出典: meddic



  • A novel method for separation of caseins from milk by phosphates precipitation.
  • Yen CH1, Lin YS, Tu CF.
  • Preparative biochemistry & biotechnology.Prep Biochem Biotechnol.2015 Jan 2;45(1):18-32. doi: 10.1080/10826068.2013.877030.
  • Milk protein of farm animals is difficult to isolate because of the presence of casein micelles, which are hard to separate from whey by using centrifugation or filtration. Insoluble casein micelles also create an obstacle for purification instruments to operate efficiently. The conventional method,
  • PMID 24372141
  • Poly(lactic-co-glycolic) acid microspheres encapsulated in Pluronic F-127 prolong hirudin delivery and improve functional recovery from a demyelination lesion.
  • Sellers DL1, Kim TH2, Mount CW2, Pun SH2, Horner PJ3.
  • Biomaterials.Biomaterials.2014 Oct;35(31):8895-902. doi: 10.1016/j.biomaterials.2014.06.051. Epub 2014 Jul 23.
  • Components of the blood have been proposed as potential therapeutic targets for improving cellular regeneration after injury and neurodegenerative disease. In this work, thrombin is shown to increase endogenous neural progenitor proliferation in the intact murine spinal cord. A local injection of he
  • PMID 25064804
  • Genetic variants and evolutionary analyses of heparin cofactor II.
  • Kumar A1, Bhandari A2, Sarde SJ3, Goswami C4.
  • Immunobiology.Immunobiology.2014 Sep;219(9):713-28. doi: 10.1016/j.imbio.2014.05.003. Epub 2014 May 27.
  • Heparin cofactor II (HCII) belongs to serpin superfamily and it acts as a thrombin inhibitor in the coagulation cascade, in a glycosaminoglycan-dependent pathway using the release of a sequestered hirudin-like N-terminal tail for interaction with thrombin. This serpin belongs to multiple member grou
  • PMID 24950623


  • 1P-072 3つのSS結合をもつヒルジンの酸化的リフォールディング経路の解析(蛋白質・物性(1),第46回日本生物物理学会年会)
  • Thrombin-Stimulated Proliferation of Cultured Human Synovial Fibroblasts Through Proteolytic Activation of Proteinase-Activated Receptor-1
  • Journal of pharmacological sciences 108(1), 104-111, 2008-09-20
  • NAID 10024322567
  • A development of LC-MS method combining ultrafiltration and lyophilization for determination of r-RGD-Hirudin in human serum
  • Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 870(1), 27-31, 2008-07-01
  • NAID 10028002411



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