グリシントランスポーター、グリシン輸送体

関: glycine plasma membrane transport protein、glycine transporter 1、glycine transporter 2

WordNet

move something or somebody around; usually over long distances
an exchange of molecules (and their kinetic energy and momentum) across the boundary between adjacent layers of a fluid or across cell membranes
move while supporting, either in a vehicle or in ones hands or on ones body; "You must carry your camping gear"; "carry the suitcases to the car"; "This train is carrying nuclear waste"; "These pipes carry waste water into the river" (同)carry
transport commercially (同)send, ship
a long truck for carrying motor vehicles (同)car transporter
a crane for moving material with dispatch as in loading and unloading ships
the simplest amino acid found in proteins and the principal amino acid in sugar cane
genus of Asiatic erect or sprawling herbs: soya bean (同)genus Glycine

PrepTutorEJDIC

(ある場所からある場所へ)…‘を'『輸送する』,運搬する《+名+from+名+to+名》 / 《文》《受動態で》(…で)…‘を'夢中にする,有頂天にする《+名+with+名》 / 〈罪人〉‘を'流刑にする / 〈U〉輸送,運送,輸送(交通)機関(transportation) / 〈C〉(軍隊や軍需品を運ぶ)輸送船,輸送機
自動車運搬用大型トラック

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/10/21 05:51:48」(JST)

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[Wiki en表示]

Glycine transporters (GlyTs) are plasmalemmal neurotransmitter transporters. They serve to terminate the signaling of glycine by mediating its reuptake from the synaptic cleft into back presynaptic neurons. There are two glycine transporters: glycine transporter 1 (GlyT1) and glycine transporter 2 (GlyT2).^[1]

References

^ Harvey RJ, Yee BK (November 2013). "Glycine transporters as novel therapeutic targets in schizophrenia, alcohol dependence and pain". Nat Rev Drug Discov. 12 (11): 866–85. doi:10.1038/nrd3893. PMID 24172334.

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1. 新生児における筋緊張低下を引き起こす末梢神経および筋肉の障害に関する概要 overview of peripheral nerve and muscle disorders causing hypotonia in the newborn
2. 鉄のバランス調節 regulation of iron balance
3. 先天性および後天性鉄芽球性貧血の原因 causes of congenital and acquired sideroblastic anemias
4. シスプラチン腎障害 cisplatin nephrotoxicity
5. 小児における運動過多な運動障害 hyperkinetic movement disorders in children

English Journal

Isolation and characterisation of transport-defective substrate-binding mutants of the tetracycline antiporter TetA(B).

Wright DJ1, Tate CG2.
Biochimica et biophysica acta.Biochim Biophys Acta.2015 Oct;1848(10 Pt A):2261-70. doi: 10.1016/j.bbamem.2015.06.026. Epub 2015 Jul 2.
The tetracycline antiporter TetA(B) is a member of the Major Facilitator Superfamily which confers tetracycline resistance to cells by coupling the efflux of tetracycline to the influx of protons down their chemical potential gradient. Although it is a medically important transporter, its structure
PMID 26143388

Na(+)-dependent and Na(+)-independent betaine transport across the apical membrane of rat renal epithelium.

Cano M1, Calonge ML2, Ilundáin AA1.
Biochimica et biophysica acta.Biochim Biophys Acta.2015 Oct;1848(10 Pt A):2172-9. doi: 10.1016/j.bbamem.2015.05.020. Epub 2015 May 29.
The low renal excretion of betaine indicates that the kidney efficiently reabsorbs the betaine filtered by the glomeruli but the mechanisms involved in such a process have been scarcely investigated. We have detected concentrative and non-concentrative betaine transport activity in brush-border memb
PMID 26028423

Genetic ablation of VIAAT in glycinergic neurons causes a severe respiratory phenotype and perinatal death.

