- ・酸ヒドロコルチゾン
- 関
- hydrocortisone、hydrocortisone aceponate、hydrocortisone buteprate、hydrocortisone butyrate、hydrocortisone butyrate propionate、hydrocortisone cypionate、hydrocortisone sodium phosphate、hydrocortisone sodium succinate、hydrocortisone succinate
WordNet
- a salt or ester of acetic acid (同)ethanoate
- an adrenal-cortex hormone (trade names Hydrocortone or Cortef) that is active in carbohydrate and protein metabolism (同)cortisol, Hydrocortone, Cortef
PrepTutorEJDIC
- 酢酸(さくさん)塩;アセテート(酢酸人造絹糸)
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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2017/01/21 21:24:19」(JST)
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- 1. 成人における単一恐怖に対する薬物療法 pharmacotherapy for specific phobia in adults
- 2. ACTHおよびコルチゾール分泌の生理学 physiology of acth and cortisol secretion
- 3. 胸腺神経内分泌（カルチノイド）腫瘍 thymic neuroendocrine carcinoid tumors
- 4. 血清および唾液中のコルチゾールの測定 measurement of cortisol in serum and saliva
- 5. 敗血症性ショックのステロイド療法 corticosteroid therapy in septic shock
English Journal
- Growth and reproductive development of male piglets are more vulnerable to mid-gestation maternal stress than that of female piglets.
- Mack LA1, Lay DC Jr, Eicher SD, Johnson AK, Richert BT, Pajor EA.Author information 1Department of Animal Sciences, Purdue University, West Lafayette, IN 47907.AbstractIn many mammalian species, prenatal stress masculinizes female and feminizes male offspring impairing their reproductive capacity. Regrouping gestating sows is a common, stressful production practice, but its impact on the sow's developing pigs is not fully known. This study examined the effects of regrouping gestating sows and the administration of exogenous glucocorticoids on the growth and external reproductive morphology of pigs. At 37.2 ± 0.26 d of gestation, 6 cohorts of 18 sows (N = 108) were placed in 1 of 3 treatments: socially stable (Stable), hydrocortisone acetate (HCA), or mixed (Mixed). The HCA sows were administered 70 mg HCA, a synthetic glucocorticoid, twice daily during the 21 d experimental period. Each Mixed sow was penned with 2 companion sows (Companion) and regrouped on d 7 and 14 with 2 different Companion sows in a new pen. Stable and HCA sows were penned in treatment groups of 3 sows. Sow social rank was assessed weekly during feeding. After the 21 d experimental period, all sows were housed in gestation stalls for the duration of pregnancy. During the 21 d, Companion sows gained more weight than HCA and Mixed sows (P < 0.05) with Stable sows intermediate. High ranked sows gained more weight than middle and low ranked sows (P < 0.05). Mixed sows had greater head lesion scores than Stable and HCA sows (P < 0.05) with Companion sows intermediate. Head lesions increased with lower social rank (P < 0.001). Sow treatment did not affect farrowing rate, litter size, or sex ratio (P > 0.10). Social rank also had no effect on farrowing rate (P > 0.10), but affected total litter size (P = 0.03). High ranked sows bore and weaned more live females than low ranked sows (P < 0.05), in part due to differential preweaning mortality among female pigs (P = 0.01). Only male pigs were affected by sow treatment. Preweaning mortality was higher among male pigs from HCA than from Mixed sows (P = 0.04) with other treatments intermediate. Despite no weight differences in the preweaning period, at 160 d of age males from HCA sows weighed more than males from Stable sows (P = 0.01) with other treatments intermediate. Males born to Companion sows had longer relative anogenital distances, a marker of fetal testosterone exposure, than males from Mixed sows (P = 0.03) with other treatments intermediate. The prenatal environment affected the pigs in a sex-specific manner altering the growth and reproductive morphology of the males more than that of the females.
- Journal of animal science.J Anim Sci.2014 Jan 7. [Epub ahead of print]
- In many mammalian species, prenatal stress masculinizes female and feminizes male offspring impairing their reproductive capacity. Regrouping gestating sows is a common, stressful production practice, but its impact on the sow's developing pigs is not fully known. This study examined the effects of
- PMID 24398844
- Degradation of corticosteroids during activated sludge processing.
- Miyamoto A1, Kitaichi Y, Uchikura K.Author information 1School of Pharmacy, Nihon University.AbstractLaboratory tests of the decomposition of corticosteroids during activated sludge processing were investigated. Corticosteroid standards were added to activated sludge, and aliquots were regularly taken for analysis. The corticosteroids were extracted from the samples using a solid-phase extraction method and analyzed LC-MS. Ten types of corticosteroids were measured and roughly classified into three groups: 1) prednisolone, triamcinolone, betamethasone, prednisolone acetate, and hydrocortisone acetate, which decomposed within 4 h; 2) flunisolide, betamethasone valerate, and budesonide of which more than 50% remained after 4 h, but almost all of which decomposed within 24 h; and 3) triamcinolone acetonide, and fluocinolone acetonide of which more than 50% remained after 24 h. The decomposed ratio was correlated with each corticosteroid's Log P, especially groups 2) and 3).
- Chemical & pharmaceutical bulletin.Chem Pharm Bull (Tokyo).2014;62(1):72-6.
