herpetic gingivostomatitis

ヘルペス性歯肉口内炎

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2017/03/06 20:06:18」(JST)

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Gingivostomatitis
Classification and external resources
Specialty	infectious disease
ICD-10	A69.1, B00.2,
ICD-9-CM	054.2, 523.10
MedlinePlus	001052

Gingivostomatitis (also known as primary herpetic gingivostomatitis or orolabial herpes) is a combination of gingivitis and stomatitis, or an inflammation of the oral mucosa and gingiva. Herpetic gingivostomatitis is often the initial presentation during the first ("primary") herpes simplex infection. It is of greater severity than herpes labialis (cold sores) which is often the subsequent presentations. Primary herpetic gingivostomatitis is the most common viral infection of the mouth.

Primary herpetic gingivostomatitis (PHGS) represents the clinically apparent pattern of primary herpes simplex virus (HSV) infection, since the vast majority of other primary infections are symptomless. PHGS is caused predominantly by HSV-1 and affects mainly children. Prodromal symptoms, such as fever, anorexia, irritability, malaise and headache, may occur in advance of disease. The disease presents as numerous pin-head vesicles, which rupture rapidly to form painful irregular ulcerations covered by yellow–grey membranes. Sub-mandibular lymphadenitis, halitosis and refusal to drink are usual concomitant findings.

Symptoms

Herpes lesions on the gingiva.

The symptoms can be mild or severe and may include:

• Not able to chew or swallow
• Sores on the inside of the cheeks or gums
• Fever
• General discomfort, uneasiness, or ill feeling
• Very sore mouth with no desire to eat
• Halitosis (bad breath)

Differential Diagnosis

Gingivostomatitis symptoms in infants may wrongly be dismissed as teething. "Coincidentally, primary tooth eruption begins at about the time that infants are losing maternal antibody protection against the herpes virus. Also, reports on teething difficulties have recorded symptoms which are remarkably consistent with primary oral herpetic infection such as fever, irritability, sleeplessness, and difficulty with eating." "Younger infants with higher residual levels of antibodies would experience milder infections and these would be more likely to go unrecognized or be dismissed as teething difficulty."

Gingivostomatitis must also be differentiated from herpangina, another disease that also commonly causes ulcers in the oral cavity of children, but is caused by the Coxsackie A virus rather than a herpes virus. In herpangina, ulcers are usually isolated to the soft palate and anterior pillar of the mouth. In herpetic gingivostomatitis, lesions can be found in these locations, but they are almost always accompanied by ulcerations on the gums, lips, tongue or buccal mucosa and/or by hyperemia, hypertrophy or hemorrhage of the gums.

Treatment

Treatment includes fluid intake, good oral hygiene and gentle debridement of the mouth. In healthy individuals the lesions heal spontaneously in 7–14 days without scarring.

See also

• Acute necrotizing ulcerative gingivitis

References

External links

• Underlying Causes at wrongdiagnosis.com
• CDC Case Definition: Mercury (Elemental)

UpToDate Contents

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• 1. 若齢小児におけるヘルペス性歯肉口内炎 herpetic gingivostomatitis in young children
• 2. 免疫正常患者における単純ヘルペスウイルス1型感染の治療 treatment of herpes simplex virus type 1 infection in immunocompetent patients
• 3. 口腔病変 oral lesions
• 4. 手足口病およびヘルパンギーナ：概要 hand foot and mouth disease and herpangina an overview
• 5. 小児における口腔軟部組織病変 soft tissue lesions of the oral cavity in children

English Journal

• Severe acute disseminated encephalomyelitis with clinical findings of transverse myelitis after herpes simplex virus infection.

• Sarioglu B1, Kose SS2, Saritas S3, Kose E3, Kanik A3, Helvaci M3.
• Journal of child neurology.J Child Neurol.2014 Nov;29(11):1519-23. doi: 10.1177/0883073813513334. Epub 2014 Feb 13.
• BACKGROUND: ADEM is a central nervous disease that leads to myelin damage as a result of autoimmune response that develops after infections or vaccination. Herpes Simplex Virus (HSV) infection rarely leads to ADEM.PATIENT: 25-month-old male due to urinary retention, paradoxical respiration and muscl
• PMID 24525997

• Herpetic gingivostomatitis.

• Podder I1, Das A.
• Indian pediatrics.Indian Pediatr.2014 Sep;51(9):764.
• PMID 25228626

• X-linked adrenal hypoplasia congenita: a case report and ethical dilemma.

• Ismail HM1, Rincon M2.
• Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists.Endocr Pract.2014 Jul;20(7):e126-9. doi: 10.4158/EP14033.CR.
• OBJECTIVE: Our objective is to present the first case report of X-linked adrenal hypoplasia congenita in a child conceived by a donated egg and which also presented atypically, with initial mineralocorticoid deficiency.METHODS: Case report with literature review.RESULTS: A late preterm fraternal twi
• PMID 24641931

Japanese Journal

• 難治性潰瘍性口内炎が初発症状と考えられた急性型成人T細胞白血病の1例

• 松井 竜太郎,山口 孝二郎,田畑 雅士,副島 健太郎,向井 洋,杉原 一正
• 日本口腔外科学会雑誌 50(4), 251-254, 2004-04-20
• … The clinical diagnosis was herpetic gingivostomatitis.<BR>After admission, the patient received systemic antiviral agents (aciclovir), and corticosteroid ointment was applied to the oral lesions. …
• NAID 10018620229

• 歯周病の分類

• 日本歯周病学会会誌 43(3), 319-322, 2001
• 1. 歯肉疾患<BR>A. プラーク起因性歯肉疾患<BR>1. プラーク単独性歯肉炎<BR>a. その他の局所因子を含まない<BR>b. その他の局所因子を含む (皿A参照)<BR>2. 全身因子関連歯肉疾患<BR>a. 内分泌関連<BR>1) 思春期性歯肉炎<BR>2) 月経性歯肉炎<BR&gt …
• NAID 130001471673

Related Pictures

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★リンクテーブル★

リンク元	「単純ヘルペス性急性歯肉口内炎」「ヘルペス性歯肉口内炎」「疱疹性歯肉口内炎」「oral herpes simplex」

「単純ヘルペス性急性歯肉口内炎」

　　[★]

英

acute herpes simplex gingivostomatitis

関

ヘルペス性口内炎 herpetic stomatitis、ヘルペス性歯肉口内炎 herpetic gingivostomatitis、急性ヘルペス性歯肉口内炎 acute herpetic gingivostomatitis

「ヘルペス性歯肉口内炎」

　　[★]

英

herpetic gingivostomatitis

関

疱疹性歯肉口内炎、ヘルペス性口内炎、口腔単純ヘルペス

「疱疹性歯肉口内炎」

　　[★]

英

herpetic gingivostomatitis

ラ

gingivostomatitis herpetica

関

ヘルペス性歯肉口内炎、口内炎

「oral herpes simplex」

　　[★]

口腔単純ヘルペス

関

herpetic gingivostomatitis、herpetic stomatitis