glucagon-like peptide-1 agonists

同

GLP-1

WordNet

1. want to have; "Id like a beer now!"
2. a kind of person; "Well not see his like again"; "I cant tolerate people of his ilk" (同)ilk
3. a similar kind; "dogs, foxes, and the like", "we dont want the likes of you around here" (同)the like, the likes of
4. equal in amount or value; "like amounts"; "equivalent amounts"; "the same amount"; "gave one six blows and the other a like number"; "the same number" (同)same
5. resembling or similar; having the same or some of the same characteristics; often used in combination; "suits of like design"; "a limited circle of like minds"; "members of the cat family have like dispositions"; "as like as two peas in a pod"; "doglike devotion"; "a dreamlike quality" (同)similar
6. be fond of; "I like my nephews"
7. feel about or towards; consider, evaluate, or regard; "How did you like the Presidents speech last night?"
8. find enjoyable or agreeable; "I like jogging"; "She likes to read Russian novels"
9. (biochemistry) a drug that can combine with a receptor on a cell to produce a physiological reaction
10. a muscle that contracts while another relaxes; "when bending the elbow the biceps are the agonist"
11. someone involved in a contest or battle (as in an agon)
12. a feeling of pleasure and enjoyment; "Ive always had a liking for reading"; "she developed a liking for gin"
13. amide combining the amino group of one amino acid with the carboxyl group of another; usually obtained by partial hydrolysis of protein
14. a hormone secreted by the pancreas; stimulates increases in blood sugar levels in the blood (thus opposing the action of insulin)

PrepTutorEJDIC

1. …‘を'『好む』,‘が'好きである / 《しばしば否定文で,またwould,《英》shouldと共に用いて》…‘を'望む,…したい / 『好む』;望む / 《複数形で》好み,好きな事
2. (外観・性質などが)…『に似た』,のような / (やり方,程度などが)…『と同じように』 / …『らしい』,にふさわいし / 《おもに話》たとえば…のような / 《名詞の前にのみ用いて》(性質・外観などが)同じの,(数量が)等しい / 《補語にのみ用いて》似ている,そっくりで / たぶん,おそらく(probably) / (…に)似た人(物),(…と)同等の人(物),匹敵する人(物)《+『of』+『名』》 / …のように / あたかも…のように
3. (…の)『好み』,趣味《+『for』(『to』)+『名』》

UpToDate Contents

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• 1. LDLコレステロール代謝の遺伝性疾患 glucagon like peptide 1 based therapies for the treatment of type 2 diabetes mellitus
• 2. ヒドロコドンおよびフェニルトロキサミン：医薬品情報 initial management of blood glucose in type 2 diabetes mellitus
• 3. 肥満の薬物療法 drug therapy of obesity
• 4. 入院患者における糖尿病のマネージメント management of diabetes mellitus in hospitalized patients
• 5. 消化管の糖尿病性自律神経ニューロパチー diabetic autonomic neuropathy of the gastrointestinal tract

English Journal

• Intestinal nutrient sensing and blood glucose control.

• Zietek T1, Daniel H.
• Current opinion in clinical nutrition and metabolic care.Curr Opin Clin Nutr Metab Care.2015 Jul;18(4):381-388.
• PURPOSE OF REVIEW: Nutrient-specific sensor systems in enteroendocrine cells detect intestinal contents and cause gut hormone release upon activation. Among these peptide hormones, the incretins glucose-dependent insulinotropic polypeptide and glucagon-like peptide 1 are of particular interest by th
• PMID 26001654

• Effects of exogenous glucagon-like peptide-1 on blood pressure, heart rate, gastric emptying, mesenteric blood flow and glycaemic responses to oral glucose in older individuals with normal glucose tolerance or type 2 diabetes.

• Trahair LG1, Horowitz M, Stevens JE, Feinle-Bisset C, Standfield S, Piscitelli D, Rayner CK, Deane AM, Jones KL.
• Diabetologia.Diabetologia.2015 Jun 6. [Epub ahead of print]
• AIMS/HYPOTHESIS: A postprandial fall in BP occurs frequently in older individuals and in patients with type 2 diabetes. The magnitude of this decrease in BP is related to the rate of gastric emptying (GE). Intravenous administration of glucagon-like peptide-1 (GLP-1) attenuates the hypotensive respo
• PMID 26048234

• GLP-1 receptor agonist treatment increases bone formation and prevents bone loss in weight-reduced obese women.

• Iepsen EW1,2, Lundgren JR1,2, Hartmann B1,2, Pedersen O2, Hansen T2, Jørgensen NR3,4, Jensen JE5, Holst JJ1,2, Madsbad S5, Torekov SS1,2.
• The Journal of clinical endocrinology and metabolism.J Clin Endocrinol Metab.2015 Jun 4:jc20151176. [Epub ahead of print]
• CONTEXT: Recent studies indicate that glucagon-like peptide 1 (GLP-1) regulates bone turnover, but the effects of GLP-1 receptor agonists (GLP-1 RAs) on bone in obese weight-reduced individuals are unknown.OBJECTIVE: To investigate the role of GLP-1 RAs on bone formation and weight loss induced bone
• PMID 26043228

Japanese Journal

• 肥満と薬物療法

• 河合 俊英,伊藤 裕
• 循環器内科 = Cardioangiology 77(6), 585-589, 2015-06
• NAID 40020522201

• GLP-1受容体作動薬 (特集 糖尿病治療薬update : 適正な血糖管理を目指して) -- (糖尿病治療薬の薬効と適応基準)

• 真下 大和,江藤 一弘
• 日本臨床 73(3), 433-437, 2015-03
• NAID 40020367139

• Impact of Either GLP-1 Agonists or DPP-4 Inhibitors on Pathophysiology of Heart Failure

• Takahashi Ayako,Ihara Madoka,Yamazaki Satoru,Asanuma Hiroshi,Asakura Masanori,Kitakaze Masafumi
• International Heart Journal 56(4), 372-376, 2015
• … Since diabetes mellitus (DM) is the most common cause of heart failure (HF), it is critically important to clarify whether incretin hormones including glucagon-like peptide-1 (GLP-1), which play an important role in blood glucose control, mediate cardioprotection. …
• NAID 130005087570

Related Links

• Glucagon-like peptide-1 (GLP-1) receptor agonists, obesity ...

COMMENTARY Glucagon-like peptide-1 (GLP-1) receptor agonists, obesity and psoriasis: diabetes meets dermatology D. J. Drucker & C. F. Rosen Received: 13 June 2011 /Accepted: 29 July 2011 # Springer-Verlag 2011 Abstract ...

• Glucagon-like peptide 1 agonists and the development and ...

Glucagon-like peptide 1 (GLP-1) is an intestine-derived insulinotropic hormone that stimulates glucose-dependent insulin production and secretion from pancreatic β-cells. Other recognized actions of GLP-1 are to suppress glucagon ...

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関

alike、as well as、care for、correspond、correspondingly、equally、favor、identically、likewise、prefer、resemble、same、similar、similarly、such