granulocytopenia

出典: meddic

顆粒球減少症顆粒球減少

agranulocytosis


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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2014/08/22 11:32:41」(JST)

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英文文献

  • Adverse effects of propranolol treatment for infantile hemangiomas in China.
  • Jian D1, Chen X, Babajee K, Su J, Li J, Hu X, Xie H, Li J.Author information 1Department of Dermatology, Central South University, XiangYa Hospital , Changsha, Hunan , China.AbstractOBJECTIVES: The β-blocker propranolol was discovered to be highly effective for the treatment of infantile hemangiomas (IHs), since 2008. Although some side effects have been reported earlier, no serious side effects of its use have been reported so far in Asia, especially in China. To determine the safety of this therapy, the side effects were analyzed in 97 infants who used propranolol (2 mg kg(-1)·d(-1)) against hemangioma from 2010 to 2011.
  • The Journal of dermatological treatment.J Dermatolog Treat.2014 Oct;25(5):388-90. doi: 10.3109/09546634.2012.755249. Epub 2013 Feb 24.
  • OBJECTIVES: The β-blocker propranolol was discovered to be highly effective for the treatment of infantile hemangiomas (IHs), since 2008. Although some side effects have been reported earlier, no serious side effects of its use have been reported so far in Asia, especially in China. To determine th
  • PMID 23216314
  • Drug-induced agranulocytosis in the Berlin case-control surveillance study.
  • Huber M1, Andersohn F, Bronder E, Klimpel A, Thomae M, Konzen C, Meyer O, Salama A, Schrezenmeier H, Hildebrandt M, Späth-Schwalbe E, Grüneisen A, Kreutz R, Garbe E.Author information 1Institute of Clinical Pharmacology and Toxicology, Charité - Universitätsmedizin Berlin, Berlin, Germany.AbstractPURPOSE: Drug-induced agranulocytosis (DIAG) is a rare but serious adverse drug reaction. The Berlin Case-Control Surveillance Study (FAKOS) aimed to identify pharmaceuticals with an increased risk for this condition.
  • European journal of clinical pharmacology.Eur J Clin Pharmacol.2014 Mar;70(3):339-45. doi: 10.1007/s00228-013-1618-1. Epub 2013 Dec 3.
  • PURPOSE: Drug-induced agranulocytosis (DIAG) is a rare but serious adverse drug reaction. The Berlin Case-Control Surveillance Study (FAKOS) aimed to identify pharmaceuticals with an increased risk for this condition.METHODS: Adult patients with acute non-chemotherapy-induced agranulocytosis, develo
  • PMID 24297345
  • A single nucleotide polymorphism on the GALNT14 gene as an effective predictor of response to chemotherapy in advanced hepatocellular carcinoma.
  • Yeh CT1, Liang KH, Lin CC, Chang ML, Hsu CL, Hung CF.Author information 1Liver Research Unit, Department of Hepato-Gastroenterology, Chang Gung Memorial Hospital, Taipei, Taiwan; Molecular Medicine Research Center, Chang Gung University, Taoyuan, Taiwan.AbstractPreviously, a pilot genome-wide association study has identified candidate single nucleotide polymorphism predictors for the therapeutic response of 5-fluorouracil, mitoxantrone and cisplatin (FMP) combination chemotherapy in advanced hepatocellular carcinoma (HCC). Here, we conducted a prospective confirmatory study to examine the predictive value of rs9679162 (located on GALNT14 gene) for the therapeutic responses using a split-dose FMP protocol. One hundred and seven advanced HCC patients receiving split-dose FMP therapy were enrolled. All patients were in Barcelona Clinical Liver Cancer Stage C with either main portal vein thrombosis and/or distant metastasis. Of them, 105 (98.1%) were Child-Pugh classification B. GALNT14 genotype was determined before therapy. Of the patients included, 28 were rs9679162 "TT" and 79 were "non-TT" ("GG" + "GT") genotype. The median overall survival, time-to-progression, response rate and disease control rate were ("TT" versus "non-TT") 6.8 versus 3.9 months (p < 0.001), 3.9 versus 2.1 months (p < 0.001), 28.6% versus 10.1% (p = 0.029) and 35.7% versus 15.2% (p = 0.030), respectively. Multivariate analysis indicated that rs9679162 genotype was an independent predictor for overall survival (p = 0.002). Categorical analysis showed that 17 patients with "TT" genotype, tumor size < 10 cm and neutrophils < 74% had a median overall survival of 25.5 months and a therapeutic response rate of 47.1%. In conclusion, this prospective study confirmed that GALN14 genotype (rs9679162) was an effective predictor for therapeutic outcome in advanced HCC patients treated by FMP chemotherapy. Combining GALNT14 genotype and clinical parameters, a subgroup of patients with excellent outcome was identified.
  • International journal of cancer. Journal international du cancer.Int J Cancer.2014 Mar 1;134(5):1214-24. doi: 10.1002/ijc.28439. Epub 2013 Sep 3.
  • Previously, a pilot genome-wide association study has identified candidate single nucleotide polymorphism predictors for the therapeutic response of 5-fluorouracil, mitoxantrone and cisplatin (FMP) combination chemotherapy in advanced hepatocellular carcinoma (HCC). Here, we conducted a prospective
  • PMID 23959947

