WordNet

in or to a high position, amount, or degree; "prices have gone up far too high"
a state of altered consciousness induced by alcohol or narcotics; "they took drugs to get a high on"
a state of sustained elation; "Im on a permanent high these days"
an air mass of higher than normal pressure; "the east coast benefits from a Bermuda high"
a lofty level or position or degree; "summer temperatures reached an all-time high"
a high place; "they stood on high and observed the countryside"; "he doesnt like heights" (同)heights
at a great altitude; "he climbed high on the ladder" (同)high up
used of sounds and voices; high in pitch or frequency (同)high-pitched
happy and excited and energetic (同)in high spirits
slightly and pleasantly intoxicated from alcohol or a drug (especially marijuana) (同)mellow
in a rich manner; "he lives high" (同)richly, luxuriously
(literal meaning) being at or having a relatively great or specific elevation or upward extension (sometimes used in combinations like `knee-high'
far up toward the source; "he lives high up the river"
greater than normal in degree or intensity or amount; "a high temperature"; "a high price"; "the high point of his career"; "high risks"; "has high hopes"; "the river is high"; "he has a high opinion of himself"
(physics) a thermodynamic quantity equivalent to the capacity of a physical system to do work; the units of energy are joules or ergs; "energy can take a wide variety of forms" (同)free_energy
a healthy capacity for vigorous activity; "jogging works off my excess energy"; "he seemed full of vim and vigor" (同)vim, vitality
any source of usable power; "the DOE is responsible for maintaining the energy policy"
an imaginative lively style (especially style of writing); "his writing conveys great energy"; "a remarkable muscularity of style" (同)muscularity, vigor, vigour, vim
enterprising or ambitious drive; "Europeans often laugh at American energy" (同)push, get-up-and-go
forceful exertion; "he plays tennis with great energy"; "hes full of zip" (同)vigor, vigour, zip
(medicine) the act of caring for someone (as by medication or remedial training etc.); "the quarterback is undergoing treatment for a knee injury"; "he tried every treatment the doctors suggested"; "heat therapy gave the best relief"
a body having finite mass and internal structure but negligible dimensions (同)subatomic_particle
a function word that can be used in English to form phrasal verbs

PrepTutorEJDIC

『高い』,高い所にある / 《数の後に置いて》高さが…ある / (数量・程度などが標準より)『高い』,大きい,激しい / (身分・地位が)『高い』,高貴な / 『気高い』,高潔な / (声の調子が)『高い』,鋭い / 値段の高い,金の掛かる,ぜいたくな / 楽しい,陽気な,上得意の / (時・季節が)盛りの,たけなわの / (色が)濃い,赤い / 《話》(酒・麻薬などに)酔って / 『高く』,高い所に / (価値・程度などが)高く,高度に,激しく / 〈C〉《話》高水準,高値 / 〈U〉(自動車の)高速ギア / 〈C〉《話》(麻薬などによる)酔った状態
(一般的な力としての)『精力』,気力,元気 / (個人の)精力,活動力 / エネルギー
(病気の)治療,療法 / =psychotherapy
小片,(ごく)少量,微量 / 粒子 / 不変化詞(冠詞・前置詞・接続詞・感嘆詞など語形変化のない語);小詞,小辞
《話》(あいさつとして)『やあ』,こんにちは / 《英》(注意を促す発声として)おい,ちょっと(hey)

UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

1. 思春期における食物エネルギー所要量 dietary energy requirements in adolescents
2. 唾液腺腫瘍：限局性疾患の治療 salivary gland tumors treatment of locoregional disease
3. Adjuvant radiation therapy for high-grade gliomas
4. 眼ぶどう膜および結膜の悪性黒色腫 uveal and conjunctival melanomas
5. 成人における肥満：食事療法 obesity in adults dietary therapy

English Journal

New challenges in high-energy particle radiobiology.

Durante M.Author information GSI Helmholtz Center for Heavy Ion Research, Biophysics Department, Darmstadt, Germany.AbstractDensely ionizing radiation has always been a main topic in radiobiology. In fact, α-particles and neutrons are sources of radiation exposure for the general population and workers in nuclear power plants. More recently, high-energy protons and heavy ions attracted a large interest for two applications: hadrontherapy in oncology and space radiation protection in manned space missions. For many years, studies concentrated on measurements of the relative biological effectiveness (RBE) of the energetic particles for different end points, especially cell killing (for radiotherapy) and carcinogenesis (for late effects). Although more recently, it has been shown that densely ionizing radiation elicits signalling pathways quite distinct from those involved in the cell and tissue response to photons. The response of the microenvironment to charged particles is therefore under scrutiny, and both the damage in the target and non-target tissues are relevant. The role of individual susceptibility in therapy and risk is obviously a major topic in radiation research in general, and for ion radiobiology as well. Particle radiobiology is therefore now entering into a new phase, where beyond RBE, the tissue response is considered. These results may open new applications for both cancer therapy and protection in deep space.
The British journal of radiology.Br J Radiol.2014 Mar;87(1035):20130626. doi: 10.1259/bjr.20130626.
Densely ionizing radiation has always been a main topic in radiobiology. In fact, α-particles and neutrons are sources of radiation exposure for the general population and workers in nuclear power plants. More recently, high-energy protons and heavy ions attracted a large interest for two applicati
PMID 24198199

Project for the development of the linac based NCT facility in University of Tsukuba.

