hepatic encephalopathy

出典: meddic


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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2016/02/24 15:26:17」(JST)

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  • Valproic acid-induced hyperammonemic encephalopathy - a potentially fatal adverse drug reaction.
  • Sousa C.SourcePharmacy, Hospital de Faro, EPE, Rua Leao Penedo, Faro, 8000-386 Portugal.
  • SpringerPlus.Springerplus.2013 Dec;2(1):13. Epub 2013 Jan 15.
  • BACKGROUND: A patient with an early diagnosed epilepsy Valproic acid is one of the most widely used antiepileptic drugs. Hyperammonemic encephalopathy is a rare, but potentially fatal, adverse drug reaction to valproic acid.CASE DESCRIPTION: A patient with an early diagnosed epilepsy, treated with v
  • PMID 23451336
  • Hydrogen: A promising novel treatment for hepatic encephalopathy?
  • Qu J, Lü X.SourceWest China Hospital, Sichuan University, Chengdu, China. Electronic address: ganranke2@126.com.
  • Free radical biology & medicine.Free Radic Biol Med.2013 Oct;63:457-8. doi: 10.1016/j.freeradbiomed.2013.05.032. Epub 2013 Jun 3.
  • PMID 23743290
  • Protective role of antioxidants on thioacetamide-induced acute hepatic encephalopathy: Biochemical and Ultrastructural study.
  • Mustafa HN, El Awdan SA, Hegazy GA.SourceAnatomy Department, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia. Electronic address: hesham977@hotmail.com.
  • Tissue & cell.Tissue Cell.2013 Oct;45(5):350-62. doi: 10.1016/j.tice.2013.06.001. Epub 2013 Jul 19.
  • Thioacetamide (TAA) has been used in development of animal models of acute hepatic encephalopathy (AHE). This experimental study was designed to evaluate effects of oral administration of vitamin C, vitamin E and their combination on liver and brain enzymes and their histologic and ultrastructure ch
  • PMID 23876406


  • 症例報告 血液濾過透析を含めた集学的治療により肝性脳症が管理できた維持血液透析患者の1例
  • 西川 真那,島田 典明,永山 泉 [他]
  • 日本透析医学会雑誌 48(3), 199-205, 2015-03
  • NAID 40020420745
  • 急性肝不全に対する人工肝補助療法(<特集>小児疾患とアフェレシス)
  • 服部 憲幸,安部 隆三,織田 成人
  • 日本アフェレシス学会雑誌 34(1), 64-69, 2015-02-28
  • … Although pediatric liver transplants have a high survival rate, fatal complications such as bleeding, cerebral edema due to hepatic encephalopathy, or infection make it difficult to wait for recovery or transplantation. … Artificial liver support using apheresis is effective for recovery from coma due to hepatic encephalopathy, and enables to keep patients in good general status. …
  • NAID 110009922598
  • The changes in treatment strategies in ABOi living donor liver transplantation for acute liver failure
  • Yasuda Mitsuhiro,Ikegami Toru,Imai Daisuke,Wang Huanlin,Bekki Yuki,Itoh Shinji,Yoshizumi Tomoharu,Soejima Yuji,Shirabe Ken,Maehara Yoshihiko
  • The Journal of Medical Investigation 62(3.4), 184-187, 2015
  • … local infusion (hepatic artery)+rituximab+PE, Case #3 and #4; … Local infusion was abandoned since Case #3, because Case #1 had portal vein thrombosis resulting in graft necrosis and Case #2 had hepatic artery dissection. … Thus, the most recent protocol for ABOi-LDLT is that rituximab is given 2 weeks before LDLT, followed by high-flow continuous hemodiafiltration to obstacle hepatic encephalopathy until LDLT. …
  • NAID 130005099144


Investigations [edit] The diagnosis of hepatic encephalopathy can only be made in the presence of confirmed liver disease (types A and C) or a portosystemic shunt (type B), as its symptoms are similar to those encountered in other encephalopathies
Causes The exact cause of hepatic encephalopathy is unknown. Hepatic encephalopathy is brought on by disorders that affect the liver. These include: Conditions that reduce liver function (such as cirrhosis or hepatitis)



リンク元肝性脳症」「portosystemic encephalopathy



hepatic encephalopathy


  • 肝不全に伴う脳症(精神症状を呈する)


  • 肝硬変、劇症肝炎
  • 劇症肝炎
  • 肝細胞機能不全
  • 肝硬変
  • 肝細胞機能不全 + 門脈-大循環短絡


  • 種々の原疾患により肝性脳症を来す物質が蓄積、中枢神経に移行して脳症を発症する




portosystemic encephalopathy」



hepatic comahepatic encephalopathyportal-systemic encephalopathy



  • adj.
  • 肝臓の、肝性の、肝の

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「pertaining to or affecting the liver; "hepatic ducts"; "hepatic cirrhosis"」

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