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1. 結核の自然史、微生物学、および病因 natural history microbiology and pathogenesis of tuberculosis
2. 小児における結核 tuberculosis disease in children
3. 薬剤耐性結核の疫学および分子メカニズム epidemiology and molecular mechanisms of drug resistant tuberculosis
4. 骨格系結核 skeletal tuberculosis
5. 結核と眼 tuberculosis and the eye

Maximum flow approach to prioritize potential drug targets of Mycobacterium tuberculosis H37Rv from protein-protein interaction network.

Melak T1, Gakkhar S.
Clinical and translational medicine.Clin Transl Med.2015 Dec;4(1):61. doi: 10.1186/s40169-015-0061-6. Epub 2015 Jun 5.
BACKGROUND: In spite of the implementations of several strategies, tuberculosis (TB) is overwhelmingly a serious global public health problem causing millions of infections and deaths every year. This is mainly due to the emergence of drug-resistance varieties of TB. The current treatment strategies
PMID 26061871

Doubly end-on azido bridged mixed-valence cobalt trinuclear complex: Spectral study, VTM, inhibitory effect and antimycobacterial activity on human carcinoma and tuberculosis cells.

Datta A1, Das K2, Sen C2, Karan NK2, Huang JH3, Lin CH4, Garribba E5, Sinha C6, Askun T7, Celikboyun P7, Mane SB8.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.Spectrochim Acta A Mol Biomol Spectrosc.2015 Sep 5;148:427-34. doi: 10.1016/j.saa.2015.04.014. Epub 2015 Apr 15.
Doubly end-on azido-bridged mixed-valence trinuclear cobalt complex, [Co3(L)2(N3)6(CH3OH)2] (1) is afforded by employing a potential monoanionic tetradentate-N2O2 Schiff base precursor (2-[{[2-(dimethylamino)ethyl]imino}methyl]-6-methoxyphenol; HL). Single crystal X-ray structure reveals that in 1,
PMID 25932976

Chitosan-isoniazid conjugates: Synthesis, evaluation of tuberculostatic activity, biodegradability and toxicity.

Berezin AS1, Skorik YA2.
Carbohydrate polymers.Carbohydr Polym.2015 Aug 20;127:309-15. doi: 10.1016/j.carbpol.2015.03.060. Epub 2015 Mar 30.
Novel water-soluble chitosan-isoniazid conjugates were synthesized by two methods: (1) the carbodiimide method using isoniazid (INH) and N-(2-carboxyethyl)chitosan (CEC), and (2) the reaction between INH and N-(3-chloro-2-hydroxypropyl)chitosan (CHPC). The solubility of the conjugates under physiolo
PMID 25965488