halcinonide

Halcinonide
Systematic (IUPAC) name
	(4aS,4bR,5S,6aS,6bS,9aR,10aS,10bS)-6b-(chloroacetyl)-4b-fluoro-5-hydroxy-4a,6a,8,8-tetramethyl-3,4,4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-tetradecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one
Clinical data
AHFS/Drugs.com	Micromedex Detailed Consumer Information
MedlinePlus	a682272
Pregnancy cat.	?
Legal status	?
Routes	Topical
Identifiers
CAS number	3093-35-4
ATC code	D07AD02
PubChem	= CID 443943 =
ChemSpider	391997
UNII	SI86V6QNEG
ChEMBL	CHEMBL1200845
Chemical data
Formula	C24H32ClFO5
Mol. mass	454.959 g/mol
	SMILES ClCC(=O)[C@]45OC(O[C@@H]5C[C@@H]2[C@@]4(C[C@H](O)[C@]3(F)[C@@]1(/C(=C\C(=O)CC1)CC[C@@H]23)C)C)(C)C;
	InChI InChI=1S/C24H32ClFO5/c1-20(2)30-19-10-16-15-6-5-13-9-14(27)7-8-21(13,3)23(15,26)17(28)11-22(16,4)24(19,31-20)18(29)12-25/h9,15-17,19,28H,5-8,10-12H2,1-4H3/t15-,16-,17-,19+,21-,22-,23-,24+/m0/s1; Key:MUQNGPZZQDCDFT-JNQJZLCISA-N ;
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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2013/04/22 13:41:16」(JST)

For Halog, the capital of the former Indian Princely State, see Dhami.

Halcinonide is a corticosteroid.^[1] It is used topically in the treatment of certain skin conditions.

^ Pujos E, Flament-Waton MM, Paisse O, Grenier-Loustalot MF (January 2005). "Comparison of the analysis of corticosteroids using different techniques". Anal Bioanal Chem 381 (1): 244–54. doi:10.1007/s00216-004-2890-9. ISBN [[Special:BookSources/0021600428909|0021600428909 [[Category:Articles with invalid ISBNs]] [[Category:Articles with invalid ISBNs]]]] Check |isbn= value (help). PMID 15700162.

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Computationally Prediction of Candidate Agents for Preventing Organ Dysfunction After Brain Death.

Liu Q1, Ye Q1.
Annals of transplantation.Ann Transplant.2016 May 12;21:301-10.
BACKGROUND Our aim was to explore the mechanism of post-transplant organ function decrease induced by brain death (BD) and discover a potential candidate drug for improving the survival and organ function after BD. MATERIAL AND METHODS The microarray data developed from the liver tissues after BD we
PMID 27170053

The efficacy of high-intensity, focused ultrasound treatment for non-neoplastic epithelial disorders of the vulva.

Zhou W1, Zhu L2, Zhou H2, Shen K2, Lang J2, Cui Q1, Shi H3.
Cellular and molecular biology (Noisy-le-Grand, France).Cell Mol Biol (Noisy-le-grand).2016 Apr 30;62(4):111-5.
Non-neoplastic epithelial disorders of the vulva (NNEDV) are common types of vulval lesions. Although corticosteroids represent a first-line treatment for NNEDV, concerns exist about the safety associated with long-term topical corticosteroid use. Recently, several clinical trials have identified hi
PMID 27188744

Stratum corneum absorption kinetics of 2 potent topical corticosteroid formulations: a pilot study.

Draelos ZD1.
Cutis.Cutis.2015 Aug;96(2):135-41.
Fluocinonide and halcinonide are class II topical corticosteroids that are indicated for the relief of inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses and generally are applied to affected skin at least twice daily. This pilot study compared the absorption kinetics o
PMID 26367752