glucocorticoid myopathy

糖質コルチコイドミオパチー

WordNet

1. a steroid hormone that is produced by the adrenal cortex of animals; affects functioning of gonads and has anti-inflammatory activity
2. any pathology of the muscles that is not attributable to nerve dysfunction

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• 1. ステロイド誘導性ミオパチー glucocorticoid induced myopathy
• 2. 関節リウマチの神経学的症状 neurologic manifestations of rheumatoid arthritis
• 3. 薬物誘導性ミオパシー drug induced myopathies
• 4. ステロイドの全身投与の主な副作用 major side effects of systemic glucocorticoids
• 5. 成人における皮膚筋炎および多発性筋炎の初期治療 initial treatment of dermatomyositis and polymyositis in adults

English Journal

• Role of Myofibrillar Protein Catabolism in Development of Glucocorticoid Myopathy: Aging and Functional Activity Aspects.

• Seene T1, Kaasik P2.
• Metabolites.Metabolites.2016 May 13;6(2). pii: E15. doi: 10.3390/metabo6020015.
• Muscle weakness in corticosteroid myopathy is mainly the result of the destruction and atrophy of the myofibrillar compartment of fast-twitch muscle fibers. Decrease of titin and myosin, and the ratio of nebulin and MyHC in myopathic muscle, shows that these changes of contractile and elastic protei
• PMID 27187487

• CLINICAL PROBLEM-SOLVING. Eye of the Beholder.

• MacFarlane L1, Osman N1, Ritter S1, Miller AL1, Loscalzo J1.
• The New England journal of medicine.N Engl J Med.2016 May 5;374(18):1774-9. doi: 10.1056/NEJMcps1509470.
• PMID 27144853

• Update on the pharmacological treatment of adult myositis.

• Oddis CV1.
• Journal of internal medicine.J Intern Med.2016 Apr 20. doi: 10.1111/joim.12511. [Epub ahead of print]
• The management of patients with idiopathic inflammatory myopathy (IIM) remains a challenge given the systemic features beyond active myositis. That is, recognizing the inflammatory arthropathy, varying dermatomyositis rashes, and overt and occult features of interstitial lung disease in addition to
• PMID 27098592

Japanese Journal

• Onset of Reversible Flaccid Quadriplegia during Treatment of Thyrotoxic Crisis

• , , , , , ,
• Internal Medicine 54(4), 421-425, 2015
• … Thyrotoxicosis in addition to critical illness polyneuromyopathy and the administration of glucocorticoid therapy may have contributed to the onset of quadriplegia in these two cases. …
• NAID 130004903051

• Effects of a vitamin D analog, alfacalcidol, on bone and skeletal muscle in glucocorticoid-treated rats

• , , , ,
• Biomedical Research 31(6), 329-336, 2010
• … Glucocorticoids cause secondary osteoporosis and myopathy. … However, effects of vitamin D on muscles under glucocorticoid treatment remain unclear. … These results suggest that in glucocorticoid-treated rats, alfacalcidol preserved not only BMD, but also muscle strength and muscle volume, and prevented muscle fatigue. …
• NAID 130004470759

• Thyrotoxicosis Complicated with Dysphagia

• ,
• Internal Medicine 48(14), 1243-1245, 2009
• … Dysphagia was restored completely with 2 months after intensive treatment with anti-thyroid agent, beta-blocker, potassium iodide and glucocorticoid for thyroid storm. … Although dysphagia is an uncommon manifestation, we should keep in mind that dysphagia may be one of symptoms of thyrotoxic myopathy. …
• NAID 130000121947

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glucocorticoid myopathy

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