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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2014/09/14 06:40:56」(JST)
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- 1. 原発性無月経の原因 causes of primary amenorrhea
- 2. 性腺刺激ホルモン放出ホルモン単独欠乏症（特発性低ゴナドトロピン性性腺機能低下症） isolated gonadotropin releasing hormone deficiency idiopathic hypogonadotropic hypogonadism
English Journal
- Naturally occurring genetic mutations in the 5'-upstream regulatory region of bovine FSHB generate a novel cis-regulatory element that affects its expression.
- Dai L1, Xu Y1, Yu W1, Liu S1, Gao Y1, Zhang L1, Yuan B1, Chen J1, Ma T1, Zhang J1.
- Animal genetics.Anim Genet.2015 Dec;46(6):693-6. doi: 10.1111/age.12348. Epub 2015 Oct 18.
- We previously reported that numerous naturally occurring genetic mutations in the 5'-upstream regulatory region (5'-URR) of the bovine follicle-stimulating hormone beta-subunit gene (FSHB) were associated with reduced serum follicle-stimulating hormone (FSH) levels, poor-quality semen and low fertil
- PMID 26478576
- Correlative Light and Scanning Electron Microscopy for Observing the Three-Dimensional Ultrastructure of Membranous Cell Organelles in Relation to Their Molecular Components.
- Koga D1, Kusumi S2, Bochimoto H2, Watanabe T2, Ushiki T2.
- The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.J Histochem Cytochem.2015 Dec;63(12):968-79. doi: 10.1369/0022155415609099. Epub 2015 Sep 15.
- Although the osmium maceration method has been used to observe three-dimensional (3D) structures of membranous cell organelles with scanning electron microscopy (SEM), the use of osmium tetroxide for membrane fixation and the removal of cytosolic soluble proteins largely impairs the antigenicity of
- PMID 26374827
- Aggressive tumor growth and clinical evolution in a patient with X-linked acro-gigantism syndrome.
- Naves LA1, Daly AF2, Dias LA3, Yuan B4, Zakir JC5, Barra GB6, Palmeira L2, Villa C2,7, Trivellin G8, Júnior AJ5, Neto FF9, Liu P4, Pellegata NS10, Stratakis CA8, Lupski JR4,11,12,13, Beckers A14.
- Endocrine.Endocrine.2015 Nov 25. [Epub ahead of print]
- X-linked acro-gigantism (X-LAG) syndrome is a newly described disease caused by microduplications on chromosome Xq26.3 leading to copy number gain of GPR101. We describe the clinical progress of a sporadic male X-LAG syndrome patient with an Xq26.3 microduplication, highlighting the aggressive natur
- PMID 26607152
Japanese Journal
- Ubiquitin C-Terminal Hydrolase L1 Is Expressed in Mouse Pituitary Gonadotropes In Vivo and Gonadotrope Cell Lines In Vitro
- XU Yang,HIDESHIMA Makoto,ISHII Yoshiyuki [他]
- Experimental animals 63(2), 247-256, 2014-04
- NAID 40020045309
- Ubiquitin C-Terminal Hydrolase L1 Is Expressed in Mouse Pituitary Gonadotropes In Vivo and Gonadotrope Cell Lines In Vitro
- Xu Yang,Hideshima Makoto,Ishii Yoshiyuki,Yoshikawa Yasuhiro,Kyuwa Shigeru
- Experimental Animals 63(2), 247-256, 2014
- The ubiquitin-proteasome system (UPS) plays a fundamental role in regulating various biological activities. Ubiquitin C-terminal hydrolase L1 (UCH-L1) is a deubiquitinating enzyme, b …
- NAID 130003391626
- Signaling Responses to Pulsatile Gonadotropin-releasing Hormone in L beta T2 Gonadotrope Cells
- Tsutsumi Rie,Mistry Devendra,Webster Nicholas J. G.
- JOURNAL OF BIOLOGICAL CHEMISTRY 285(26), 20262-20272, 2010
- NAID 80021112767
Related Links
- The latest from Gonadotrope (@gonadotrope). Vivent l'amour, l'humour et le sport! ... Gonadotrope @ gonadotrope · Mar 24 Il ne veut vraiment pas partir. Vdm http:// rmcsport.bfmtv.com/info/591493/an igo-inenvisageable-lacher ...
- Gonadotrope definition, a gonadotropic substance. See more. Added to Favorites Dictionary Thesaurus Word Dynamo Quotes Reference Translator Spanish Log In Sign Up Premium gonadotrope gonadotrope / / [goh-nad -uh-trohp] ...
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★リンクテーブル★
| リンク元 | 「下垂体前葉ホルモン」「ゴナドトロピン産生細胞」「性腺刺激ホルモン産生細胞」 |
「下垂体前葉ホルモン」
分泌されるホルモン
- 単純ペプチドホルモン
- 糖タンパク質ホルモン
GOO. chapter 55
| 名称 | 構造 | 分泌細胞 | 下垂体前葉細胞 全細胞に対する 産生細胞の割合 |
染色性 | サブユニット | 残基数 (aa.) |
分子量 (kDa) |
その他 | ||
| 成長ホルモン | GH | ペプチド | somatotroph | 40-50% | 好酸性 | 1 | 191 | 22 | ||
| プロラクチン | PRL | mammotroph | 10-25% | 好酸性 | 1 | 199 | 23 | |||
| 副腎皮質刺激ホルモン | ACTH | corticotroph | 0.1 | 好塩基性 | 嫌色素性 | 1 | 39 | 4.5 | POMC由来 | |
| 甲状腺刺激ホルモン | TSH | 糖タンパク | thyrotroph | 0.05 | 好塩基性 | 2 | α: 92, β:118 | 28 | αサブユニットは共通 | |
| 卵胞刺激ホルモン | FSH | gonadotroph | 10-15% | 好塩基性 | 2 | α: 92, β:111 | 32.6 | |||
| 黄体形成ホルモン | LH | 好塩基性 | 2 | α: 92, β:121 | 29.4 | |||||
HIM.2196
| Table 333-1 Anterior Pituitary Hormone Expression and Regulation | |||||
| Cell | corticotrope | somatotrope | lactotrope | thyrotrope | gonadotrope |
| Tissue-specific transcription factor | T-Pit | Prop-1, Pit-1 | Prop-1, Pit-1 | Prop-1, Pit-1, TEF | SF-1, DAX-1 |
| Fetal appearance | 6 weeks | 8 weeks | 12 weeks | 12 weeks | 12 weeks |
| Hormone | POMC | GH | PRL | TSH | FSH LH |
| Chromosomal locus | 2p | 17q | 6 | －6q; －1p | －11p; －19q |
| Protein | ポリペプチド | 糖タンパク | |||
| Amino acids | 266 (ACTH 1–39) | 191 | 199 | 211 | 210 204 |
| Stimulators | CRH, AVP, gp-130 cytokines | GHRH, ghrelin, bromocriptine(1) | estrogen, TRH, VIP | TRH | GnRH, activins, estrogen |
| Inhibitors | glucocorticoids | somatostatin, IGF-I | dopamine | T3, T4, dopamine, somatostatin, glucocorticoids | sex steroids, inhibin |
| Target gland | adrenal | liver, other tissues | breast, other tissues | thyroid | ovary, testis |
| Trophic effect | steroid production | IGF-I production, growth induction, insulin antagonism | milk production | T4 synthesis and secretion | sex steroid production, follicle growth, germ cell maturation |
- (1):QB.D-253