ヒスタミナーゼ
- 関
- copper amine oxidase、copper-containing amine oxidase、diamine oxidase
WordNet
- enzyme that acts as a catalyst in converting histidine to histamine
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/04/21 19:13:23」(JST)
[Wiki en表示]
| Diamine oxidase |
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Ribbon representation of human diamine oxidase.[1]
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| Identifiers |
| EC number |
1.4.3.22 |
| Databases |
| IntEnz |
IntEnz view |
| BRENDA |
BRENDA entry |
| ExPASy |
NiceZyme view |
| KEGG |
KEGG entry |
| MetaCyc |
metabolic pathway |
| PRIAM |
profile |
| PDB structures |
RCSB PDB PDBe PDBsum |
| Gene Ontology |
AmiGO / EGO |
| Search |
| PMC |
articles |
| PubMed |
articles |
| NCBI |
proteins |
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Diamine oxidase, also known as histaminase, is an enzyme (EC 1.4.3.22) involved in the metabolism, oxidation, and inactivation of histamine in animals. Highest content is observed in the digestive tract and placenta.[2]
References
- ^ PDB: 3HI7; McGrath AP, Hilmer KM, Collyer CA, Shepard EM, Elmore BO, Brown DE, Dooley DM, Guss JM (Oct 2009). "Structure and inhibition of human diamine oxidase". Biochemistry 48 (41): 9810–22. doi:10.1021/bi9014192. PMC: 2791411. PMID 19764817. ; rendered with PyMOL
- ^ Agúndez JA, Ayuso P, Cornejo-García JA, Blanca M, Torres MJ, Doña I, Salas M, Blanca-López N, Canto G, Rondon C, Campo P, Laguna JJ, Fernández J, Martínez C, García-Martín E (2012). "The diamine oxidase gene is associated with hypersensitivity response to non-steroidal anti-inflammatory drugs". PLOS ONE 7 (11): e47571. doi:10.1371/journal.pone.0047571. PMID 23152756.
External links
- Amine Oxidase (Copper-Containing) at the US National Library of Medicine Medical Subject Headings (MeSH)
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Enzymes involved in neutrotransmission
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| monoamine |
| histidine → histamine |
| anabolism: |
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| catabolism: |
- Histamine N-methyltransferase
- Diamine oxidase
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| tyrosine→dopamine→epinephrine |
| anabolism: |
- Tyrosine hydroxylase
- Aromatic L-amino acid decarboxylase
- Dopamine beta-hydroxylase
- Phenylethanolamine N-methyltransferase
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| catabolism: |
- Catechol-O-methyl transferase
- Monoamine oxidase
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| glutamate→GABA |
| anabolism: |
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| catabolism: |
- 4-aminobutyrate transaminase
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| tryptophan→serotonin→melatonin |
- Tryptophan hydroxylase
- Aromatic L-amino acid decarboxylase
- Aralkylamine N-acetyltransferase
- Acetylserotonin O-methyltransferase
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| arginine→NO |
- Nitric oxide synthase (NOS1, NOS2, NOS3)
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| choline→Acetylcholine |
| anabolism: |
- Choline acetyltransferase
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| catabolism: |
- Cholinesterase (Acetylcholinesterase, Butyrylcholinesterase)
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CH-NH2 oxidoreductases (EC 1.4) - primarily amino acid oxidoreductases
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| 1.4.1: NAD/NADP acceptor |
- Glutamate dehydrogenase
- Glutamate synthase (NADPH)
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| 1.4.3: oxygen acceptor |
- D-amino acid oxidase
- Amine oxidase (Copper-containing (Lysyl
- Diamine
- Primary-amine)) (Flavin-containing (Monoamine)))
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| 1.4.4: disulfide acceptor |
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| 1.4.99: other acceptors |
- D-amino acid dehydrogenase
- Amine dehydrogenase
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English Journal
- Long non-coding RNA AOC4P suppresses hepatocellular carcinoma metastasis by enhancing vimentin degradation and inhibiting epithelial-mesenchymal transition.
