential constituents of living cells; consist of polymers of amino acids; essential in the diet of animals for growth and for repair of tissues; can be obtained from meat and eggs and milk and legumes; "a diet high in protein"
- lacking affinity for water; tending to repel and not absorb water; tending not to dissolve in or mix with or be wetted by water
- abnormally afraid of water (同)aquaphobic
PrepTutorEJDIC
- 蛋白(たんばく)質
UpToDate Contents
全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.
English Journal
- Rational screening of peroxisome proliferator-activated receptor-γ agonists from natural products: potential therapeutics for heart failure.
- Chen R1, Wan J1, Song J1, Qian Y1, Liu Y1, Gu S2.
- Pharmaceutical biology.Pharm Biol.2017 Dec;55(1):503-509.
- PMID 27937122
- Determining equilibrium partition coefficients between lipid/protein and polydimethylsiloxane for highly hydrophobic organic contaminants using preloaded disks.
- Pei Y1, Li H2, You J3.
- The Science of the total environment.Sci Total Environ.2017 Nov 15;598:385-392. doi: 10.1016/j.scitotenv.2017.04.123. Epub 2017 Apr 24.
- PMID 28448930
- Anhydrous reverse micelle nanoparticles: new strategy to overcome sedimentation instability of peptide-containing pressurized metered-dose inhalers.
- Huang Z1, Wu H1, Yang B2, Chen L1, Huang Y1, Quan G1, Zhu C1, Li X1, Pan X1, Wu C1.
- Drug delivery.Drug Deliv.2017 Nov;24(1):527-538. doi: 10.1080/10717544.2016.1269850.
- PMID 28181839
Japanese Journal
- Effect of Ca²⁺ on the activity and structure of α-glucosidase : Inhibition kinetics and molecular dynamics simulations
- Zhang Xin,Shi Long,Li Xuan [他],Sheng Qing,Yao Ling,Shen Dong,Lu Zhi-Rong,Zhou Hai-Meng,Park Yong-Doo,Lee Jinhyuk,Zhang Qian
- Journal of bioscience and bioengineering 117(6), 696-705, 2014-06
- … inhibited α-glucosidase in a mixed-type reaction (K_i=27.0 ± 2.0 mM) and directly induced the unfolding of α-glucosidase, which resulted in the exposure of hydrophobic residues. …
- NAID 110009823153
- Protein Cytoplasmic Delivery using Polyampholyte Nanoparticles and Freeze Concentration
- Ahmed Sana,Hayashi Fumiaki,Nagashima Toshio,Matsumura Kazuaki
- Biomaterials 35(24), 6508-6518, 2014-05-10
- … A protein delivery method using freeze concentration was presented with a variety of polyampholyte nanocarriers. … In order to develop protein nanocarriers, hydrophobically modified polyampholytes were synthesized by the succinylation of ε-poly-L-lysine with dodecyl succinic anhydride and succinic anhydride. … The self-assembled polyampholyte aggregated form nanoparticles through intermolecular hydrophobic and electrostatic interactions when dissolved in aqueous media. …
- NAID 120005473123
- Involvement of Val 315 located in the C-terminal region of thermolysin in its expression in Escherichia coli and its thermal stability.
- Kojima Kenji,Nakata Hiroki,Inouye Kuniyo
- Biochimica et biophysica acta -Proteins and Proteomics 1844(2), 330-338, 2014-02
- … The variants substituted with hydrophobic amino acids such as Leu and Ile were almost the same as wild-type thermolysin (WT) in the expression amount, α-helix content, and stability. … All variants exhibited considerably high activities (50-100% of WT) in hydrolyzing protein and peptide substrates. … Crystallographic study of thermolysin has indicated that V315 is a member of the C-terminal hydrophobic cluster. …
- NAID 120005359199
Related Links
- Recent proteomic studies have led scientists to estimate that there are almost a million different proteins in a single human cell. The function and properties of these proteins are highly distinct ranging from structural proteins involved ...
- Hydrophilic and hydrophobic amino acids Depending on the polarity of the side chain, amino acids vary in their hydrophilic or hydrophobic character. These properties are important in protein structure and protein-protein interactions.
★リンクテーブル★
[★]
- 関
- hydrophobically、hydrophobicity、lyophobic