gonadotropin-releasing hormone

出典: meddic

性腺刺激ホルモン放出ホルモン

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2016/07/21 23:03:59」(JST)

wiki en

[Wiki en表示]

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2016/10/08 19:57:16」(JST)

wiki en

[Wiki en表示]

UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

英文文献

  • Androgen-deprivation Therapy in Treatment of Prostate Cancer and Risk of Myocardial Infarction and Stroke: A Nationwide Danish Population-based Cohort Study.
  • Jespersen CG1, Nørgaard M2, Borre M3.Author information 1Department of Urology, Aarhus University Hospital, Aarhus, Denmark; Institute of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark. Electronic address: christina.gade@ki.au.dk.2Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark.3Department of Urology, Aarhus University Hospital, Aarhus, Denmark.AbstractBACKGROUND: Androgen-deprivation therapy (ADT) has been suggested to increase the risk for cardiovascular diseases, including myocardial infarction (MI) and stroke, but data are inconsistent.
  • European urology.Eur Urol.2014 Apr;65(4):704-9. doi: 10.1016/j.eururo.2013.02.002. Epub 2013 Feb 12.
  • BACKGROUND: Androgen-deprivation therapy (ADT) has been suggested to increase the risk for cardiovascular diseases, including myocardial infarction (MI) and stroke, but data are inconsistent.OBJECTIVES: To investigate the association between ADT and risk for MI and stroke in Danish men with prostate
  • PMID 23433805
  • Fox tales: Regulation of gonadotropin gene expression by forkhead transcription factors.
  • Thackray VG.Author information Department of Reproductive Medicine and Center for Reproductive Science and Medicine, University of California, San Diego, La Jolla, CA 92093, United States. Electronic address: vthackray@ucsd.edu.AbstractLuteinizing hormone (LH) and follicle-stimulating hormone (FSH) are produced by pituitary gonadotrope cells and are required for steroidogenesis, the maturation of ovarian follicles, ovulation, and spermatogenesis. Synthesis of LH and FSH is tightly regulated by a complex network of signaling pathways activated by hormones including gonadotropin-releasing hormone, activin and sex steroids. Members of the forkhead box (FOX) transcription factor family have been shown to act as important regulators of development, homeostasis and reproduction. In this review, we focus on the role of four specific FOX factors (FOXD1, FOXL2, FOXO1 and FOXP3) in gonadotropin hormone production and discuss our current understanding of the molecular function of these factors derived from studies in mouse genetic and cell culture models.
  • Molecular and cellular endocrinology.Mol Cell Endocrinol.2014 Mar 25;385(1-2):62-70. doi: 10.1016/j.mce.2013.09.034. Epub 2013 Oct 4.
  • Luteinizing hormone (LH) and follicle-stimulating hormone (FSH) are produced by pituitary gonadotrope cells and are required for steroidogenesis, the maturation of ovarian follicles, ovulation, and spermatogenesis. Synthesis of LH and FSH is tightly regulated by a complex network of signaling pathwa
  • PMID 24099863
  • PACAP modulates GnRH signaling in gonadotropes.
  • Halvorson LM.Author information Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390-9032, United States. Electronic address: lisa.halvorson@utsouthwestern.edu.AbstractHypothalamic gonadotropin-releasing hormone is known to be critical for normal gonadotropin biosynthesis and secretion by the gonadotrope cells of the anterior pituitary gland. Additional regulation is provided by gonadal steroid feedback as well as by intrapituitary factors, such as activin and follistatin. Less well-appreciated is the role of pituitary adenylate-cyclase activating polypeptide (PACAP) as both a hypothalamic-pituitary releasing factor as well as an autocrine-paracrine factor within the pituitary. PACAP regulates gonadotropin expression alone and through modulation of GnRH responsiveness achieved by increases in GnRH receptor expression and interactions at the level of intracellular signaling pathways. In addition to direct effects on the gonadotrope, PACAP stimulates follistatin secretion by the folliculostellate cells and thereby contributes to differential expression of the gonadotropin subunits. Conversely, GnRH augments the ability of PACAP to regulate gonadotrope function by increasing pituitary PACAP and PACAP receptor expression. This review will summarize the current understanding of the mechanisms by which PACAP modulates gonadotrope function, with a focus on interactions with GnRH.
  • Molecular and cellular endocrinology.Mol Cell Endocrinol.2014 Mar 25;385(1-2):45-55. doi: 10.1016/j.mce.2013.09.029. Epub 2013 Oct 2.
  • Hypothalamic gonadotropin-releasing hormone is known to be critical for normal gonadotropin biosynthesis and secretion by the gonadotrope cells of the anterior pituitary gland. Additional regulation is provided by gonadal steroid feedback as well as by intrapituitary factors, such as activin and fol
  • PMID 24095645

