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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/12/14 09:16:54」(JST)

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  • Comparative efficacy of guanfacine extended release versus atomoxetine for the treatment of attention-deficit/hyperactivity disorder in children and adolescents: applying matching-adjusted indirect comparison methodology.
  • Sikirica V, Findling RL, Signorovitch J, Erder MH, Dammerman R, Hodgkins P, Lu M, Xie J, Wu EQ.SourceGlobal Health Economics and Outcomes Research, Shire Development LLC, 725 Chesterbrook Boulevard, Wayne, PA, 19087, USA,
  • CNS drugs.CNS Drugs.2013 Nov;27(11):943-53. doi: 10.1007/s40263-013-0102-x.
  • BACKGROUND: No head-to-head clinical trials have been published comparing guanfacine extended release (GXR) and atomoxetine (ATX): two nonstimulants approved for the treatment of attention-deficit/hyperactivity disorder (ADHD). However, other study designs or methods could be used to indirectly comp
  • PMID 23975660
  • Guanfacine Extended Release: A Novel Treatment for Attention-Deficit/Hyperactivity Disorder in Children and Adolescents.
  • Faraone SV, McBurnett K, Sallee FR, Steeber J, López FA.SourceDepartment of Psychiatry and Behavioral Sciences, and Medical Genetics Research Center, SUNY Upstate Medical University, Syracuse, New York. Electronic address:
  • Clinical therapeutics.Clin Ther.2013 Oct 16. pii: S0149-2918(13)00952-1. doi: 10.1016/j.clinthera.2013.09.005. [Epub ahead of print]
  • BACKGROUND: Guanfacine extended release (GXR) has reported efficacy for the treatment of attention-deficit/hyperactivity disorder (ADHD) as monotherapy and adjunctive therapy to psychostimulant medications.OBJECTIVE: The objective of this article was to review the efficacy, safety profile, mechanism
  • PMID 24139092
  • Elevated Norepinephrine may be a Unifying Etiological Factor in the Abuse of a Broad Range of Substances: Alcohol, Nicotine, Marijuana, Heroin, Cocaine, and Caffeine.
  • Fitzgerald PJ.SourceDepartment of Psychology, Texas A&M University, College Station, TX.
  • Substance abuse : research and treatment.Subst Abuse.2013 Oct 13;7:171-183.
  • A wide range of commonly abused drugs have effects on the noradrenergic neurotransmitter system, including alterations during acute intoxication and chronic use of these drugs. It is not established, however, that individual differences in noradrenergic signaling, which may be present prior to use o
  • PMID 24151426


  • Central Sympathetic Inhibition Augments Sleep-Related Ultradian Rhythm of Parasympathetic Tone in Patients With Chronic Heart Failure
  • Yamazaki Tsugiyoshi,Asanoi Hidetsugu,Ueno Hiroshi,Yamada Kunihiro,Takagawa Junya,Kameyama Tomoki,Hirai Tadakazu,Ishizaka Shinji,Nozawa Takashi,Inoue Hiroshi
  • Circulation Journal 69(9), 1052-1056, 2005-08-20
  • … To assess autonomic sleep dynamics, the ultradian rhythm was extracted from all-night consecutive high-frequency (HF) components of heart rate variability (HRV) before and after administration of an α2-adrenergic agonist, guanfacine. … Guanfacine reduced blood pressure, heart rate, and plasma norepinephrine concentrations by 7%, 8%, and 34% (p<0.01), respectively. …
  • NAID 110002703838
  • PJ-037 Effects of a Central Sympathoinhibitory Drug, Guanfacine, on Cardiac Metaiodobenzylguanidine Scintigraphy in Patients with Heart Failure(Nuclear Cardiology 3 (I) : PJ7)(Poster Session (Japanese))
  • Igawa Akihiko,Nozawa Takashi,Matsuki Akira,Nakadate Teruo,Yamazaki Tsugiyoshi,Oda Yoshitaka,Igarashi Norio,Katoh Bunichi,Asanoi Hidetsugu,Seto Hikaru,Inoue Hiroshi
  • Circulation journal : official journal of the Japanese Circulation Society 68(Supplement_I), 488, 2004-03-01
  • NAID 110002701644




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