Kumada H1, Matsumura A2, Sakurai H3, Sakae T3, Yoshioka M4, Kobayashi H4, Matsumoto H4, Kiyanagi Y5, Shibata T6, Nakashima H6.Author information 1Proton Medical Research Centre, University of Tsukuba, Tsukuba, Ibaraki 305-8575, Japan. Electronic address: kumada@pmrc.tsukuba.ac.jp.2Department of Neurosurgery, University of Tsukuba, Tsukuba, Ibaraki 305-8575, Japan.3Proton Medical Research Centre, University of Tsukuba, Tsukuba, Ibaraki 305-8575, Japan.4High Energy Accelerator Research Organization, Tsukuba, Ibaraki 305-0801, Japan.5Laboratory of Quantum Beam System, Hokkaido University, Sapporo, Hokkaido 060-0808, Japan.6J-PARC Center, Japan Atomic Energy Agency, Tokai, Ibaraki 319-1195, Japan.AbstractA project team headed by University of Tsukuba launched the development of a new accelerator based BNCT facility. In the project, we have adopted Radio-Frequency Quadrupole (RFQ)+Drift Tube Linac (DTL) type linac as proton accelerators. Proton energy generated from the linac was set to 8MeV and average current was 10mA. The linac tube has been constructed by Mitsubishi Heavy Industry Co. For neutron generator device, beryllium is selected as neutron target material; high intensity neutrons are generated by the reaction with beryllium and the 80kW proton beam. Our team chose beryllium as the neutron target material. At present beryllium target system is being designed with Monte-Carlo estimations and heat analysis with ANSYS. The neutron generator consists of moderator, collimator and shielding. It is being designed together with the beryllium target system. We also acquired a building in Tokai village; the building has been renovated for use as BNCT treatment facility. It is noteworthy that the linac tube had been installed in the facility in September 2012. In BNCT procedure, several medical devices are required for BNCT treatment such as treatment planning system, patient positioning device and radiation monitors. Thus these are being developed together with the linac based neutron source. For treatment planning system, we are now developing a new multi-modal Monte-Carlo treatment planning system based on JCDS. The system allows us to perform dose estimation for BNCT as well as particle radiotherapy and X-ray therapy. And the patient positioning device can navigate a patient to irradiation position quickly and properly. Furthermore the device is able to monitor movement of the patient׳s position during irradiation.
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine.Appl Radiat Isot.2014 Feb 22. pii: S0969-8043(14)00070-0. doi: 10.1016/j.apradiso.2014.02.018. [Epub ahead of print]
A project team headed by University of Tsukuba launched the development of a new accelerator based BNCT facility. In the project, we have adopted Radio-Frequency Quadrupole (RFQ)+Drift Tube Linac (DTL) type linac as proton accelerators. Proton energy generated from the linac was set to 8MeV and aver
PMID 24637084

Dreams, themes and particle beams-an oncologist's perspective on technology trickle-down from the LHC.

Jena R.Author information Cambridge University Hospitals NHS Foundation Trust, Addenbrooke's Hospital, Cambridge, UK.AbstractAbstract 11 years ago, the European Network for Light Ion Therapy (ENLIGHT) was established as a multidisciplinary network of engineers, physicists and clinicians with a common interest in the development of hadron therapy in Europe. ENLIGHT is coordinated from the European Centre for Nuclear Research (CERN), the home of the Large Hadron Collider. The network has evolved into a mature platform for research, with more than 100 researchers working in CERN and its allied research centres. One of the benefits of hosting this network at CERN is the ability to translate hardware and software developments, originally developed in the High Energy Physics domain, into clinical applications. From the perspective of a clinical radiation oncologist within the network, this commentary reviews the ways in which leading edge technological developments in detectors and solid state physics, Monte-Carlo simulation, grid computing and accelerator design have trickled down into real-world clinical applications.
The British journal of radiology.Br J Radiol.2014 Feb 3:20130828. [Epub ahead of print]
Abstract 11 years ago, the European Network for Light Ion Therapy (ENLIGHT) was established as a multidisciplinary network of engineers, physicists and clinicians with a common interest in the development of hadron therapy in Europe. ENLIGHT is coordinated from the European Centre for Nuclear Resear
PMID 24593272

Japanese Journal

粒子線治療における化学の役割 : 高エネルギー重粒子線のトラック構造と生成物収率 (特集第41回放射線による制癌シンポジウム : 基礎と臨床の対話) -- (粒子線治療のための物理学,化学,生物学)

山下真一
癌の臨床 = Japanese journal of cancer clinics 59(2), 177-182, 2013-04
NAID 40019701913

重粒子線治療用高エネルギーイオンによるトラック構造の微視的研究

平山悟,魚住裕介,福留翔吾
バイオメディカル・ファジィ・システム学会誌 14(1), 27-36, 2012-05-30
現在、がんに対する放射線療法として重粒子線治療が注目されている。本論文では、重粒子線の生物学的特性の解明や重粒子線治療の安全性向上に必要なイオントラック構造を微視的再現する事を目的として3次元モンテカルロコード作成を行った。最初に、水ターゲット中の二次電子追跡に必要な電子の反応断面積をMeV領域まで導出し、二次電子トラックを計算するプログラムを作成した。作成したプログラムで電子の飛程の計算値を検証 …
NAID 110009456990