WordNet

a salt of phosphoric acid (同)orthophosphate, inorganic_phosphate
carbonated drink with fruit syrup and a little phosphoric acid
a monosaccharide sugar that has several forms; an important source of physiological energy

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〈U〉リン酸塩 / 《複数形で》リン酸肥料
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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2012/12/27 18:10:34」(JST)

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Glucose 1-phosphate (also called cori ester) is a glucose molecule with a phosphate group on the 1'-carbon. It can exist in either the α- or β-anomeric form.

Reactions of α-glucose 1-phosphate

Catabolic

In glycogenolysis, it is the direct product of the reaction in which glycogen phosphorylase cleaves off a molecule of glucose from a greater glycogen structure.

To be utilized in cellular catabolism it must first be converted to glucose 6-phosphate by the enzyme phosphoglucomutase. One reason that cells form glucose 1-phosphate instead of glucose during glycogen breakdown is that the very polar phosphorylated glucose cannot leave the cell membrane and so is marked for intracellular catabolism.

Anabolic

In glycogenesis, free glucose 1-phosphate can also react with UTP to form UDP-glucose, by using the enzyme UDP-glucose pyrophosphorylase. It can then return to the greater glycogen structure via glycogen synthase.

β-Glucose 1-phosphate

β-Glucose 1-phosphate is found in some microbes. It is produced by inverting α-glucan phosphorylases including maltose phosphorylase, kojibiose phosphorylase and trehalose phosphorylase and is then converted into glucose 6-phosphate by β-phosphoglucomutase.

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1. グルコース-6-リン酸脱水素酵素欠損症の診断および治療 diagnosis and treatment of glucose 6 phosphate dehydrogenase deficiency
2. Regulation of calcium and phosphate balance
3. グルコース-6-リン酸脱水素酵素欠損症の臨床症状 clinical manifestations of glucose 6 phosphate dehydrogenase deficiency
4. グルコース-6-リン酸脱水素酵素欠損症の遺伝学および病態生理 genetics and pathophysiology of glucose 6 phosphate dehydrogenase deficiency
5. 免疫不全症を引き起こすミエロペルオキシダーゼ欠損症および酵素白血球欠損症 myeloperoxidase deficiency and other enzymatic wbc defects causing immunodeficiency

English Journal

2-Oxo-1,2-dihydropyridinyl-3-yl amide-based GPa inhibitors: Design, synthesis and structure-activity relationship study.

Loughlin WA1, Jenkins ID2, Karis ND2, Schweiker SS2, Healy PC3.
European journal of medicinal chemistry.Eur J Med Chem.2016 Mar 23;111:1-14. doi: 10.1016/j.ejmech.2016.01.031. Epub 2016 Jan 23.
Glycogen phosphorylase (GP), which plays a crucial role in the conversion of glycogen to glucose-1-phosphate, is a target for therapeutic intervention in diabetes. In this study, we report the design and synthesis of 29 new derivatives of 2-oxo-1,2-dihydro pyridin-3-yl amides, as potential inhibitor
PMID 26851835

Induced structural disorder as a molecular mechanism for enzyme dysfunction in phosphoglucomutase 1 deficiency.

Stiers KM1, Kain BN1, Graham AC1, Beamer LJ2.
Journal of molecular biology.J Mol Biol.2016 Mar 10. pii: S0022-2836(16)00162-5. doi: 10.1016/j.jmb.2016.02.032. [Epub ahead of print]
Human phosphoglucomutase 1 (PGM1) plays a central role in cellular glucose homeostasis, mediating the switch between glycolysis and gluconeogenesis through the conversion of glucose 1-phosphate and glucose 6-phosphate. Recent clinical studies have identified mutations in this enzyme as the cause of
PMID 26972339

One-Pot Biosynthesis of High-Concentration α-Glucose 1-Phosphate from Starch by Sequential Addition of Three Hyperthermophilic Enzymes.

Zhou W1, You C2, Ma H1, Ma Y1, Zhang YH1,2,3.
Journal of agricultural and food chemistry.J Agric Food Chem.2016 Mar 2;64(8):1777-83. doi: 10.1021/acs.jafc.5b05648. Epub 2016 Feb 17.
α-Glucose 1-phosphate (G1P) is synthesized from 5% (w/v) corn starch and 1 M phosphate mediated by α-glucan phosphorylase (αGP) from the thermophilic bacterium Thermotoga maritima at pH 7.2 and 70 °C. To increase G1P yield from corn starch containing branched amylopectin, a hyper-thermostable is
PMID 26832825

Japanese Journal

Production and application of a rare disaccharide using sucrose phosphorylase from Leuconostoc mesenteroides(ENZYMOLOGY, PROTEIN ENGINEERING, AND ENZYME TECHNOLOGY)

Journal of bioscience and bioengineering 119(6), 652-656, 2015-06
NAID 110009970753

Construction of an efficient Escherichia coli whole-cell biocatalyst for D-mannitol production(MICROBIAL PHYSIOLOGY AND BIOTECHNOLOGY)

Journal of bioscience and bioengineering 118(6), 628-631, 2014-12
NAID 110009900845

α-D-グルコース1-リン酸アナログ基質を用いたグルカンホスホリラーゼによる酵素的グリコシル化反応(応用糖質科学シンポジウム)

応用糖質科学 : 日本応用糖質科学会誌 4(2), 160-166, 2014-05-20
NAID 110009823326

「グルコース6-リン酸」

Glucose 1-phosphate
	; Anionic form of α-D-glucose 1-phosphate
	; Neutral form of α-D-glucose 1-phosphate
	IUPAC name Glucose 1-phosphate
	Other names Cori ester
Identifiers
CAS number	59-56-3
PubChem	65533
ChemSpider	388311
MeSH	glucose-1-phosphate
ChEBI	CHEBI:16077
Jmol-3D images	Image 1
	SMILES O=P(O)(OC1O[C@@H]([C@@H](O)[C@H](O)[C@H]1O)CO)O ;
	InChI InChI=1S/C6H13O9P/c7-1-2-3(8)4(9)5(10)6(14-2)15-16(11,12)13/h2-10H,1H2,(H2,11,12,13)/t2-,3-,4+,5-,6?/m1/s1 ; Key: HXXFSFRBOHSIMQ-GASJEMHNSA-N InChI=1/C6H13O9P/c7-1-2-3(8)4(9)5(10)6(14-2)15-16(11,12)13/h2-10H,1H2,(H2,11,12,13)/t2-,3-,4+,5-,6?/m1/s1; Key: HXXFSFRBOHSIMQ-GASJEMHNBR ;
Properties
Molecular formula	C6H13O9P
Molar mass	260.14 g mol−1
	(verify) (what is: /?); Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
	Infobox references

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英: glucose 6-phosphate, G6P, G-6-P
同: グルコース-6-リン酸 glucose-6-phosphate
関: グルコース1-リン酸、グルコース、解糖系、糖新生