histamine receptor antagonist

出典: meddic

specific agents

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2012/10/19 09:10:21」(JST)

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  • Serotonin toxicity in aripiprazole augmentation.
  • Primeau M, Pomeraniec F, Wallace DM.
  • The Journal of neuropsychiatry and clinical neurosciences.J Neuropsychiatry Clin Neurosci.2012 Dec 1;24(1):E36-7.
  • PMID 22450642
  • H(1)-histamine receptors in the amygdala are involved in emotional memory but do not mediate anxiety-related behaviors in mice submitted to EPM testing.
  • Serafim KR, Gianlorenço AC, Daher FP, Mattioli R.SourceLaboratory of Neuroscience, Physiotherapy Department, Center of Biological Sciences and Health, Federal University of Sao Carlos, Rod. Washington Luis, Km 235, 13565-905 Sao Carlos, Brazil.
  • Brain research bulletin.Brain Res Bull.2012 Oct 1;89(1-2):1-7. Epub 2012 Jul 6.
  • This study investigated the role of amygdala H(1) receptors in state-dependent memory deficits induced by l-histidine (LH). Tests using an elevated plus-maze (EPM) were performed on two consecutive days: Trial 1 (T1) and Trial 2 (T2). Before each trial, mice were intraperitoneally (IP) injected with
  • PMID 22772356


  • The Role of Histamine H1 and H4 Receptors in Atopic Dermatitis: From Basic Research to Clinical Study
  • ,
  • Allergology International 63(4), 533-542, 2014
  • Histamine plays important roles in inflammation and nervous irritability in allergic disorders, including atopic dermatitis (AD). … It has been shown to regulate the expression of pruritic factors, such as nerve growth factor and semaphorin 3A, in skin keratinocytes via histamine H1 receptor (H1R). … Furthermore, H1R antagonist reduced the level of IL-31, a cytokine involving the skin barrier and pruritus, in chronic dermatitis lesions in NC/Nga mice and patients with AD. …
  • NAID 130004705221
  • P7-004  Histamine inhibits differentiation of skin fibroblasts into myofibroblasts
  • 林 琳,澤向 範文,山形 熏,山岡 邦宏,中野 和久,中山田 真吾,田中 良哉
  • 日本臨床免疫学会会誌 37(4), 362b-362b, 2014
  • … 【Background】Histamine (HA) and TGF-β, major mediators secreted by mast cells are involved in skin inflammation and systemic sclerosis. … 【Methods】Skin fibroblasts (SFBs) were stimulated with TGF-β, HA, or HA receptor antagonists. … 【Results】Expression of H1-receptor (H1R) and H2-receptor (H2R) were detectable in SFBs at both mRNA and protein level. …
  • NAID 130004694292
  • 緊急消化管内視鏡検査を要した血液透析症例:—当院における過去6年間の臨床的検討—
  • 宮澤 晴久,大河原 晋,伊藤 聖学 [他],植田 裕一郎,賀来 佳男,平井 啓之,星野 太郎,名畑 あおい,森 穂波,吉田 泉,宮谷 博幸,吉田 行雄,田部井 薫
  • 日本透析医学会雑誌 47(6), 351-357, 2014
  • 【目的】当院で緊急消化管内視鏡検査を要した症例をretrospectiveに集計し臨床的背景を明らかにすること. 【対象と方法】対象は2005年1月から2010年12月までの6年間に消化管出血もしくはその疑いのために当院で緊急消化管内視鏡検査を施行した維持血液透析 (HD) 症例44例. 各症例で緊急消化管内視鏡検査施行前後の臨床経過について解析を行った. 【結果】緊急内視鏡検査は重複例を含めて, …
  • NAID 130004542537


histamine receptor antagonists H 1 receptor antagonist, H 2 receptor antagonist Therapeutics A family of agents that counter histamine activity, which are used to treat conditions linked to ↑ histamine release–eg, mast cell disease ...
Histamine antagonist A histamine antagonist is an agent that inhibits action of histamine via histamine receptors. H 1 antihistamines are used as treatment for symptoms of allergies such as runny nose. Allergies are caused by an ...


Animation on histamine release and Histamine H1 Receptor Antagonist histamine 2 receptor antagonist slide 15Histamine Antagonists (Antihistamines)065_12_KB-Histamine-Receptors-400x300px Histamine H1 Receptor Antagonist

関連記事antagonist」「histamine」「receptor」「histamine receptor


  [★] 拮抗薬

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「a drug that neutralizes or counteracts the effects of another drug」

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「a muscle that relaxes while another contracts; "when bending the elbow the triceps are the antagonist"」

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  [★] ヒスタミン

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「amine formed from histidine that stimulates gastric secretions and dilates blood vessels; released by the human immune system during allergic reactions」

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  [★] 受容体

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「a cellular structure that is postulated to exist in order to mediate between a chemical agent that acts on nervous tissue and the physiological response」

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「=sense organ / 受信装置」

histamine receptor」