- Wang TH1, Lin YS2, Chen Y1, Yeh CT3, Huang YL2, Hsieh TH1, Shieh TM4, Hsueh C1,2, Chen TC1,2.
- Oncotarget.Oncotarget.2015 Sep 15;6(27):23342-57.
- Increasing evidence indicates that long non-coding RNAs (lncRNAs) regulate diverse cellular processes, including cell growth, differentiation, apoptosis, and cancer progression. However, the function of lncRNAs in the progression of hepatocellular carcinoma (HCC) remains largely unknown. We performe
- PMID 26160837
- Vascular adhesion protein-1: Role in human pathology and application as a biomarker.
- Pannecoeck R1, Serruys D, Benmeridja L, Delanghe JR, Geel NV, Speeckaert R, Speeckaert MM.
- Critical reviews in clinical laboratory sciences.Crit Rev Clin Lab Sci.2015 Aug 19:1-17. [Epub ahead of print]
- Vascular adhesion protein-1 (VAP-1) is a member of the copper-containing amine oxidase/semicarbazide-sensitive amine oxidase (AOC/SSAO) enzyme family. SSAO enzymes catalyze oxidative deamination of primary amines, which results in the production of the corresponding aldehyde, hydrogen peroxide and a
- PMID 26287391
- Association of plasma diamine oxidase and intestinal fatty acid-binding protein with severity of disease in patient with heat stroke.
- Zhang L1, Fan X2, Zhong Z1, Xu G3, Shen J4.
- The American journal of emergency medicine.Am J Emerg Med.2015 Jul;33(7):867-71. doi: 10.1016/j.ajem.2015.01.047. Epub 2015 Feb 2.
- OBJECTIVES: The aim of this study was to describe the role of intestinal fatty acid-binding protein (iFABP) and allergy-related diamine oxidase (DAO) in patients with heat stroke (HS).METHODS: A total of 10 patients with HS in intensive care unit and 10 healthy volunteers were enrolled in this study
- PMID 25913083
Japanese Journal
- An Outbreak of Histamine Poisoning after Ingestion of the Ground Saury Paste in Eight Patients Taking Isoniazid in Tuberculous Ward
- MIKI Makoto,ISHIKAWA Tetsuko,OKAYAMA Hiroshi
- Internal medicine 44(11), 1133-1136, 2005-11-01
- … We speculated that those allergy-like symptoms were due to both the increased histamine in the food made with the saury under poor storage conditions and the patients’ reduced histaminase activities due to INH. …
- NAID 10016885922
- Histamine Poisoning after Ingestion of Spoiled Raw Tuna in a Patient Taking Isoniazid
- MORINAGA Shinichi,KAWASAKI Akira,HIRATA Hitoshi,SUZUKI Shinji,MIZUSHIMA Yutaka
- Internal medicine 36(3), 198-200, 1997-03
- … eating spoiled raw tuna and at the same time being on a course of INH, a potent histaminase inhibitor. …
- NAID 10007005766
Related Links
- Histaminase definition, an enzyme that catalyzes the decomposition of histamine, used in treating allergies. See more. Thesaurus Translate Puzzles & Games Reference Word of the Day Blog Slideshows Apps by Dictionary ...
- an enzyme found in the animal digestive system, capable of inactivating histamine Origin of histaminase histamin(e)- + -ase
★リンクテーブル★
[★]
- 関
- copper-containing amine oxidase、diamine oxidase、histaminase
[★]
- 関
- copper amine oxidase、copper-containing amine oxidase、histaminase
- 同
- DAO
- 同
- DAO
[★]
- 関
- copper amine oxidase、diamine oxidase、histaminase
[★]
- 英
- histaminase
- 関
- 銅含有アミン酸化酵素、ジアミン酸化酵素