和文文献

  • 高齢者頭頸部癌患者に対する化学放射線同時併用療法の検討
  • 下鑪 裕子,嶋根 俊和,中村 泰介 [他],川口 顕一朗,渡邉 彩,藤居 直和,池田 賢一郎,五味渕 寛,小林 斉
  • 耳鼻咽喉科臨床 107(9), 721-728, 2014
  • … In elderly patients treated with concurrent chemoradiation therapy (CCRT), complications after initiation of therapy, such as delirium, as well as adverse events such as radiation mucositis and granulocytopenia, are considered to affect the subsequent therapy completion rate and treatment effect and may also lead to a poor performance status (PS). …
  • NAID 130004685615
  • チアマゾール投与中に薬剤熱を認めその後に顆粒球減少をきたした多腺性自己免疫症候群3型の1例
  • 戸塚 大輔,入村 泉,大屋 純子 [他],花井 豪,柳沢 慶香,市原 淳弘,堀内 喜代美,岡本 高宏,山本 智子,西川 俊郎,内潟 安子
  • 東京女子医科大学雑誌 82(6), 384-387, 2012-12-25
  • 抗甲状腺薬であるチアマゾール(MMI)は,無顆粒球症をはじめとして多彩な副作用が知られている.無顆粒球症により感染が引き起こされ,その後あるいは同時に発熱を認めることが一般的であるが,我々はMMI内服中に薬剤熱と思われる発熱をきたし,その後に顆粒球減少を認めた症例を経験したので報告する. 症例は35歳男性.2008年バセドウ病と診断されMMI内服開始されるも,2年後に自己中止した.1年後,体重減少 …
  • NAID 110009557527
  • Nafcillin-Induced Bullous Skin Eruption with Granulocytopenia in a Patient with End-Stage Renal Disease
  • Chang Mine-Ok,Sil Koh Eun,Ju Kim Min,Joon Shin Seok,Whee Park Cheol,Sik Chang Yoon,Chung Sungjin
  • Internal Medicine 51(3), 287-289, 2012
  • Nafcillin is an antibiotic used for infections due to penicillin-resistant Staphylococcus aureus. In general, the adverse reactions to nafcillin have not been frequent and serious. We report here a ne …
  • NAID 130002061973

関連リンク

granulocytopenia [gran″u-lo-si″to-pe´ne-ah] a reduction in the number of granular leukocytes in the blood that is less severe than agranulocytosis; called also granulopenia. gran·u·lo·cy·to·pe·ni·a (gran'yū-lō-sī'tō-pē'nē-ă), Fewer than the ...
Granulocytopenia definition at Dictionary.com, a free online dictionary with pronunciation, synonyms and translation. Look it up now! Thesaurus Translate Puzzles & Games Word of the Day Blog Slideshows Apps by Dictionary ...

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★リンクテーブル★
先読みagranulocytosis
リンク元好中球減少症」「顆粒球減少症」「顆粒球減少
拡張検索drug-induced granulocytopenia

agranulocytosis」

  [★] 無顆粒球症

WordNet   license wordnet

「an acute blood disorder (often caused by radiation or drug therapy) characterized by severe reduction in granulocytes」
agranulosis, granulocytopenia


好中球減少症」

  [★]

neutropenia
好中球減少顆粒球減少症 granulocytopenia
好中球




顆粒球減少症」

  [★]

granulocytopenia
無顆粒球症 agranulocytosis顆粒球減少好中球減少症



顆粒球減少」

  [★]

granulocytopenia
顆粒球減少症


drug-induced granulocytopenia」

  [★] 薬剤性顆粒球減少症




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