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1. 微小嚢胞性付属器癌 microcystic adnexal carcinoma
2. ユーイング肉腫ファミリーの腫瘍の臨床症状、病期分類、および予後因子 clinical presentation staging and prognostic factors of the ewing sarcoma family of tumors

English Journal

Cartilage differentiation in ependymoma: histogenetic considerations on a new case.

Coli A1, Novello M, Massimi L, Caldarelli M, Ranucci V, Lauriola L.Author information 1Department of Anatomic Pathology, Catholic University, Largo F. Vito 1, 00168, Rome, Italy, antonella.coli@rm.unicatt.it.AbstractThe presence of cartilage in gliomas is a very unusual finding and has been mainly reported in ependymomas and in astrocytomas. A derivation of cartilage from neuroepithelial cells through a neuroepithelial-mesenchymal transition or directly from blood vessel-associated multipotent stromal elements has been proposed. We herein describe a further case of ependymoma with the presence of cartilage in a child affected by a tumor in the posterior fossa. In this case, only the last recurrence, characterized by focal areas of anaplasia, contained a nodule of cartilage. The immunohistochemical expression of fibronectin, tenascin-C, and CD44 was investigated, and the possible role of these molecules in the process of cartilage formation is discussed. Moreover, the literature on the subject is reviewed.
Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery.Childs Nerv Syst.2014 Jan 22. [Epub ahead of print]
The presence of cartilage in gliomas is a very unusual finding and has been mainly reported in ependymomas and in astrocytomas. A derivation of cartilage from neuroepithelial cells through a neuroepithelial-mesenchymal transition or directly from blood vessel-associated multipotent stromal elements
PMID 24448879

Expression of cytokeratin 20 indicates invasive histological phenotype in poorly differentiated colorectal adenocarcinoma.

Imai Y1, Yamagishi H, Fukuda K, Okamura T, Ono Y, Ban S, Inoue T, Ueda Y.Author information 1Department of Pathology, Dokkyo Medical University Koshigaya Hospital, 2-1-50 Minami-Koshigaya, Koshigaya, Saitama 343-8555, Japan. yimai@s3.dion.ne.jp.AbstractBACKGROUND/AIM: Cytokeratin (CK) 20 expression is an independent prognostic factor of poorly differentiated adenocarcinoma (PDA) of the colon and rectum. We aimed to investigate the mechanism of its involvement through a clinicopathological study.
Anticancer research.Anticancer Res.2014 Jan;34(1):159-67.
BACKGROUND/AIM: Cytokeratin (CK) 20 expression is an independent prognostic factor of poorly differentiated adenocarcinoma (PDA) of the colon and rectum. We aimed to investigate the mechanism of its involvement through a clinicopathological study.PATIENTS AND METHODS: We analyzed 156 surgically rese
PMID 24403457

Smooth muscle tumors of soft tissue and non-uterine viscera: biology and prognosis.

Miettinen M.Author information National Cancer Institute, Laboratory of Pathology, Bethesda, MD, USA.AbstractSmooth muscle tumors are here considered an essentially dichotomous group composed of benign leiomyomas and malignant leiomyosarcomas. Soft tissue smooth muscle tumors with both atypia and mitotic activity are generally diagnosed leiomyosarcomas acknowledging potential for metastasis. However, lesions exist that cannot be comfortably placed in either category, and in such cases the designation 'smooth muscle tumor of uncertain biologic potential' is appropriate. The use of this category is often necessary with limited sampling, such as needle core biopsies. Benign smooth muscle tumors include smooth muscle hamartoma and angioleiomyoma. A specific category of leiomyomas are estrogen-receptor positive ones in women. These are similar to uterine leiomyomas and can occur anywhere in the abdomen and abdominal wall. Leiomyosarcomas can occur at any site, although are more frequent in the retroperitoneum and proximal extremities. They are recognized by likeness to smooth muscle cells but can undergo pleomorphic evolution ('dedifferentiation'). Presence of smooth muscle actin is nearly uniform and desmin-positivity usual. This and the lack of KIT expression separate leiomyosarcoma from GIST, an important problem in abdominal soft tissues. EBV-associated smooth muscle tumors are a specific subcategory occurring in AIDS or post-transplant patients. These tumors can have incomplete smooth muscle differentiation but show nuclear EBER as a diagnostic feature. In contrast to many other soft tissue tumors, genetics of smooth muscle tumors are poorly understood and such diagnostic testing is not yet generally applicable in this histogenetic group. Leiomyosarcomas are known to be genetically complex, often showing 'chaotic' karyotypes including aneuploidy or polyploidy, and no recurrent tumor-specific translocations have been detected.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc.Mod Pathol.2014 Jan;27 Suppl 1:S17-29. doi: 10.1038/modpathol.2013.178.
Smooth muscle tumors are here considered an essentially dichotomous group composed of benign leiomyomas and malignant leiomyosarcomas. Soft tissue smooth muscle tumors with both atypia and mitotic activity are generally diagnosed leiomyosarcomas acknowledging potential for metastasis. However, lesio
PMID 24384850

Japanese Journal

2SC-04 器官形成を支える細胞機能の動的解析(2SC 一個体イメージング,日本生物物理学会第49回年会(2011年度))

倉永英里奈
生物物理 51(SUPPLEMENT_1), S16, 2011-08-15
NAID 110008902908

Caspase signaling in animal development

Kuranaga Erina
Development, growth & differentiation 53(2), 137-148, 2011-02-01
NAID 10027899646

Situs inversus in a patient with nevoid basal cell carcinoma syndrome: a histogenetic relationship?

Gupta Monika,Das Debdutta,Mittal Amit,Kaur Harkamal,Malhotra Aayush
Journal of Oral Science 53(2), 253-256, 2011
Nevoid basal cell carcinoma syndrome (NBCCS) is an uncommon autosomal dominant inherited disorder with high penetrance and variable expressivity. It affects multiple organ systems, including the stoma …
NAID 130000834368