和文文献

  • 16歳の非交通性副角子宮を伴う単角子宮に対し腹腔鏡下手術を行った1例
  • 五十嵐 秀樹,高橋 俊文,堤 誠司,網田 光善,高橋 一広
  • 山形大学紀要. 医学 : 山形医学 33(1), 47-53, 2015-02-15
  • 非交通性副角子宮を伴う単角子宮はミュラー管発生異常による希な先天性子宮奇形である。典型的な 症状は子宮留血腫と子宮内膜症による進行性の下腹部痛と月経困難症である。また、高頻度に腎尿路系 の奇形を伴う。我々は重度の下腹部痛と月経困難症を呈した非交通性副角子宮を有する単角子宮の16歳 の患者に対し、腹腔鏡による診断と加療を行った。診断的腹腔鏡検査と子宮鏡検査を施行し、非交通性 副角子宮を伴う単角子宮と …
  • NAID 110009889048
  • 性腺刺激ホルモン放出ホルモン及び卵胞刺激ホルモン処理が黒毛和種雌牛の生体内卵子吸引に及ぼす影響
  • 谷口 俊仁,高田 広達,樽本 英幸
  • 和歌山県農林水産試験研究機関研究報告 = Bulletin of the Wakayama Prefectural Experiment Stations of Agriculture, Forestry and Fisheries (3), 125-130, 2015
  • NAID 40020400011
  • 4-Nitro-3-phenylphenol has both androgenic and anti-androgenic-like effects in rats
  • , , , ,
  • Journal of Reproduction and Development 61(2), 134-137, 2015
  • … To investigate the effect of endocrine disruption of 4-nitro-3-phenylphenol (PNMPP) on immature male Wistar-Imamichi rats, the rat pituitary was exposed to PNMPP (10–5–10–9 M) for 24 h with or without gonadotropin-releasing hormone (GnRH) in experiment I. … In addition, the Leydig cells (10–5–10–9 M) were exposed to PNMPP for 24 h with or without human chronic gonadotropin (hCG) in experiment II. …
  • NAID 130005064912

関連リンク

Wikipedia(ウィキペディア)記事検索 > [ Gonadotropin-releasing hormone ] の検索結果
GnRH antagonist protocols: Gonadotropin-releasing hormone antagonists result in internalizetion and subcellular translocation of the GnRH receptor to the cell nucleus, and down-regulation of messenger ribonucleic acid (mRNA ...

関連画像


押しても画像が表示されない場合はサーバが混雑しています。2週間ほどあけて、再度押下してください。


★リンクテーブル★
リンク元視床下部ホルモン」「性腺刺激ホルモン放出ホルモン」「gonadorelin」「生殖腺刺激ホルモン放出ホルモン」「性腺刺激放出ホルモン
拡張検索gonadotropin-releasing hormone analog」「gonadotropin-releasing hormoneantagonist」「gonadotropin-releasing hormoneagonist」「gonadotropin-releasing hormone derivative
関連記事hormone」「gonadotropin

視床下部ホルモン」

  [★]

hypothalamic hormone
視床下部

一覧 (2007後期生理学授業プリント)

成長ホルモン放出ホルモン somatotrpin-releasing hormone SRH GH分泌↑
ソマトスタチン growth hormone-inhibiting factor / somatostatin GIF GH分泌↓
甲状腺刺激ホルモン放出ホルモン thyroid-stimulating hormone-relaing hormone TRH TSH分泌↑
副腎皮質刺激ホルモン放出ホルモン corticotropin-releasing hormone CRH ACTH分泌↑
ゴナドトロピン放出ホルモン gonadotropin-releasing hormone GnRH FSH分泌↑、LH分泌↑
プロラクチン放出因子 prolactin-releasing factor PRF prolactin分泌↑
プロラクチン抑制因子 prolactin-inhibiting factor PIF prolactin分泌↓

構造

性腺刺激ホルモン放出ホルモン」

  [★]

gonadotropin-releasing hormone gonadotropin releasing hormone GnRH
ゴナドトロピン放出ホルモンLH-releasing hormoneLH-RHLHRHluteinizing hormone-releasing hormone
ホルモン
gonadorelin
  • Gonadotropin-Releasing Hormone
  • pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2 (MW = 1182.39)



gonadorelin」

  [★]

ゴナドレリン

Gn-RHGnRHgonadorelin diacetategonadorelin hydrochloridegonadotropin-releasing hormoneLH-releasing hormoneLH-RHLHRHluteinizing hormone-releasing hormone
Factrel, Lutrepulse


生殖腺刺激ホルモン放出ホルモン」

  [★]

gonadotropin-releasing hormoneGnRH
黄体形成ホルモン放出ホルモンゴナドレリン性腺刺激ホルモン放出ホルモン塩酸ゴナドレリン


性腺刺激放出ホルモン」

  [★]

gonadotropin-releasing hormone


gonadotropin-releasing hormone analog」

  [★] 性腺刺激ホルモン放出ホルモンアナログ化合物, GnRHa


gonadotropin-releasing hormoneantagonist」

  [★] 性腺刺激ホルモン放出ホルモン拮抗物


gonadotropin-releasing hormoneagonist」

  [★] 性腺刺激ホルモン放出ホルモン誘導体

gonadotropin-releasing hormone derivative」

  [★] 性腺刺激ホルモン放出ホルモン誘導体

hormone」

  [★] ホルモン

WordNet   license wordnet

「the secretion of an endocrine gland that is transmitted by the blood to the tissue on which it has a specific effect」
endocrine, internal secretion

PrepTutorEJDIC   license prepejdic

「ホルモン」


gonadotropin」

  [★] 性腺刺激ホルモン

WordNet   license wordnet

「hormone secreted by the anterior pituitary gland and placenta; stimulates the gonads and controls reproductive activity」
gonadotrophin, gonadotropic hormone, gonadotrophic hormone




★コメント★

[メモ入力エリア]
※コメント5000文字まで
ニックネーム:
コメント:




表示
個人用ツール


  meddic.jp

リンク
連絡