English Journal

TRIM family: Pleiotropy and diversification through homomultimer and heteromultimer formation.

Napolitano LM, Meroni G.SourceCluster in Biomedicine, AREA Science Park, Trieste, Italy.
IUBMB life.IUBMB Life.2012 Jan;64(1):64-71. doi: 10.1002/iub.580. Epub 2011 Nov 30.
The TRIM family is composed of multidomain ubiquitin E3 ligases characterized by the presence of the N-terminal tripartite motif (RING, B-boxes, and coiled coil). TRIM proteins transfer the ubiquitin moiety to specific substrates but are also involved in ubiquitin-like modifications, in particular S
PMID 22131136

Homomultimerization of the reovirus p14 fusion-associated small transmembrane protein during transit through the ER-Golgi complex secretory pathway.

Corcoran JA, Clancy EK, Duncan R.SourceDepartment of Microbiology and Immunology, Dalhousie University, Halifax, NS B3H 4H7, Canada.
The Journal of general virology.J Gen Virol.2011 Jan;92(Pt 1):162-6. Epub 2010 Sep 22.
The reovirus fusion-associated small transmembrane (FAST) proteins are the smallest known viral membrane-fusion proteins. How these diminutive fusogens mediate cell-cell fusion and syncytium formation is unclear. Ongoing efforts are aimed at defining the roles of the FAST protein ecto-, endo- and tr
PMID 20861318