human metapneumovirus infections

ヒトメタニューモウイルス感染症

WordNet

1. (medicine) the invasion of the body by pathogenic microorganisms and their multiplication which can lead to tissue damage and disease
2. (phonetics) the alteration of a speech sound under the influence of a neighboring sound
3. the pathological state resulting from the invasion of the body by pathogenic microorganisms
4. (international law) illegality that taints or contaminates a ship or cargo rendering it liable to seizure
5. moral corruption or contamination; "ambitious men are led astray by an infection that is almost unavoidable"
6. an incident in which an infectious disease is transmitted (同)contagion, transmission
7. sing with closed lips; "She hummed a melody"
8. a humming noise; "the hum of distant traffic" (同)humming
9. be noisy with activity; "This office is buzzing with activity" (同)buzz, seethe
10. sound with a monotonous hum (同)thrum
11. make a low continuous sound; "The refrigerator is humming"
12. relating to a person; "the experiment was conducted on 6 monkeys and 2 human subjects"
13. characteristic of humanity; "human nature"
14. having human form or attributes as opposed to those of animals or divine beings; "human beings"; "the human body"; "human kindness"; "human frailty"

PrepTutorEJDIC

1. 〈U〉(病気の)伝染;感染 / 〈C〉伝染病
2. 〈ハチ・機械などが〉『ブンブンいう』,ブーンと鳴る / 『鼻歌を歌う』,ハミングスル / (ちゅうちょ・当惑で)ふむふむいう / 《話》〈雰囲気・事業などが〉活気がある,活発に動く;(…で)活気づく《+『with』+『名』》 / …‘を'『ハミングで歌う』,鼻歌を歌って…‘を'(ある状熊に)する / (ハチ・機械などの)『ブンブン』[『うなる音』];鼻歌 / (雑踏などの)ガヤガヤ]いう音],騒音 / ふ‐む,う‐ん(ちゅうちょ・当惑・黙考・疑惑・不快などの声)
3. (動物・神に対して)『人間の』,人の / 『人間らいし』,人間的な,人情味のある / 〈C〉《複数形》(動物に怠して)人間(human being) / 〈U〉《the human》人類

UpToDate Contents

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• 1. ヒトメタニューモウイルス感染human metapneumovirus infections [show details]
  … new virus associated with respiratory disease in children and designated it human metapneumovirus (hMPV) . Data suggest that hMPV has been responsible for respiratory tract infections for at least 60 years …
• 2. 成人における市中肺炎の疫学、病因、および微生物学epidemiology pathogenesis and microbiology of community acquired pneumonia in adults [show details]
  …that have been detected in patients with CAP include rhinoviruses, coronaviruses, and human metapneumovirus (hMPV) . However, in a study that used multiplex PCR, in 30 of 32 patients in whom rhinovirus …
• 3. 肺移植後のウイルス感染症viral infections following lung transplantation [show details]
  …treatment of hMPV infections, as no studies have prospectively studied therapeutic interventions for hMPV in lung transplant recipients. Ribavirin has been used in a few cases of severe hMPV infection in …
• 4. 乳児や小児の細気管支炎：臨床的特徴および診断bronchiolitis in infants and children clinical features and diagnosis [show details]
  …can cause bronchiolitis, although croup is the more common presentation . Human metapneumovirus – Human metapneumovirus sometimes occurs in conjunction with other viral infections and has been identified …
• 5. 小児における肺炎：疫学、病因、および原因pneumonia in children epidemiology pathogenesis and etiology [show details]
  …than five years, in decreasing order of likelihood, include : Influenza A and B viruses. Human metapneumovirus is a common cause of lower respiratory tract infections (LRTIs) in children; most children …

English Journal

• Epidemiology of 11 respiratory RNA viruses in a cohort of hospitalized children in Riyadh, Saudi Arabia.

• Amer HM1,2, Alshaman MS1, Farrag MA1, Hamad ME1, Alsaadi MM3, Almajhdi FN1.
• Journal of medical virology.J Med Virol.2016 Jun;88(6):1086-91. doi: 10.1002/jmv.24435. Epub 2015 Dec 1.
• Respiratory tract infections are a principal cause of illness and mortality in children worldwide and mostly caused by viruses. In this study, the epidemiology of 11 respiratory RNA viruses was investigated in a cohort of hospitalized children at a tertiary referral center in Riyadh from February 20
• PMID 26595650

• Human Metapneumovirus Infections following Hematopoietic Cell Transplantation: Factors Associated with Disease Progression.

• Seo S1, Gooley TA2, Kuypers JM3, Stednick Z4, Jerome KR3, Englund JA5, Boeckh M6.
• Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.Clin Infect Dis.2016 May 3. pii: ciw284. [Epub ahead of print]
• BACKGROUND:  Human metapneumovirus (HMPV) is a newly identified pulmonary pathogen that can cause fatal lower respiratory tract disease (LRD) in hematopoietic cell transplant (HCT) recipients. Little is known about progression rates from upper respiratory tract infection to LRD and risk factors as
• PMID 27143659

• Pediatric Asthma and Viral Infection.