Rahman J1, Besser S, Schnell C, Eulenburg V, Hirrlinger J, Wojcik SM, Hülsmann S.
Brain structure & function.Brain Struct Funct.2015 Sep;220(5):2835-49. doi: 10.1007/s00429-014-0829-2. Epub 2014 Jul 16.
Both glycinergic and GABAergic neurons require the vesicular inhibitory amino acid transporter (VIAAT) for synaptic vesicle filling. Presynaptic GABA concentrations are determined by the GABA-synthesizing enzymes glutamate decarboxylase (GAD)65 and GAD67, whereas the presynaptic glycine content depe
PMID 25027639

Japanese Journal

Identification of 1-Methyl-N-(propan-2-yl)-N-({2-[4-(trifluoromethoxy)phenyl]pyridin-4-yl}methyl)-1H-imidazole-4-carboxamide as a Potent and Orally Available Glycine Transporter 1 Inhibitor

ＣＨＥＭＩＣＡＬ　＆　ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ　ＢＵＬＬＥＴＩＮ 64(11), 1630-1640, 2016
NAID 130005268088

Discovery of 3-Chloro-N-{(S)-[3-(1-ethyl-1H-pyrazol-4-yl)phenyl][(2S)-piperidine-2-yl]methyl}-4-(trifluoromethyl)pyridine-2-carboxamide as a Potent Glycine Transporter 1 Inhibitor

ＣＨＥＭＩＣＡＬ　＆　ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ　ＢＵＬＬＥＴＩＮ 64(9), 1321-1337, 2016
NAID 130005261563

A Highly Selective Inhibitor of Glycine Transporter-1 Elevates the Threshold for Maximal Electroshock-Induced Tonic Seizure in Mice

Biological and Pharmaceutical Bulletin 39(2), 174-180, 2016
NAID 130005122358

「glycine plasma membrane transport protein」

　　[★]

細胞膜グリシントランスポーター、細胞膜グリシン輸送体、グリシントランスポーター、グリシン輸送体

関: glycine transporter、glycine transporter 1、glycine transporter 2

「グリシントランスポーター」

　　[★]

英: glycine transporter, GLYT
関: 細胞膜グリシントランスポーター、細胞膜グリシン輸送体、グリシン輸送体、グリシン輸送体1、グリシン輸送体2

「グリシン輸送体」

　　[★]

英: glycine transporter
関: 細胞膜グリシントランスポーター、細胞膜グリシン輸送体、グリシントランスポーター

「GLYT」

　　[★] グリシントランスポーター glycine transporter

「glycine transporter 1」

　　[★]

グリシン輸送体1、グリシントランスポーター1

関: glycine plasma membrane transport protein、glycine transporter、glycine transporter 2、GlyT1

「glycine transporter 2」

　　[★]

グリシン輸送体2、グリシントランスポーター2

関: glycine plasma membrane transport protein、glycine transporter、glycine transporter 1、GlyT2

「transport」

　　[★]

n.

輸送、運搬

v.

輸送する、運搬する、運ぶ

関: bring、carriage、carry、convey、delivery、ship、traffic、trafficking、transportation

「transporter」

　　[★] トランスポーター

関: translocator、transport protein、transporter protein

[pmid24172334-1] Harvey RJ, Yee BK (November 2013). "Glycine transporters as novel therapeutic targets in schizophrenia, alcohol dependence and pain". Nat Rev Drug Discov. 12 (11): 866–85. doi:10.1038/nrd3893. PMID 24172334.

v t e Membrane transport protein: neurotransmitter transporters (TC 2.A.1.2)

Vesicular	Vesicular monoamine VMAT1 VMAT2 Vesicular acetylcholine Vesicular glutamate Vesicular GABA

Other	Monoamine DAT NET SERT PMAT Excitatory amino-acid transporter GABA transporter

リンク元	「glycine plasma membrane transport protein」「グリシントランスポーター」「グリシン輸送体」「GLYT」
拡張検索	「glycine transporter 1」「glycine transporter 2」
関連記事	「transport」「transporter」

匿名

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案内

案内

glycine transporter