- Laboratory tests of the decomposition of corticosteroids during activated sludge processing were investigated. Corticosteroid standards were added to activated sludge, and aliquots were regularly taken for analysis. The corticosteroids were extracted from the samples using a solid-phase extraction m
- PMID 24390495
- Validation of a thin-layer chromatography for the determination of hydrocortisone acetate and lidocaine in a pharmaceutical preparation.
- Dołowy M, Kulpińska-Kucia K, Pyka A.Author information Department of Analytical Chemistry, Faculty of Pharmacy, Medical University of Silesia, PL-4 Jagiellońska Street, 41-200 Sosnowiec, Poland.AbstractA new specific, precise, accurate, and robust TLC-densitometry has been developed for the simultaneous determination of hydrocortisone acetate and lidocaine hydrochloride in combined pharmaceutical formulation. The chromatographic analysis was carried out using a mobile phase consisting of chloroform + acetone + ammonia (25%) in volume composition 8 : 2 : 0.1 and silica gel 60F254 plates. Densitometric detection was performed in UV at wavelengths 200 nm and 250 nm, respectively, for lidocaine hydrochloride and hydrocortisone acetate. The validation of the proposed method was performed in terms of specificity, linearity, limit of detection (LOD), limit of quantification (LOQ), precision, accuracy, and robustness. The applied TLC procedure is linear in hydrocortisone acetate concentration range of 3.75 ÷ 12.50 μ g·spot(-1), and from 1.00 ÷ 2.50 μ g·spot(-1) for lidocaine hydrochloride. The developed method was found to be accurate (the value of the coefficient of variation CV [%] is less than 3%), precise (CV [%] is less than 2%), specific, and robust. LOQ of hydrocortisone acetate is 0.198 μ g·spot(-1) and LOD is 0.066 μ g·spot(-1). LOQ and LOD values for lidocaine hydrochloride are 0.270 and 0.090 μ g·spot(-1), respectively. The assay value of both bioactive substances is consistent with the limits recommended by Pharmacopoeia.
- TheScientificWorldJournal.ScientificWorldJournal.2014 Jan 6;2014:107879. doi: 10.1155/2014/107879. eCollection 2014.
- A new specific, precise, accurate, and robust TLC-densitometry has been developed for the simultaneous determination of hydrocortisone acetate and lidocaine hydrochloride in combined pharmaceutical formulation. The chromatographic analysis was carried out using a mobile phase consisting of chlorofor
- PMID 24526880
Japanese Journal
- Degradation of Corticosteroids during Activated Sludge Processing
- Chemical and Pharmaceutical Bulletin 62(1), 72-76, 2014
- NAID 130003381810
- Determination of Selected Corticosteroids in Sewage-treatment-plant Samples by Liquid Chromatography-mass Spectrometry
- Journal of Health Science 56(5), 547-556, 2010
- NAID 130000425090
- 吉草酸酢酸プレドニゾロンによる接触皮膚炎の１例
- 皮膚の科学 4(2), 111-115, 2005
- NAID 130004547109
Related Links
- A drug which inhibits or suppresses most inflammatory responses of an allergic, bacterial, traumatic or anaphylactic origin, as well as being immunosuppressant. They include the corticosteroids (e.g. betamethasone, dexamethasone, ...
- Find patient medical information for hydrocortisone acetate Rect on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings.
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★リンクテーブル★
| リンク元 | 「hydrocortisone buteprate」「hydrocortisone sodium phosphate」「hydrocortisone succinate」「hydrocortisone aceponate」「hydrocortisone cypionate」 |
| 関連記事 | 「hydrocortisone」 |
「hydrocortisone buteprate」
- 関
- cortisol、hydrocortisone、hydrocortisone aceponate、hydrocortisone acetate、hydrocortisone butyrate、hydrocortisone butyrate propionate、hydrocortisone cypionate、hydrocortisone sodium phosphate、hydrocortisone sodium succinate、hydrocortisone succinate
「hydrocortisone sodium phosphate」
- 関
- cortisol、hydrocortisone、hydrocortisone aceponate、hydrocortisone acetate、hydrocortisone buteprate、hydrocortisone butyrate、hydrocortisone butyrate propionate、hydrocortisone cypionate、hydrocortisone sodium succinate、hydrocortisone succinate
「hydrocortisone succinate」
- 関
- cortisol、hydrocortisone、hydrocortisone aceponate、hydrocortisone acetate、hydrocortisone buteprate、hydrocortisone butyrate、hydrocortisone butyrate propionate、hydrocortisone cypionate、hydrocortisone sodium phosphate、hydrocortisone sodium succinate
「hydrocortisone aceponate」
ヒドロコルチゾンアセ・ネート
- 関
- hydrocortisone、hydrocortisone acetate、hydrocortisone buteprate、hydrocortisone butyrate、hydrocortisone butyrate propionate、hydrocortisone cypionate、hydrocortisone sodium phosphate、hydrocortisone sodium succinate、hydrocortisone succinate
「hydrocortisone cypionate」
- 関
- hydrocortisone、hydrocortisone aceponate、hydrocortisone acetate、hydrocortisone buteprate、hydrocortisone butyrate、hydrocortisone butyrate propionate、hydrocortisone sodium phosphate、hydrocortisone sodium succinate、hydrocortisone succinate