• Garcia-Garcia ML1, Calvo Rey C2, Del Rosal Rabes T3.
• Archivos de bronconeumologia.Arch Bronconeumol.2016 May;52(5):269-273. doi: 10.1016/j.arbres.2015.11.008. Epub 2016 Jan 4.
• Respiratory viral infections, particularly respiratory syncytial virus (RSV) and rhinovirus, are the most importance risk factors for the onset of wheezing in infants and small children. Bronchiolitis is the most common acute respiratory infection in children under 1year of age, and the most common
• PMID 26766408

Japanese Journal

• Characteristics of Human Metapneumovirus Infection Prevailing in Hospital Wards Housing Patients with Severe Disabilities

• Matsuda Shunji,Nakamura Masako,Hirano Eiko [他],Kiyota Naoko,Omura Tamaki,Suzuki Yumi,Noda Masahiro,Kimura Hirokazu
• Japanese Journal of Infectious Diseases 66(3), 195-200, 2013
• … However, the pathogens causing these infections remain unknown in approximately half of such epidemics. … Human metapneumovirus (HMPV) was detected from the nasal (and some pharyngeal) swabs from 17 patients. … Anti-HMPV antibody in the blood was positive in 95% of patients (151 of 159 inpatients), indicating no relation between HMPV infection and antibody titer but revealing recurrent infections. …
• NAID 130003381671

• Seasonal Patterns of Respiratory Syncytial Virus, Influenza A Virus, Human Metapneumovirus, and Parainfluenza Virus Type 3 Infections on the Basis of Virus Isolation Data between 2004 and 2011 in Yamagata, Japan

• Mizuta Katsumi,Abiko Chieko,Aoki Yoko [他],Ikeda Tatsuya,Matsuzaki Yoko,Itagaki Tsutomu,Katsushima Fumio,Katsushima Yuriko,Noda Masahiro,Kimura Hirokazu,Ahiko Tadayuki
• Japanese Journal of Infectious Diseases 66(2), 140-145, 2013
• … Most acute respiratory infections (ARIs) are thought to be associated with respiratory viruses that cause similar symptoms. … Respiratory syncytial virus (RSV), influenza A virus (FluA), human metapneumovirus (hMPV), and human parainfluenza virus type 3 (hPIV3) showed clear yearly seasonal patterns; …
• NAID 130003381656

• Molecular Epidemiology of Human Metapneumovirus from 2005 to 2011 in Fukui, Japan

• Nakamura Masako,Hirano Eiko,Ishiguro Fubito [他],Mizuta Katsumi,Noda Masahiro,Tanaka Ryota,Tsukagoshi Hiroyuki,Kimura Hirokazu
• Japanese Journal of Infectious Diseases 66(1), 56-59, 2013
• … To investigate the molecular epidemiology of human metapneumovirus (HMPV) infections in acute respiratory infections (ARI), we performed genetic analysis of the F gene in HMPV from patients with ARI in Fukui Prefecture from August 2005 to July 2011. …
• NAID 130003381642

Related Links

• Human metapneumovirus infections - Evidence-Based ...

Respiratory tract infections commonly are caused by viral pathogens, especially in young children. Respiratory syncytial virus (RSV) is the most common pathogen identified in these infections, followed historically by parainfluenza ...

• Human Metapneumovirus Infections in Children - Volume 14 ...

Human metapneumovirus (hMPV) is an important cause of lower respiratory tract infections in hospitalized children, but the age-related incidence and effect of hMPV in unselected children in the community have not been evaluated.

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★リンクテーブル★

リンク元	「ヒトメタニューモウイルス感染症」
関連記事	「human」「infection」「human metapneumovirus」「metapneumovirus」

「ヒトメタニューモウイルス感染症」

　　[★]

英

human metapneumovirus infections

関

ヒトメタニューモウイルス

疫学

• 2009/12-2010/5に呼吸器感染症で入院した小児患者258人(山形市立病院斉生館(山形県))のうちRSウイルス30%、hMPVウイルス18%を占めた。

• 生後6ヶ月から感染。2歳までに約半数、10際までにほぼ全ての小児が初感染。
• 春先に多い(2-4月)

11-12月：RSウイルス・パラインフルエンザウイルス

1-3月　：インフルエンザウイルス

2-4月　：ヒトメタニューモウイルス

• 発症のピークは1-2歳　　⇔　　RSウイルス感染症は1歳未満
• 感染経路：おそらく飛沫感染。集団完成する例が多い。

症状

• 1-3際の小児では38-39℃の発熱が4-5日持続。

臨床経過

• 1-3歳では咳がでると同日か翌日に発熱・鼻汁が出現する。発熱は5日前後、咳は1週間以上続く。気管支炎か下気道炎を起こす例もある。

身体所見

• 鼻汁：粘性強い　透明～乳白色

免疫

• 免疫を獲得しづらく、成人以降も何度も感染するが症状は軽くなる。

診断

• 他のウイルス感染症との鑑別は困難。疫学が頼り。

問診

• 家族内感染は？施設内感染は？

治療

• 対症療法：鼻汁除去、痰の排泄促進
• 細菌感染の続発による2峰性発熱を考慮。5日以上の発熱は細菌感染を考慮。

「human」

　　[★]

• n.

• ヒト

• adj.

• ヒトの、ヒト型の

関

ape、hominid、Hominidae、homo、Homo sapiens、human being、human race、human-type、man、Pongidae

　 　 　 　

「infection」

　　[★]

• n.

• 感染、伝染、感染症

関

contagion、infect、infectious disease、infestation、transmission、transmit

　 　 　 　 　 　 　

「human metapneumovirus」

　　[★] ヒトメタニューモウイルス HMPV

「metapneumovirus」

　　[★] メタニューモウイルス