WordNet

link together; "can we couple these proposals?" (同)couple on, couple up
two items of the same kind (同)pair, twosome, twain, brace, span, yoke, couplet, distich, duo, duet, dyad, duad
a small indefinite number; "hes coming for a couple of days"
a pair of people who live together; "a married couple from Chicago" (同)mates, match
a pair who associate with one another; "the engaged couple"; "an inseparable twosome" (同)twosome, duo, duet
(physics) something joined by two equal and opposite forces that act along parallel lines
a cellular structure that is postulated to exist in order to mediate between a chemical agent that acts on nervous tissue and the physiological response
connected by a link, as railway cars or trailer trucks (同)joined, linked

PrepTutorEJDIC

(同種類の物が)『2個』《+『of』+『名』》 / 『夫婦』,男女一組 / 《話》(…の)いくらか,少数《+『of』+『名』》 / …'を'『つなぎ合わせる』;(…に)…'を'連結する《+『名』+『to』(『with』)+『名』》 / …'を'(…と)関連づける《+『名』+『with』(『to』)+『名』》 / …'を'結婚させる,〈動物〉'を'つがわせる / 〈動物〉交尾する
=sense organ / 受信装置

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/12/07 17:07:29」(JST)

Guanylate cyclase-coupled receptor or Membrane-bound guanylyl cyclase is a single transmembrane protein.^[1]

They are enzyme-linked receptors:

GC-A (NPR1/GUCY2A) & GC-B (NPR2/GUCY2B): for natriuretic factors such as atrial natriuretic factor (ANF).
GC-C (GUCY2C): for guanylin and uroguanylin.
GC-D (GUCY2D)
GC-E (GUCY2E)
GC-F (GUCY2F)

There is also a human pseudogene for GUCY2GP.

^ George J. Siegel; R. Wayne Albers (2006). Basic neurochemistry: molecular, cellular, and medical aspects. Academic Press. pp. 368–. ISBN 978-0-12-088397-4. Retrieved 16 December 2010.

Guanylate Cyclase-Coupled Receptors at the US National Library of Medicine Medical Subject Headings (MeSH)

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1. 成人における肺高血圧症の治療 treatment of pulmonary hypertension in adults
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5. ヒト免疫不全ウイルス（HIV）関連肺動脈性高血圧症 pulmonary arterial hypertension associated with human immunodeficiency virus

Begg DP1, Steinbrecher KA2, Mul JD3, Chambers AP3, Kohli R2, Haller A3, Cohen MB2, Woods SC3, Seeley RJ3.
Diabetes.Diabetes.2014 Nov;63(11):3798-804. doi: 10.2337/db14-0160. Epub 2014 Jun 4.
Uroguanylin is a gastrointestinal hormone primarily involved in fluid and electrolyte handling. It has recently been reported that prouroguanylin, secreted postprandially, is converted to uroguanylin in the brain and activates the receptor guanylate cyclase-C (GC-C) to reduce food intake and prevent
PMID 24898144

High density and ligand affinity confer ultrasensitive signal detection by a guanylyl cyclase chemoreceptor.

Pichlo M1, Bungert-Plümke S2, Weyand I2, Seifert R1, Bönigk W3, Strünker T1, Kashikar ND4, Goodwin N5, Müller A3, Pelzer P6, Van Q7, Enderlein J7, Klemm C8, Krause E8, Trötschel C9, Poetsch A9, Kremmer E10, Kaupp UB11, Körschen HG, Collienne U.
The Journal of cell biology.J Cell Biol.2014 Aug 18;206(4):541-57. doi: 10.1083/jcb.201402027.
Guanylyl cyclases (GCs), which synthesize the messenger cyclic guanosine 3',5'-monophosphate, control several sensory functions, such as phototransduction, chemosensation, and thermosensation, in many species from worms to mammals. The GC chemoreceptor in sea urchin sperm can decode chemoattractant
PMID 25135936